Zobrazeno 1 - 10
of 640
pro vyhledávání: '"Jingwen Zhou"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Liver fibrosis is a common progressive liver disease that can cause liver dysfunction and lead to serious complications. Zi Qi decoction (ZQ) is a traditional formulation that exerts pharmacological effects on the treatment of liver fibrosis
Externí odkaz:
https://doaj.org/article/dd4cf61ef741420a9a9674a801b1da82
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Cartilage rarely heals spontaneously once damaged. Osteoarthritis (OA) is the most common degenerative joint disease among the elderly; however, effective treatment for OA is currently lacking. Autologous chondrocyte implantation (ACI), an i
Externí odkaz:
https://doaj.org/article/c8472ec9e67840b396a4d14c38dfd213
Publikováno v:
Synthetic and Systems Biotechnology, Vol 10, Iss 1, Pp 185-193 (2025)
Streptomyces mobaraenesis transglutaminase (smTG) can be used for site-specific labeling of proteins with chemical groups. Here, we explored the use of modified smTG for the biosynthesis of nanobody-fluorophore conjugates (NFC). smTG catalyzes the co
Externí odkaz:
https://doaj.org/article/2bf5126c5907404387b159f9216fca43
Autor:
Shan Li, Shuangshuang Luo, Xinran Yin, Xingying Zhao, Xuyang Wang, Song Gao, Sha Xu, Jian Lu, Jingwen Zhou
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 4, Pp 784-792 (2024)
The diterpene ent-copalol is an important precursor to the synthesis of andrographolide and is found only in green chiretta (Andrographis paniculata). De novo biosynthesis of ent-copalol has not been reported, because the catalytic activity of ent-co
Externí odkaz:
https://doaj.org/article/ede31bf6323f45a4ade38833f97c4134
Autor:
Zhao An, Yangyong Sun, Xiaodong Yang, Jingwen Zhou, Yongchao Yu, Boyao Zhang, Zhiyun Xu, Yuming Zhu, Guokun Wang
Publikováno v:
Non-coding RNA Research, Vol 9, Iss 4, Pp 1040-1049 (2024)
Thoracic aortic dissection (TAD) is a life-threatening vascular disease manifested as intramural bleeding in the medial layers of the thoracic aorta. The key histopathologic feature of TAD is medial degeneration, characterized by depletion of vascula
Externí odkaz:
https://doaj.org/article/2cfa720331444ea9be82a6e6f8369804
Identification of a human type XVII collagen fragment with high capacity for maintaining skin health
Autor:
Xinglong Wang, Shuyao Yu, Ruoxi Sun, Kangjie Xu, Kun Wang, Ruiyan Wang, Junli Zhang, Wenwen Tao, Shangyang Yu, Kai Linghu, Xinyi Zhao, Jingwen Zhou
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 4, Pp 733-741 (2024)
Collagen XVII (COL17) is a transmembrane protein that mediates skin homeostasis. Due to expression of full length collagen was hard to achieve in microorganisms, arising the needs for selection of collagen fragments with desired functions for microbi
Externí odkaz:
https://doaj.org/article/d6b08f6bcf434e40978bcbc4067be9ef
Publikováno v:
BMC Microbiology, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Long-term treatment with trimethoprim-sulfamethoxazole (SXT) can lead to the formation of small-colony variants (SCVs) of Staphylococcus aureus. However, the mechanism behind SCVs formation remains poorly understood. In this study
Externí odkaz:
https://doaj.org/article/c30e1b9243ba41b5a0cf6569eeec7bd0
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 2, Pp 369-379 (2024)
Gluconobacter oxydans is an important Gram-negative industrial microorganism that produces vitamin C and other products due to its efficient membrane-bound dehydrogenase system. Its incomplete oxidation system has many crucial industrial applications
Externí odkaz:
https://doaj.org/article/1698207508494a51a792da6428aff1a5
Autor:
Yangyang Li, Cen Li, Yishan Fu, Quan Zhang, Jianing Ma, Jingwen Zhou, Jianghua Li, Guocheng Du, Song Liu
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 2, Pp 209-216 (2024)
Aspergillus niger is a highly versatile fungal strain utilized in industrial production. The expression levels of recombinant genes in A. niger can be enhanced by increasing the copy number. Nevertheless, given the prolonged gene editing cycle of A.
Externí odkaz:
https://doaj.org/article/5b76d55a731840f7afdd19161f1a3d3c
Autor:
Xuchun Liang, Jingwen Zhou, Hongyun Wang, Ziyi Zhang, Mingming Yin, Yujiao Zhu, Lin Li, Chen Chen, Meng Wei, Meiyu Hu, Cuimei Zhao, Jianhua Yao, Guoping Li, Anh‐Tuan Dinh‐Xuan, Junjie Xiao, Yihua Bei
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Pulmonary arterial hypertension (PAH) is associated with aberrant pulmonary vascular smooth muscle cell (PASMC) function and vascular remodeling. MiR‐30d plays an important role in the pathogenesis of several cardiovascular disorders. Howe
Externí odkaz:
https://doaj.org/article/204c3abf2bcd470cb651ab51966b4759