Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Jingwu Xie"'
Autor:
Dongsheng Gu, Arvin H. Soepriatna, Wenjun Zhang, Jun Li, Jenny Zhao, Xiaoli Zhang, Xianhong Shu, Yongshi Wang, Benjamin J. Landis, Craig J. Goergen, Jingwu Xie
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Background Fibrosis is a pathological wound healing process characterized by excessive extracellular matrix deposition, which interferes with normal organ function and contributes to ~ 45% of human mortality. Fibrosis develops in response to
Externí odkaz:
https://doaj.org/article/602aab8caf8142abb8ae3cb4fee8af37
Autor:
Jingwu Xie, Chi Mai Nguyen, Anita Turk, Hongmei Nan, Thomas F. Imperiale, Michael House, Kun Huang, Jing Su
Publikováno v:
Genes and Diseases, Vol 10, Iss 4, Pp 1172-1174 (2023)
Externí odkaz:
https://doaj.org/article/1431ce9f9c324a3b9e78bf95ce370a27
Publikováno v:
Genes and Diseases, Vol 9, Iss 6, Pp 1427-1430 (2022)
Externí odkaz:
https://doaj.org/article/07bf0b4008ab4b769e3eb56b04f2e4dd
Autor:
Jun Wan, Hongji Dai, Xiaoli Zhang, Sheng Liu, Yuan Lin, Ally-Khan Somani, Jingwu Xie, Jiali Han
Publikováno v:
Genes and Diseases, Vol 8, Iss 2, Pp 181-192 (2021)
The majority of non-melanoma skin cancer (NMSC) is cutaneous basal cell carcinoma (BCC) or squamous cell carcinoma (SCC), which are also called keratinocyte carcinomas, as both of them originate from keratinocytes. The incidence of keratinocyte carci
Externí odkaz:
https://doaj.org/article/a6f4ba1b10cc463b8a3b62bcfc63585e
Autor:
Mary Yinghua Zhang, Shuyi Fang, Hongyu Gao, Xiaoli Zhang, Dongsheng Gu, Yunlong Liu, Jun Wan, Jingwu Xie
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract We report our discovery of an important player in the development of skin fibrosis, a hallmark of scleroderma. Scleroderma is a fibrotic disease, affecting 70,000 to 150,000 Americans. Fibrosis is a pathological wound healing process that pr
Externí odkaz:
https://doaj.org/article/853681f9e01e40049d5b589b336c9811
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Acute myeloid leukemia (AML) is one of the most common hematopoietic malignancies that has an unfavorable outcome and a high rate of relapse. Autophagy plays a vital role in the development of and therapeutic responses to leukemia. This study identif
Externí odkaz:
https://doaj.org/article/ea00184017b9486caf93b8f918822d85
Publikováno v:
Cells, Vol 10, Iss 8, p 2030 (2021)
The hedgehog pathway, which plays a significant role in embryonic development and stem cell regulation, is activated in gastrointestinal cancers. Chemotherapy is widely used in cancer treatment. However, chemoresistance becomes a substantial obstacle
Externí odkaz:
https://doaj.org/article/8617d484d6214947ba2fa40478ec4901
Publikováno v:
Cell & Bioscience, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Colorectal cancer is a leading cause of cancer-related mortality worldwide, with Fluorouracil (5-FU)-based chemotherapy as the major treatment for advanced disease. Many patients with advanced colorectal cancer eventually succumb to the dise
Externí odkaz:
https://doaj.org/article/e8733240349242fbb64bbd69052fb210
Autor:
Dongsheng Gu, Jingwu Xie
Publikováno v:
Cancers, Vol 7, Iss 3, Pp 1684-1698 (2015)
As a major regulatory pathway for embryonic development and tissue patterning, hedgehog signaling is not active in most adult tissues, but is reactivated in a number of human cancer types. A major milestone in hedgehog signaling in cancer is the Food
Externí odkaz:
https://doaj.org/article/8235d1a4fbb94f368600c0f37b4abb04
Autor:
Dongsheng Gu, Hai Lin, Xiaoli Zhang, Qipeng Fan, Shaoxiong Chen, Safi Shahda, Yunlong Liu, Jie Sun, Jingwu Xie
Publikováno v:
Cancers, Vol 10, Iss 11, p 403 (2018)
Pancreatic cancer, mostly pancreatic ductal adenocarcinoma (PDAC), is one of the most lethal cancer types, with an estimated 44,330 death in 2018 in the US alone. While targeted therapies and immune checkpoint inhibitors have significantly improved t
Externí odkaz:
https://doaj.org/article/830fde7d13b34a008e3b8bb08e4b2616