Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jingwei Yao"'
Autor:
Genhong Li, Jingwei Yao, Zhen Lu, Lian Yu, Qinwei Chen, Lihong Ding, Zhihong Fang, Yin Li, Bing Xu
Publikováno v:
Drugs in R&D, Vol 23, Iss 4, Pp 439-451 (2023)
Abstract Background The FLT3/ITD mutation exists in many acute myeloid leukemia (AML) patients and is related to the poor prognosis of patients. In this study, we attempted to evaluate the antitumor activity of simvastatin, a member of the statin cla
Externí odkaz:
https://doaj.org/article/d0b6bf8fdaee4b8b94d65283df1be2e0
Autor:
Jinshui Tan, Mengya Zhong, Yanyan Hu, Guangchao Pan, Jingwei Yao, Yuanfang Tang, Hongpeng Duan, Yuelong Jiang, Weihang Shan, Jiaqi Lin, Yating Liu, Jiewen Huang, Huijian Zheng, Yong Zhou, Guo Fu, Zhifeng Li, Bing Xu, Jie Zha
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Refractory or relapsed (R/R) AML is the most challenging form of AML to treat. Due to frequent genetic mutations, therapy alternatives are limited. Here, we identified the role of ritanserin and its target DGKα in AML. Several AML cell line
Externí odkaz:
https://doaj.org/article/ed795b3fcb3644ed9cb15069fa02179c
Autor:
Jingwei Yao, Yubo Ding, Xiong Liu, Jialu Huang, Minghui Zhang, Yu Zhang, Yufan Lv, Zhuoyi Xie, Jianhong Zuo
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The research on targeted therapy of hypopharyngeal cancer is very scarce. The discovery of new targeted driver genes will promote the progress of hypopharyngeal cancer therapy to a great extent. In our research, whole-exome sequencing in 10
Externí odkaz:
https://doaj.org/article/f17ab13b0347453baac3afea219aec95
Autor:
Jingwei Yao, Zhanbin Li, Biao Zhu, Pan Zhang, Jingshu Wang, Weiying Sun, Shasha Mei, Yaqiang Zhang, Peiqing Xiao
Publikováno v:
Water, Vol 16, Iss 1, p 26 (2023)
The correlation between runoff and sediment challenges ecological preservation and sustainable development in the Yellow River Basin. An understanding of the key factors influencing variations in runoff and sediment transport in crucial river basins
Externí odkaz:
https://doaj.org/article/320dc93fd85e4ab2b484fd23112de5cc
Autor:
Qiuling Chen, Qian Lai, Yuelong Jiang, jingwei Yao, Qinwei Chen, Li Zhang, Caiyan Wang, Yong Zhou, Manman Deng, Bing Xu
Publikováno v:
Translational Oncology, Vol 25, Iss , Pp 101516- (2022)
Objectives: Despite advances in the development of novel targeted therapies, the need for B-ALL alternative treatments has not been met. Anlotinib could blunt the proangiogenic activity of VEGFR, PDGFR, and FGFR, and has shown strong antitumor activi
Externí odkaz:
https://doaj.org/article/7fd226d4a20c4acfbd8b21ecb37cb592
Autor:
Yubo Ding, Jingwei Yao, Meiling Wen, Xiong Liu, Jialu Huang, Minghui Zhang, Yu Zhang, Yufan Lv, Zhuoyi Xie, JianHong Zuo
Publikováno v:
PeerJ, Vol 10, p e13473 (2022)
Background The genome map of hepatocellular carcinoma (HCC) is complex. In order to explore whether circulating tumor cell DNA (ctDNA) can be used as the basis for sequencing and use ctDNA to find tumor related biomarkers, we analyzed the mutant gene
Externí odkaz:
https://doaj.org/article/2584ae5e7a4b46a899a40d6e5915e1d2
Autor:
Yuanfang Tang, Mengya Zhong, Guangchao Pan, Jinshui Tan, Chendi Xie, Yuelong Jiang, Jingwei Yao, Weihang Shan, Jiaqi Lin, Jiewen Huang, Yating Liu, Zhifeng Li, Bing Xu, Jie Zha
Publikováno v:
Pharmaceuticals, Vol 16, Iss 1, p 15 (2022)
Transformed follicular lymphoma (t-FL), for which there is no efficient treatment strategy, has a rapid progression, treatment resistance, and poor prognosis, which are the main reasons for FL treatment failure. In this study, we identified a promisi
Externí odkaz:
https://doaj.org/article/40f2f2cd18014b5ab8bc4a9c0019fd00
Autor:
Yu Zhang, Minghui Zhang, Zhuoyi Xie, Yubo Ding, Jialu Huang, Jingwei Yao, Yufan Lv, Jianhong Zuo
Publikováno v:
Cancers, Vol 15, Iss 1, p 134 (2022)
Migrasomes are organelles that are similar in structure to pomegranates, up to 3 μm in diameter, and contain small vesicles with a diameter of 50–100 nm. These membranous organelles grow at the intersections or tips of retracting fibers at the bac
Externí odkaz:
https://doaj.org/article/f585947568124395917fc9987582b882
Autor:
Minghui Zhang, Yu Zhang, Yubo Ding, Jialu Huang, Jingwei Yao, Zhuoyi Xie, Yufan Lv, Jianhong Zuo
Publikováno v:
Cells, Vol 11, Iss 18, p 2811 (2022)
Previous studies have shown that tumors under a hypoxic environment can induce an important hypoxia-responsive element, hypoxia-induced factor-1α (HIF-1α), which can increase tumor migration, invasion, and metastatic ability by promoting epithelial
Externí odkaz:
https://doaj.org/article/eebc434568f44904a7934af25dd0fea3
Publikováno v:
Translational Oncology, Vol 14, Iss 6, Pp 101077- (2021)
Abnormally alternative splicing events are common hallmark of diverse types of cancers. Splicing variants with aberrant functions play an important role in cancer development. Most importantly, a growing body of evidence has supported that alternativ
Externí odkaz:
https://doaj.org/article/ef551508f23a4f7d8873fe5b8380c7dc