Zobrazeno 1 - 10
of 124
pro vyhledávání: '"Jinguo Chen"'
Autor:
Richard Apps, Angélique Biancotto, Julián Candia, Yuri Kotliarov, Shira Perl, Foo Cheung, Rohit Farmer, Matthew P. Mulè, Nicholas Rachmaninoff, Jinguo Chen, Andrew J. Martins, Rongye Shi, Huizhi Zhou, Neha Bansal, Paula Schum, Matthew J. Olnes, Pedro Milanez-Almeida, Kyu Lee Han, Brian Sellers, Mario Cortese, Thomas Hagan, Nadine Rouphael, Bali Pulendran, Lisa King, Jody Manischewitz, Surender Khurana, Hana Golding, Robbert G. van der Most, Howard B. Dickler, Ronald N. Germain, Pamela L. Schwartzberg, John S. Tsang
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114706- (2024)
Summary: To gain insight into how an adjuvant impacts vaccination responses, we use systems immunology to study human H5N1 influenza vaccination with or without the adjuvant AS03, longitudinally assessing 14 time points including multiple time points
Externí odkaz:
https://doaj.org/article/68501964c395404e9b87d185f2d87bdb
Autor:
Brian Walitt, Komudi Singh, Samuel R. LaMunion, Mark Hallett, Steve Jacobson, Kong Chen, Yoshimi Enose-Akahata, Richard Apps, Jennifer J. Barb, Patrick Bedard, Robert J. Brychta, Ashura Williams Buckley, Peter D. Burbelo, Brice Calco, Brianna Cathay, Li Chen, Snigdha Chigurupati, Jinguo Chen, Foo Cheung, Lisa M. K. Chin, Benjamin W. Coleman, Amber B. Courville, Madeleine S. Deming, Bart Drinkard, Li Rebekah Feng, Luigi Ferrucci, Scott A. Gabel, Angelique Gavin, David S. Goldstein, Shahin Hassanzadeh, Sean C. Horan, Silvina G. Horovitz, Kory R. Johnson, Anita Jones Govan, Kristine M. Knutson, Joy D. Kreskow, Mark Levin, Jonathan J. Lyons, Nicholas Madian, Nasir Malik, Andrew L. Mammen, John A. McCulloch, Patrick M. McGurrin, Joshua D. Milner, Ruin Moaddel, Geoffrey A. Mueller, Amrita Mukherjee, Sandra Muñoz-Braceras, Gina Norato, Katherine Pak, Iago Pinal-Fernandez, Traian Popa, Lauren B. Reoma, Michael N. Sack, Farinaz Safavi, Leorey N. Saligan, Brian A. Sellers, Stephen Sinclair, Bryan Smith, Joseph Snow, Stacey Solin, Barbara J. Stussman, Giorgio Trinchieri, Sara A. Turner, C. Stephenie Vetter, Felipe Vial, Carlotta Vizioli, Ashley Williams, Shanna B. Yang, Center for Human Immunology, Autoimmunity, and Inflammation (CHI) Consortium, Avindra Nath
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-29 (2024)
Abstract Post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (PI-ME/CFS) is a disabling disorder, yet the clinical phenotype is poorly defined, the pathophysiology is unknown, and no disease-modifying treatments are available. We used
Externí odkaz:
https://doaj.org/article/a14b918b7de649e6975c4ac14fdd7aa8
Autor:
Emily B. Warren, Eliza M. Gordon-Lipkin, Foo Cheung, Jinguo Chen, Amrita Mukherjee, Richard Apps, John S. Tsang, Jillian Jetmore, Melissa L. Schlein, Shannon Kruk, Yuanjiu Lei, A. Phillip West, Peter J. McGuire
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background People with mitochondrial disease (MtD) are susceptible to metabolic decompensation and neurological symptom progression in response to an infection. Increasing evidence suggests that mitochondrial dysfunction may cause chronic in
Externí odkaz:
https://doaj.org/article/44675760c2e344a68fbf8c16a8ad5f5b
Autor:
Jian Lu, Raheel Ahmad, Thomas Nguyen, Jeffrey Cifello, Humza Hemani, Jiangyuan Li, Jinguo Chen, Siyi Li, Jing Wang, Achouak Achour, Joseph Chen, Meagan Colie, Ana Lustig, Christopher Dunn, Linda Zukley, Chee W. Chia, Irina Burd, Jun Zhu, Luigi Ferrucci, Nan-ping Weng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
