Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jingsi, Jin"'
Autor:
Song Li, Xinxing Ouyang, Hongxiang Sun, Jingsi Jin, Yao Chen, Liang Li, Qijun Wang, Yingzhong He, Jiwen Wang, Tongxin Chen, Qing Zhong, Yinming Liang, Philippe Pierre, Qiang Zou, Youqiong Ye, Bing Su
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-19 (2024)
Abstract Peripheral CD8+ T cell number is tightly controlled but the precise molecular mechanism regulating this process is still not fully understood. In this study, we found that epilepsy patients with loss of function mutation of DEPDC5 had reduce
Externí odkaz:
https://doaj.org/article/824b50abd9694c4e8e1778931ed140ef
Autor:
Junwen Qu, Dawei Li, Jingsi Jin, Nan Sun, Jiajin Wu, Chao Yang, Lingling Wu, Shaoyong Zhuang, Haoyu Wu, Ruoyang Chen, Yaofei Ren, Chen Zhong, Liang Ying, Yan Zhang, Xiaodong Yuan, Ming Zhang
Publikováno v:
Journal of the American Society of Nephrology. 34:73-87
Autor:
Lingling Wu, Yuanqin Yang, Dongqing Cao, Chao Yang, Meng Wu, Zhen Zhang, Xinran Wang, Youqiong Ye, Jinmei Li, Hui Xiao, Liufu Deng, Lu Lu, Xiangjiao Meng, Jinming Yu, Jingsi Jin, Jinke Cheng, Xiaochuan Hong, Wenwen Li
Publikováno v:
Science Advances
Description
ZBP1-MLKL necroptotic signaling bridges tumor cell damage to antitumor immune responses after radiation.
Necroptosis, a form of regulated necrosis, participates in tumor development and dying cell immunogenicity. However, it rem
ZBP1-MLKL necroptotic signaling bridges tumor cell damage to antitumor immune responses after radiation.
Necroptosis, a form of regulated necrosis, participates in tumor development and dying cell immunogenicity. However, it rem
Autor:
Chao, Yang, Jingsi, Jin, Yuanqin, Yang, Hongxiang, Sun, Lingling, Wu, Mingyi, Shen, Xiaochuan, Hong, Wenwen, Li, Lu, Lu, Dongqing, Cao, Xinran, Wang, Jing, Sun, Youqiong, Ye, Bing, Su, Liufu, Deng
Publikováno v:
Immunity. 55(7)
The incidence and mortality rates of many non-reproductive human cancers are generally higher in males than in females. However, the immunological mechanism underlying sexual differences in cancers remains elusive. Here, we demonstrated that sex-rela
Publikováno v:
National Science Review
The mammalian target of rapamycin (mTOR) is an evolutionarily conserved Ser/Thr protein kinase with essential cellular function via processing various extracellular and intracellular inputs. Two distinct multi-protein mTOR complexes (mTORC), mTORC1 a
Autor:
Xinxing Ouyang, Omotooke Arojo, Hongzhi Liu, Guojun Qu, Fubin Li, Wenqian Zhang, Yuheng Han, Yuhong Fu, Bing Su, Huihui Zhang, Qijun Wang, Chuanxin Huang, Jingsi Jin, Lu Lu, Xiaocao Xu, Adam S. Lazorchak, Lichong Yan, Chuan Ruan, Shibo Jiang, Zhengfeng Yang, Man Li, Xiaobo Liu, Dou Liu
Publikováno v:
Cell Mol Immunol
Proper control of B cell growth and metabolism is crucial for B-cell-mediated immunity, but the underlying molecular mechanisms remain incompletely understood. In this study, Sin1, a key component of mTOR complex 2 (mTORC2), specifically regulates B
Androgen receptor-mediated CD8+ T cell stemness programs drive sex differences in antitumor immunity
Autor:
Chao Yang, Jingsi Jin, Yuanqin Yang, Hongxiang Sun, Lingling Wu, Mingyi Shen, Xiaochuan Hong, Wenwen Li, Lu Lu, Dongqing Cao, Xinran Wang, Jing Sun, Youqiong Ye, Bing Su, Liufu Deng
Publikováno v:
Immunity. 55:1268-1283.e9
Autor:
Chao Yang, Yuanqin Yang, Dongqing Cao, Xinran Wang, Fanlin Li, Xuanming Yang, Juanjuan Lu, Bing Su, Jinke Cheng, Meng Wu, Xiaochuan Hong, Jingsi Jin, Liufu Deng, Lingling Wu, Wen Di, Lu Lu, Wenwen Li
Publikováno v:
Science Translational Medicine. 12
Although cGAS-STING-mediated DNA sensing in tumor cells or phagocytes is central for launching antitumor immunity, the role of intrinsic cGAS-STING activation in T cells remains unknown. Here, we observed that peripheral blood CD8+ T cells from patie
Autor:
Wenwen, Li, Lu, Lu, Juanjuan, Lu, Xinran, Wang, Chao, Yang, Jingsi, Jin, Lingling, Wu, Xiaochuan, Hong, Fanlin, Li, Dongqing, Cao, Yuanqin, Yang, Meng, Wu, Bing, Su, Jinke, Cheng, Xuanming, Yang, Wen, Di, Liufu, Deng
Publikováno v:
Science translational medicine. 12(549)
Although cGAS-STING-mediated DNA sensing in tumor cells or phagocytes is central for launching antitumor immunity, the role of intrinsic cGAS-STING activation in T cells remains unknown. Here, we observed that peripheral blood CD8
Hepatocellular carcinoma (HCC) is a subtype of malignant liver cancer with poor prognosis and limited treatment options. It is noteworthy that mechanical forces in tumor microenvironment play a pivotal role in mediating the behaviors and functions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d1d299033db3e687ec908e8a09db57e
https://europepmc.org/articles/PMC5810774/
https://europepmc.org/articles/PMC5810774/