Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jingshu, Piao"'
Publikováno v:
Pakistan journal of pharmaceutical sciences. 35(5)
Pramipexole hydrochloride (PPX) is a dopamine receptor agonist for the treatment of Parkinson's disease. It does not penetrate easily into the brain due to the presence of the blood-brain barrier (BBB), which hinders the treatment of the disease. The
Publikováno v:
AAPS PharmSciTech. 23
Griseofulvin (GF) is used as an antifungal to treat superficial skin fungal infections such as tinea capitis and tinea pedis. Currently, GF is only available in traditional oral dosage forms and suffers from poor and highly variable bioavailability,
Publikováno v:
Journal of Drug Delivery Science and Technology. 78:103939
Publikováno v:
Pakistan Journal of Pharmaceutical Sciences; Jan2023, Vol. 36 Issue 1, p171-180, 10p
Publikováno v:
International Journal of Biological Sciences
We have previously established an experimental system for oxidative DNA damage-induced tumorigenesis in the small intestine of mice. To elucidate the roles of mismatch repair genes in the tumor suppression, we performed oxidative DNA damage-induced t
Autor:
Hiroshi Honda, Takashi Yao, Yoshimichi Nakatsu, Kazumi Yamauchi, Teruhisa Tsuzuki, Takuro Isoda, Yusaku Nakabeppu, Jingshu Piao
Publikováno v:
International Journal of Biological Sciences
MUTYH is a DNA glycosylase that excises adenine paired with 8-oxoguanine to prevent mutagenesis in mammals. Biallelic germline mutations of MUTYH have been found in patients predisposed to a recessive form of familial adenomatous polyposis (MAP: MUTY
Publikováno v:
Journal of Pharmaceutical Investigation. 42:133-137
Previously, we have reported the preparation and characterization of mucoadhesive pellets of metformin hydrochloride using four high-viscosity polymers including hydroxymethylcellulose (HPMC), HPMC/carbopol, sodium carboxylmethylcellulose (Na-CMC) an
Autor:
Jingshu Piao, Kwon-Yeon Weon, Ji-Eun Lee, Yuichi Nishiyama, Ikuo Fukui, Dong-Wook Kim, Jin-Seok Kim, James D. S. Park, Jung Suk Lee
Publikováno v:
Archives of Pharmacal Research. 32:391-397
Mucoadhesive polymer-coated pellets containing metformin hydrochloride were prepared by the powder-layering technique using a centrifugal fluidizing (CF)-granulator. Four high-viscosity polymers were applied to make the pellets: 1) hydroxymethylcellu
Autor:
Masayuki Uchiyama, Jingshu Piao, Teruhisa Tsuzuki, Yoshimichi Nakatsu, Hideyoshi Harashima, Hiroyuki Kamiya
Publikováno v:
International journal of pharmaceutics. 387(1-2)
Targeted sequence alteration would be an attractive method in gene therapy and biotechnology. To achieve in vivo targeted sequence alteration, a tailed duplex DNA consisting of annealed 35mer and 794mer single-stranded DNAs was delivered by means of