Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Jingqiang Wei"'
Autor:
Whitney Silkworth, Michel Weïwer, Stuart L. Schreiber, Andrew M. Stern, James Spoonamore, Christina Scherer, Sivaraman Dandapani, Kristina Masson, Jingqiang Wei, Nathan T. Ross, Michelle Palmer, Boris Guichard, Benito Munoz
Publikováno v:
ACS Medicinal Chemistry Letters
The KRAS oncogene is found in up to 30% of all human tumors. In 2009, RNAi experiments revealed that lowering mRNA levels of a transcript encoding the serine/threonine kinase STK33 was selectively toxic to KRAS-dependent cancer cell lines, suggesting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fbe815e9ab716a4430c94997af6cc4
https://doi.org/10.1021/ml300246r
https://doi.org/10.1021/ml300246r
Autor:
Carol A. Mulrooney, Morgan Welzel-O’Shea, Bérénice C. Lemercier, Edward B. Holson, Landon Durak, Sarathy Kesavan, Jeremy R. Duvall, Jingqiang Wei, Florence F. Wagner, Adrien Joliton, Laura M. Panko, Maurice D. Lee, Lisa A. Marcaurelle, Lakshmi B. Akella, Haibo Liu, Emeline L. Davoine, Jason T. Lowe, Méryl Thomas, Etienne J. Donckele, Michael Foley, Byung-Chul Suh, Giovanni Muncipinto, Ann Rowley, Jean-Charles Marie, Baudouin Gerard
Publikováno v:
The Journal of Organic Chemistry. 77:7187-7211
The synthesis and diversification of a densely functionalized azetidine ring system to gain access to a wide variety of fused, bridged, and spirocyclic ring systems is described. The in vitro physicochemical and pharmacokinetic properties of represen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8203c3d71af27e48bd78615da92d79b3
https://doi.org/10.1021/jo300974j
https://doi.org/10.1021/jo300974j
Autor:
Marilyn M. Olmstead, Dean J. Tantillo, Rebecca L. Davis, Brandon Q. Mercado, Jingqiang Wei, Jared T. Shaw, James E. Biggs-Houck
Publikováno v:
The Journal of Organic Chemistry. 77:160-172
Strategies for the formation of carbon-carbon bonds from the α-thioaryl carbonyl products of substituted lactams are described. Although direct functionalization is possible, a two step process of oxidation and magnesium-sulfoxide exchange has prove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4b8dd21831f5dc15d2c2ef9b5c877db
https://doi.org/10.1021/jo201541e
https://doi.org/10.1021/jo201541e
Autor:
Troy D. Ryba, Maurice D. Lee, Stephen J. Haggarty, Surya A. Reis, Eamon Comer, Nathan T. Ross, Jingqiang Wei, Byung-Chul Suh, Michael Foley, Lakshmi B. Akella, Haibo Liu, Jason T. Lowe, Yan-Ling Zhang, Wen-Ning Zhao, Jeremy R. Duvall, Daniel M. Fass, Damian W. Young, Carol Mulrooney, Lisa A. Marcaurelle, Bhaumik A. Pandya, Ann Rowley, Michelle Palmer, Baudouin Gerard, Sivaraman Dandapani, Sarathy Kesavan, Jean-Charles Marie
Publikováno v:
Journal of the American Chemical Society. 132:16962-16976
An aldol-based ‘build/couple/pair’ (B/C/P) strategy was applied to generate a collection of stereochemically and skeletally diverse small molecules. In the build phase, a series of asymmetric syn- and anti- aldol reactions were performed to produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c575c3dd482cf0fdfd0443c446a3da8
https://doi.org/10.1021/ja105119r
https://doi.org/10.1021/ja105119r
Publikováno v:
Science in China Series B: Chemistry. 44:276-282
The photochromic properties and reaction mechanism of title compounds have been examined with steady method on compounds 3-phenyl-3-[3-methylbenzothiophene-2-yl]-3H-naphtho[2,1-b]pyran (1) and 3-phenyl-3-[benzofuran-2-yl]-3H-naphtho[2,1-b]pyran (2) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::162e42976b133ad3eac25a7f65ddb92c
https://doi.org/10.1007/bf02879618
https://doi.org/10.1007/bf02879618
Publikováno v:
Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals. 344:289-294
ABATRACT The photochromic behavior of 2-phenyl-2-(thien-2-yl)-2H-benzo [b]furano[3,2-f]benzopyran (1) and 2,2-diphenyl-2H-benzo[b] furano[3,2-f]benzopyran (2) was examined by the nanosecond laser photolysis and normal time scale analysis. The results
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a841376ca91bfe05ba95bdab53e8c7
https://doi.org/10.1080/10587250008023851
https://doi.org/10.1080/10587250008023851
Publikováno v:
Molecular Crystals and Liquid Crystals Science and Technology. Section A. Molecular Crystals and Liquid Crystals. 344:283-288
A novel photochromic compound, 3-phenyl-3-(1,2-dimethylindol-3-yl)-3H-naphtho[2,1-b] pyran (I) was synthesized and the mechanism for photochromic process of I was investigated by nanosecond laser flash photolysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa832a0010fe95eaaf2ec31bcbea8d22
https://doi.org/10.1080/10587250008023850
https://doi.org/10.1080/10587250008023850
Autor:
Jingqiang Wei, George A. Kraus
Publikováno v:
Tetrahedron Letters. 46:7511-7513
The synthesis of 6,9 di-demethoxy kushecarpin A has been achieved by the coupling of a benzofuran anion with a quinone monoketal followed by a regioselective cyclization and a stereoselective hydrogenation reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b90259e4f85c10009350f0a9d1d7e38
https://doi.org/10.1016/j.tetlet.2005.09.010
https://doi.org/10.1016/j.tetlet.2005.09.010
Autor:
Dean J. Tantillo, James E. Biggs-Houck, Marilyn M. Olmstead, Rebecca L. Davis, Jingqiang Wei, Brandon Q. Mercado, Jared T. Shaw
Publikováno v:
ChemInform. 43
Strategies for the formation of carbon–carbon bonds from the α-thioaryl carbonyl products of substituted lactams are described. Although direct functionalization is possible, a two step process of oxidation and magnesium-sulfoxide exchange has pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cec06ed1af5ce739ea57ef4bb9206221
https://doi.org/10.1002/chin.201220102
https://doi.org/10.1002/chin.201220102