Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jingrui Xing"'
Autor:
Kanako Ishizuka, Hiroki Kimura, Chenyao Wang, Jingrui Xing, Itaru Kushima, Yuko Arioka, Tomoko Oya-Ito, Yota Uno, Takashi Okada, Daisuke Mori, Branko Aleksic, Norio Ozaki
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153224 (2016)
Both schizophrenia (SCZ) and autism spectrum disorders (ASD) are neuropsychiatric disorders with overlapping genetic etiology. Protocadherin 15 (PCDH15), which encodes a member of the cadherin super family that contributes to neural development and f
Externí odkaz:
https://doaj.org/article/f4409ff7c584435da5bd34cb19bcd7da
Autor:
Emiko Inoue, Yuichiro Watanabe, Jingrui Xing, Itaru Kushima, Jun Egawa, Shujiro Okuda, Satoshi Hoya, Takashi Okada, Yota Uno, Kanako Ishizuka, Atsunori Sugimoto, Hirofumi Igeta, Ayako Nunokawa, Toshiro Sugiyama, Norio Ozaki, Toshiyuki Someya
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144624 (2015)
Rare variations contribute substantially to autism spectrum disorder (ASD) liability. We recently performed whole-exome sequencing in two families with affected siblings and then carried out a follow-up study and identified ceroid-lipofuscinosis neur
Externí odkaz:
https://doaj.org/article/de67fc4599cd44babb1aa5ebd4897fea
Autor:
Jingrui Xing, Chenyao Wang, Hiroki Kimura, Yuto Takasaki, Shohko Kunimoto, Akira Yoshimi, Yukako Nakamura, Takayoshi Koide, Masahiro Banno, Itaru Kushima, Yota Uno, Takashi Okada, Branko Aleksic, Masashi Ikeda, Nakao Iwata, Norio Ozaki
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112531 (2014)
BackgroundThe PTPRA gene, which encodes the protein RPTP-α, is critical to neurodevelopment. Previous linkage studies, genome-wide association studies, controlled expression analyses and animal models support an association with both schizophrenia a
Externí odkaz:
https://doaj.org/article/db830d72e3384de0bd48a84f521ff2ae
Publikováno v:
ACM Transactions on Graphics. 41:1-12
This paper presents a novel approach to simulating surface tension flow within a position-based dynamics (PBD) framework. We enhance the conventional PBD fluid method in terms of its surface representation and constraint enforcement to furnish suppor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::695008b91b0ad947cbf6b925487b55fb
https://doi.org/10.1145/3550454.3555476
https://doi.org/10.1145/3550454.3555476
Autor:
Akiko Kodama, Kozo Kaibuchi, Takashi Okada, Tomomi Aida, Branko Aleksic, Makoto Arai, Maeri Yamamoto, Teppei Shimamura, Mutsuki Amano, Hidekazu Kato, Toshitaka Nabeshima, Masahito Sawahata, Emiko Shishido, Akira Sobue, Kazuhiro Hada, Taku Nagai, Chikara Mizukoshi, Nakao Iwata, Mariko Sekiguchi, Mio Shinno, Itaru Kushima, Norio Ozaki, Ryosuke Ikeda, Ryota Hashimoto, Akira Yoshimi, Toshiya Inada, Norimichi Ito, Hisako Kubo, Masahiro Nakatochi, Kiyofumi Yamada, Tetsuya Takano, Keisuke Kuroda, Tetsushi Sakuma, Jingrui Xing, Keita Tsujimura, Kanako Ishizuka, Yuto Takasaki, Yuko Arioka, Daisuke Mori, Hiroki Kimura, Masashi Ikeda, Takashi Yamomoto, Chenyao Wang, Yanjie Yu, Kohichi Tanaka
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 10, Iss 1, Pp 1-15 (2020)
Translational Psychiatry, Vol 10, Iss 1, Pp 1-15 (2020)
Schizophrenia (SCZ) is known to be a heritable disorder; however, its multifactorial nature has significantly hampered attempts to establish its pathogenesis. Therefore, in this study, we performed genome-wide copy-number variation (CNV) analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8342a89f4935d91bbf8657d2df1fd11c
https://doi.org/10.1038/s41398-020-00917-z
https://doi.org/10.1038/s41398-020-00917-z
Autor:
Masaki Kodaira, Kanako Ishizuka, Manabu Takaki, Yingni Lin, Jun Egawa, Jingrui Xing, Masahide Usami, Miho Toyama, Shinji Sakamoto, Akira Yoshimi, Kinji Ohno, Tomoko Oya-Ito, Yota Uno, Masashi Ikeda, Mako Morikawa, Nakao Iwata, Takashi Okada, Itaru Kushima, Toshiyuki Someya, Yuto Takasaki, Daisuke Mori, Hiroki Kimura, Yuko Arioka, Yuko Okahisa, Branko Aleksic, Yukako Nakamura, Tomoko Shiino, Yanjie Yu, Norio Ozaki, Chenyao Wang
