Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jingsheng Niu"'
Publikováno v:
ACS Central Science, Vol 6, Iss 2, Pp 207-212 (2020)
Externí odkaz:
https://doaj.org/article/7f43f79d2fd64f49ad3fe1499aa58e15
Autor:
Jie Yang, Geng Qin, Jingsheng Niu, Yue Wei, Xuexia Li, Chuanqi Zhao, Chunyu Wang, Jinsong Ren, Xiaogang Qu
Publikováno v:
Chemical Communications. 59:1078-1081
Here, we provide an out-of-the-box G-quadruplex (G4) targeting-based strategy for rescuing mitochondrial dysfunction in Alzheimer's disease. We predict and verify the presence of G4s within the promoter of an ageing epigenetic regulator BAZ2B. G4-spe
Publikováno v:
Journal of the American Chemical Society. 144:19611-19618
Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reaction has been widely regarded as a promising avenue in bioorthogonal chemistry. The emerging heterogeneous copper catalysts have been developed with a series of exciting applications such as
Publikováno v:
Materials Today. 56:16-28
Publikováno v:
Chemistry of Materials. 33:8052-8058
Publikováno v:
Angewandte Chemie. 133:12539-12545
Publikováno v:
Angewandte Chemie International Edition. 60:12431-12437
Although chemotherapy is one of the most widely used cancer treatments, there are serious side effects, drug resistance, and secondary metastasis. To address these problems, herein we designed a bimetallic metal-organic framework (MOF) encapsulated w
Autor:
Xiaogang Qu, Yuhuan Sun, Hongshuang Qin, Jinsong Ren, Chuanqi Zhao, Jingsheng Niu, Tingting Cui
Publikováno v:
Nucleic Acids Research
Telomeric DNA, whose length homeostasis is closely correlated with immortality of cancer cells, is regarded as a molecular clock for cellular lifespan. Regarding the capacity in forming G-quadruplex, G-rich 3′-overhang (G-overhang) has been conside
Publikováno v:
Nano letters. 21(17)
Cancer stem cells (CSCs) play crucial roles in tumor initiation. Amyloid β (Aβ), which is associated with Alzheimer's disease (AD), has been identified to induce cytotoxicity in tumor cells besides brain cells. Herein, we find that oligomeric Aβ1-
Publikováno v:
Chemistry of Materials. 30:7027-7033
Although broad-spectrum antibacterial agents have been developed for antibacterial treatment, the balance of microbial flora may break and this usually results in increasing resistance. To this end...