Zobrazeno 1 - 10 of 106 pro vyhledávání: '"Jingwen Ji"'
1
Akademický článek
β-Lactamase inhibition profile of new amidine-substituted diazabicyclooctanes
Autor: Zafar Iqbal, Lijuan Zhai, Yuanyu Gao, Dong Tang, Xueqin Ma, Jinbo Ji, Jian Sun, Jingwen Ji, Yuanbai Liu, Rui Jiang, Yangxiu Mu, Lili He, Haikang Yang, Zhixiang Yang
Publikováno v: Beilstein Journal of Organic Chemistry, Vol 17, Iss 1, Pp 711-718 (2021)
The diazabicyclooctane (DBO) scaffold is the backbone of non-β-lactam-based second generation β-lactamase inhibitors. As part of our efforts, we have synthesized a series of DBO derivatives A1–23 containing amidine substituents at the C2 position
Externí odkaz: https://doaj.org/article/a15cc7d620484f53aae7a5e3d9970587
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2
Akademický článek
Recent Developments to Cope the Antibacterial Resistance via β-Lactamase Inhibition
Autor: Zafar Iqbal, Jian Sun, Haikang Yang, Jingwen Ji, Lili He, Lijuan Zhai, Jinbo Ji, Pengjuan Zhou, Dong Tang, Yangxiu Mu, Lin Wang, Zhixiang Yang
Publikováno v: Molecules, Vol 27, Iss 12, p 3832 (2022)
Antibacterial resistance towards the β-lactam (BL) drugs is now ubiquitous, and there is a major global health concern associated with the emergence of new β-lactamases (BLAs) as the primary cause of resistance. In addition to the development of ne
Externí odkaz: https://doaj.org/article/029785a3f66c462296c76f736aebb728
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3
Akademický článek
Substituted-Amidine Functionalized Monocyclic β-Lactams: Synthesis and In Vitro Antibacterial Profile
Autor: Lili He, Lijuan Zhai, Jian Sun, Jingwen Ji, Jinbo Ji, Yuanbai Liu, Yangxiu Mu, Yuanyu Gao, Dong Tang, Rui Jiang, Ko Ko Myo, Zaw Min Thu, Haikang Yang, Zafar Iqbal, Zhixiang Yang
Publikováno v: Journal of Chemistry, Vol 2021 (2021)
Background. Owing to the intrinsic stability against common β-lactamases and metallo-lactamases, monobactams gathered special attention in antibiotic drug development. However, so far, aztreonam is the only monobactam approved by FDA for clinical us
Externí odkaz: https://doaj.org/article/3768f418cfc6430d8ef7d03cc4f0eea8
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6
Akademický článek
Prediction of non-suicidal self-injury (NSSI) among rural Chinese junior high school students: a machine learning approach
Autor: Zhongliang Jiang, Yonghua Cui, Hui Xu, Cody Abbey, Wenjian Xu, Weitong Guo, Dongdong Zhang, Jintong Liu, Jingwen Jin, Ying Li
Publikováno v: Annals of General Psychiatry, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Aims Non-suicidal self-injury (NSSI) is a serious issue that is increasingly prevalent among children and adolescents, especially in rural areas. Developing a suitable predictive model for NSSI is crucial for early identification and interve
Externí odkaz: https://doaj.org/article/c359ae565f9b40c7ad0dc2c9993c9535
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9
Akademický článek
The outcome of advanced and recurrent cervical cancer patients treated with first-line platinum and paclitaxel with or without indication for immune checkpoint inhibitors: the comparative study
Autor: Lan Feng, Qun Shi, Shujuan Wang, Ye Zhao, Haiyan Wu, Lei Wei, Qing Hao, Zhaojun Cui, Lin Wang, Jing Zhang, Dan Zhang, Xinxin Zhan, Jingwen Jiang
Publikováno v: BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Objective Immune checkpoint inhibitor (ICI) therapy activates the immune system to recognize and eliminate cancer cells that have escaped surveillance. This study aimed to compare the treatment outcome of advanced and recurrent cervical canc
Externí odkaz: https://doaj.org/article/9d1af354234747b58713f43450b35b5f
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10
Akademický článek
Application of Music Therapy in Improving Sleep Quality and Psychological Health of Pregnant Women with Hypertension: A Retrospective Study
Autor: Yun Rong, Jingwen Jiang, Xueling Zhang, Yuntao Bu
Publikováno v: Noise and Health, Vol 26, Iss 122, Pp 332-337 (2024)
Objective: The aim of the study was to retrospectively study the effect of music therapy on sleep quality and mental health level of pregnant women with hypertension in pregnancy (HIP). Methods: A total of 188 pregnant women with gestational hyperten
Externí odkaz: https://doaj.org/article/c11fb92ebe2b44949503139eee89347d
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