Publikováno v:
Translational Psychiatry, Vol 8, Iss 1, Pp 1-9 (2018)
Translational Psychiatry
Translational Psychiatry
In schizophrenia (SCZ) and autism spectrum disorder (ASD), the dysregulation of glutamate transmission through N-methyl-d-aspartate receptors (NMDARs) has been implicated as a potential etiological mechanism. Previous studies have accumulated evidenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea310ec6424c3098e754d1a6b2c9a1a
http://link.springer.com/article/10.1038/s41398-017-0061-y
http://link.springer.com/article/10.1038/s41398-017-0061-y
Autor:
Makoto Arai, Yuka Yasuda, Akiko Kobori, H Noma, Kanako Ishizuka, Maeri Yamamoto, Norio Ozaki, Yuko Arioka, Hidenaga Yamamori, Branko Aleksic, Michio Suzuki, Shusuke Numata, Chia-Hsiang Chen, Tomoko Toyota, Chaochen Wang, Yuichiro Watanabe, Toshimichi Yamamoto, T Maeda, Teppei Shimamura, Shuji Iritani, Tomoko Shiino, Ayako Nunokawa, Maki Morikawa, Itaru Kushima, Masanari Itokawa, Ryota Hashimoto, Akira Yoshimi, Tomoko Oya-Ito, M C Cheng, Mitsuhiro Miyashita, Toshiyuki Someya, Tsutomu Takahashi, Tetsuro Ohmori, Tetsuya Iidaka, Yota Uno, Mami Yoshida, Shohko Kunimoto, Masahiro Nakatochi, Jingrui Xing, Yuto Takasaki, Yukako Nakamura, Daisuke Mori, Takashi Okada, Hiroki Kimura, Nakao Iwata, Takeo Yoshikawa, Masashi Ikeda, Y A Chuang, Shuko Hamada
Publikováno v:
Molecular Psychiatry. 22:430-440
Recent schizophrenia (SCZ) studies have reported an increased burden of de novo copy number variants (CNVs) and identified specific high-risk CNVs, although with variable phenotype expressivity. However, the pathogenesis of SCZ has not been fully elu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4b371715d01e575bebd58179e5651d
https://doi.org/10.1038/mp.2016.88
https://doi.org/10.1038/mp.2016.88
Autor:
Mami Yoshida, Kanako Ishizuka, Jingrui Xing, Shohko Kunimoto, Naoko Tsurumaru, Branko Aleksic, Jun Egawa, Toshiyuki Someya, Yuko Arioka, Hitoshi Kuwabara, Masashi Ikeda, Chenyao Wang, Yota Uno, Itaru Kushima, Miki Aizawa, Nakao Iwata, Hiroshi Ujike, Yukako Nakamura, Mariko Sekiguchi, Norio Ozaki, Hiroki Kimura, Yuto Takasaki, Akira Yoshimi, Daisuke Mori, Takeo Yoshikawa, Tomoko Oya-Ito, Yoshimi Iwayama, Takashi Okada, Takayoshi Koide, Hiromi Noma
Publikováno v:
Scientific Reports
N-methyl-d-aspartate receptors (NMDARs) play a critical role in excitatory synaptic transmission and plasticity in the central nervous systems. Recent genetics studies in schizophrenia (SCZ) show that SCZ is susceptible to NMDARs and the NMDAR signal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4fd1bb33f049898d5bcb65dc237e53
Autor:
Takashi Okada, Hiroki Kimura, Tomoko Shiino, Yuto Takasaki, Branko Aleksic, Daisuke Mori, Norio Ozaki, Yuko Arioka, Tetsuya Iidaka, Jingrui Xing, Tomoko Oya-Ito, Chenyao Wang, Yota Uno, Yukako Nakamura, Kanako Ishizuka, Itaru Kushima, Akira Yoshimi
Publikováno v:
Scientific Reports
PSD-95 associated PSD proteins play a critical role in regulating the density and activity of glutamate receptors. Numerous previous studies have shown an association between the genes that encode these proteins and schizophrenia (SZ) and autism spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2be27563c214f81ea4055078df746f4e
https://doi.org/10.1038/srep27491
https://doi.org/10.1038/srep27491
Autor:
Yota Uno, Jingrui Xing, Chenyao Wang, Norio Ozaki, Toshiya Inada, Yuto Takasaki, Hiroki Kimura, Kanako Ishizuka, Daisuke Mori, Masashi Ikeda, Branko Aleksic, Nakao Iwata, Itaru Kushima, Takashi Okada
Publikováno v:
Schizophrenia research. 178(1-3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a07bc94c0b6fb1d744a80c0314be3e2
https://pubmed.ncbi.nlm.nih.gov/27595554
https://pubmed.ncbi.nlm.nih.gov/27595554