Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jingruo Zhang"'
Autor:
Manuel A. Riquelme, Xuewei Wang, Francisca M. Acosta, Jingruo Zhang, Jeffery Chavez, Sumin Gu, Peng Zhao, Wei Xiong, Ningyan Zhang, Guo Li, Saranya Srinivasan, Chaoyu Ma, Manjeet K. Rao, Lu-Zhe Sun, Nu Zhang, Zhiqiang An, Jean X. Jiang
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114377- (2024)
Summary: Bone tissue represents the most frequent site of cancer metastasis. We developed a hemichannel-activating antibody, Cx43-M2. Cx43-M2, directly targeting osteocytes in situ, activates osteocytic hemichannels and elevates extracellular ATP, th
Externí odkaz:
https://doaj.org/article/4756bc7168ea467aa3d390ca0185e247
Autor:
Yan Zeng, Manuel A. Riquelme, Rui Hua, Jingruo Zhang, Francisca M. Acosta, Sumin Gu, Jean X. Jiang
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-18 (2022)
Abstract Background Mechanical loading promotes bone formation and osteocytes are a major mechanosensory cell in the bone. Both Piezo1 channels and connexin 43 hemichannels (Cx43 HCs) in osteocytes are important players in mechanotransduction and ana
Externí odkaz:
https://doaj.org/article/b865831796864bb998106abda01fe4d2
Publikováno v:
eLife, Vol 11 (2022)
Oxidative stress is a major risk factor that causes osteocyte cell death and bone loss. Prior studies primarily focus on the function of cell surface expressed Cx43 channels. Here, we reported a new role of mitochondrial Cx43 (mtCx43) and hemichannel
Externí odkaz:
https://doaj.org/article/c6942e1d8566413d91764d2f83cef8fb
Autor:
Francisca M. Acosta, Katerina Stojkova, Jingruo Zhang, Eric Ivan Garcia Huitron, Jean X. Jiang, Christopher R. Rathbone, Eric M. Brey
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Engineered beige adipose tissues could be used for screening therapeutic strategies or as a direct treatment for obesity and metabolic disease. Microvascular fragments are vessel structures that can be directly isolated from adipose tissue and may co
Externí odkaz:
https://doaj.org/article/9871206027a74c12b62fbd7dfa185ffb
Autor:
Lie, Xiong, Jingruo, Zhang, Hanqiang, Shi, Gaofeng, Zhu, Xiaoyan, Ji, Mengjiao, Li, Ping, Zhu, Kaitao, Luo
Publikováno v:
Experimental and Therapeutic Medicine. 25
TNFα-induced protein 1 (TNFAIP1) serve a role in neurovascular disease. However, the potential role and molecular mechanism of TNFAIP1 in cerebral ischemia-reperfusion (I/R) remains elusive. In the present study, reverse transcription-quantitative P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62cd72a972a50a87455e16172ea96992
https://doi.org/10.3892/etm.2022.11724
https://doi.org/10.3892/etm.2022.11724
Publikováno v:
Curr Osteoporos Rep
PURPOSE OF REVIEW: The goal of this review is to provide an overview of the impact and underlying mechanism of oxidative stress on connexin channel function, and their roles in skeletal aging, estrogen deficiency, and glucocorticoid excess associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecbfb519ace5451d13695e72d9dd583f
https://europepmc.org/articles/PMC8174533/
https://europepmc.org/articles/PMC8174533/
Autor:
Acosta, Francisca M., Stojkova, Katerina, Jingruo Zhang, Garcia Huitron, Eric Ivan, Jiang, Jean X., Rathbone, Christopher R., Brey, Eric M.
Publikováno v:
Journal of Tissue Engineering; Jan-Dec2022, Vol. 13, p1-17, 17p
Publikováno v:
General and Comparative Endocrinology. 206:24-29
The pervasiveness of anthropogenic light in urban environments has increased the exposure to light of many animals. Since photoperiod is a regulator of the timing of reproduction in most temperate region birds, such light sources could potentially ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69a774308ad8abfcec7ec8e1c473817a
https://doi.org/10.1016/j.ygcen.2014.05.020
https://doi.org/10.1016/j.ygcen.2014.05.020