Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Jingrong Cui"'
Autor:
Wei Huang, Xia Yuan, Ting Sun, Shujie Fan, Jun Wang, Quan Zhou, Wei Guo, Fuxiang Ran, Zemei Ge, Huayu Yang, Runtao Li, Jingrong Cui
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/5c78fa88e4e04a34965e99e1cdd70df2
Autor:
Wei Huang, Xia Yuan, Ting Sun, Shujie Fan, Jun Wang, Quan Zhou, Wei Guo, Fuxiang Ran, Zemei Ge, Huayu Yang, Runtao Li, Jingrong Cui
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
Proteasome inhibition interfering with many cell signaling pathways has been extensively explored as a therapeutic strategy for cancers. Proteasome inhibitor YSY01A is a novel agent that has shown remarkable anti-tumor effects; however, its mechanism
Externí odkaz:
https://doaj.org/article/19f389f8dd85432db04a0369dd59f330
Publikováno v:
Molecules, Vol 16, Iss 9, Pp 7551-7564 (2011)
Based on the analysis of the crystal structure of MG101 (1) and 20S proteasomes, a new series of peptide aldehyde derivatives were designed and synthesized. Their ability to inhibit 20S proteasome was assayed. Among them, Cbz-Glu(OtBu)-Phe-Leucinal (
Externí odkaz:
https://doaj.org/article/53704fcf46b946dfb68b2cbf06832003
Autor:
Zining Cui, Yun Ling, Baoju Li, Yongqiang Li, Changhui Rui, Jingrong Cui, Yanxia Shi, Xinling Yang
Publikováno v:
Molecules, Vol 15, Iss 6, Pp 4267-4282 (2010)
In order to find novel chitin synthesis inhibitors (CSIs) with good activity, benzoylphenylurea, a typical kind of CSIs, was chosen as the lead compound and 15 novel derivatives containing furan moieties were designed by converting the urea linkage o
Externí odkaz:
https://doaj.org/article/0bf12bd40f384629b44f735300c89ea9
Publikováno v:
Molecules, Vol 14, Iss 7, Pp 2447-2457 (2009)
A series of novel 3-N-sugar-substituted quinazolinediones were synthesizedthrough the cyclization of the intermediate 2-aminobenzamides using triphosgene as the condensing reagent. Their anti-angiogenesis activities were investigated. The compound 3-
Externí odkaz:
https://doaj.org/article/be903e240e694f6ea59ea783d4980543
Autor:
Wei Huang, Xia Yuan, Ting Sun, Shujie Fan, Jun Wang, Quan Zhou, Wei Guo, Fuxiang Ran, Zemei Ge, Huayu Yang, Runtao Li, Jingrong Cui
Publikováno v:
Frontiers in Pharmacology; 2024, p01-10, 10p
Publikováno v:
Computers and Electrical Engineering. 103:108301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a17a2bb931cfac092e5a579554f28bd
https://doi.org/10.1016/j.compeleceng.2022.108301
https://doi.org/10.1016/j.compeleceng.2022.108301
Publikováno v:
Translational Cancer Research. 6:1321-1330
Background: Liver is the largest organ in the body. It constitutes 2.5% of the body weight and receives approximately 25% of the cardiac output via both the dual blood flow and the portal vein as well as the hepatic artery, the latter of which contri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e7240c0a7020caf147bd63518fff047
https://doi.org/10.21037/tcr.2017.12.16
https://doi.org/10.21037/tcr.2017.12.16
Autor:
Tian-Yan Zhou, Ridong Li, Han Liqiang, Xia Yuan, Zemei Ge, Zhenming Liu, Xingyu Wu, Jingrong Cui, Xin Wang, Runtao Li, Bo Xu, Cheng Qing, An Haoyun, Tieming Cheng
Publikováno v:
European Journal of Medicinal Chemistry. 125:925-939
A novel class of urea-containing peptide boronic acids as proteasome inhibitors was designed by introducing a urea scaffold to replace an amido bond. Compounds were synthesized and their antitumor activities were evaluated. After two rounds of optimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf813c24a7798764dfb3a6925c55c65
https://doi.org/10.1016/j.ejmech.2016.10.023
https://doi.org/10.1016/j.ejmech.2016.10.023
Autor:
Xin Wang, Jingrong Cui, Wenjie Zhang, Han Liqiang, Zemei Ge, Runtao Li, Bai Heyuan, Bo Xu, Han Zhang
Publikováno v:
Bioorganicmedicinal chemistry letters. 28(14)
Curcumin is a well-known pharmacophore and some of its derivatives are shown to target 20S proteasome recently. In this report, we designed and synthesized two series of curcumin derivatives modified with different α-amino boronic acids as potent pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35dd71e53e31c3416f6b029882c81d3c
https://pubmed.ncbi.nlm.nih.gov/29886021
https://pubmed.ncbi.nlm.nih.gov/29886021