The characterisation of T cells during aging is important to predict functional outcomes in vaccination or infection. Here the authors use flow cytometry and scRNA sequencing to transcriptionally age CD8 T cells and then use a machine learning model
Externí odkaz:
https://doaj.org/article/06820e5848b3446782b42bbc3c749de7
Autor:
Foo Cheung, Richard Apps, Lesia Dropulic, Yuri Kotliarov, Jinguo Chen, Tristan Jordan, Marc Langweiler, Julian Candia, Angelique Biancotto, Kyu Lee Han, Nicholas Rachmaninoff, Harlan Pietz, Kening Wang, John S Tsang, Jeffrey I Cohen
Publikováno v:
eLife, Vol 12 (2023)
Background: Both sex and prior exposure to pathogens are known to influence responses to immune challenges, but their combined effects are not well established in humans, particularly in early innate responses critical for shaping subsequent outcomes
Externí odkaz:
https://doaj.org/article/b81cf02b4db747b782a8a6ae3e658c3b
Autor:
Yinglun Tian, Nanfang Xu, Ming Yan, Jinguo Chen, Kan-Lin Hung, Xiangyu Hou, Shenglin Wang, Weishi Li
Publikováno v:
Neurospine, Vol 18, Iss 4, Pp 770-777 (2021)
Objective To summarize the vertebral artery (VA) pattern of 96 “sandwich” atlantoaxial dislocation (AAD) patients and to describe the strategies of reducing the injury of VA during surgery. Methods From 2009 to 2020, we retrospectively reviewed t
Externí odkaz:
https://doaj.org/article/9abdbcd078c34cc3a6dbf59d8524a6ba
Autor:
Sarfaraz A. Hasni, Sarthak Gupta, Michael Davis, Elaine Poncio, Yenealem Temesgen-Oyelakin, Philip M. Carlucci, Xinghao Wang, Mohammad Naqi, Martin P. Playford, Rishi R. Goel, Xiaobai Li, Ann J. Biehl, Isabel Ochoa-Navas, Zerai Manna, Yinghui Shi, Donald Thomas, Jinguo Chen, Angélique Biancotto, Richard Apps, Foo Cheung, Yuri Kotliarov, Ashley L. Babyak, Huizhi Zhou, Rongye Shi, Katie Stagliano, Wanxia Li Tsai, Laura Vian, Nathalia Gazaniga, Valentina Giudice, Shajia Lu, Stephen R. Brooks, Meggan MacKay, Peter Gregersen, Nehal N. Mehta, Alan T. Remaley, Betty Diamond, John J. O’ Shea, Massimo Gadina, Mariana J. Kaplan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Increased risk of premature cardiovascular disease in systemic lupus erythematosus (SLE) is not well understood, but in animal models, the Janus kinase inhibitor tofacitinib improves related phenotypes. Here the authors report a Phase 1 double-blind
Externí odkaz:
https://doaj.org/article/8b6b0cd6bcc44990af2223bf0755ce63
Autor:
Arun Rajan, Jeffrey Schlom, Chen Zhao, James Gulley, Renee Donahue, Andrew Mammen, Jinguo Chen, Matthew Mule, Andrew Martins, Iago Pinal Fernandez, John Tsang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/a8272f8e3c974fbdaac5b857d5bbc36b
Autor:
Shutong Liu, David F. Stroncek, Yingdong Zhao, Victoria Chen, Rongye Shi, Jinguo Chen, Jiaqiang Ren, Hui Liu, Hee Joon Bae, Steven L. Highfill, Ping Jin
Publikováno v:
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Bone marrow stromal cells (BMSCs) are a heterogeneous population that participates in wound healing, immune modulation and tissue regeneration. Next generation sequencing was used to analyze transcripts from single BMSCs in order
Externí odkaz:
https://doaj.org/article/69f3b7086d1a4211b1e73dd4f5f2e7db
Autor:
Cheng Zhang, Jinguo Chen, Jindong Gao, Guanglong Tan, Shaobo Bai, Kangwei Weng, Hua Min Chen, Xiaohong Ding, Huanyu Cheng, Yanhui Yang, Jun Wang
Publikováno v:
Nano Letters. 23:3435-3443