Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jingqi Bao"'
Autor:
Shannon Dow, Richard Burton, Richard Smith, Jingqi Bao, Enaksha Wickremsinhe, Everett Perkins
Publikováno v:
Pharmaceutics, Vol 5, Iss 2, Pp 261-276 (2013)
Gemcitabine is an intravenously administered nucleoside analog chemotherapeutic agent. The ability to deliver this agent as an oral drug would allow greater flexibility of administration and patient convenience; however, attempts have been fraught wi
Externí odkaz:
https://doaj.org/article/37461830edae46b790335d8cbbd71a37
Publikováno v:
Chemical Communications. 59:3582-3585
Direct galvanic replacement of surface Cu with Au3+ in PtCu3 nanodendrites is used to prepare an Au-modified PtCu3 nanodendrite catalyst, which shows superior stability and activity for the methanol oxidation reaction and oxygen reduction reaction.
Publikováno v:
Materials Letters. 335:133778
Autor:
Kathleen M. Hillgren, David W. Bedwell, Bridget L. Morse, Norikazu Matsunaga, Aleksandra Galetin, Michael A. Mohutsky, J. Brian Houston, Stephen D. Hall, Jingqi Bao, Ayşe Ufuk
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 47(3)
In the present study, the beagle dog was evaluated as a preclinical model to investigate organic anion transporting polypeptide (OATP)-mediated hepatic clearance. In vitro studies were performed with nine OATP substrates in three lots of plated male
Autor:
Yangwei J. Pu, Everett J. Perkins, William D. Diseroad, David M. Bender, Anne H. Dantzig, Jeffrey A. Peterson, Deyi Zhang, Jingqi Bao, Kevin L. Law, Radhe K. Vaid, Nicholas A. Magnus, David Michael Remick, Mccarthy James R, Gregory A. Stephenson, Susan M. Reutzel-Edens, James J. Starling
Publikováno v:
Journal of Medicinal Chemistry. 52:6958-6961
The design, synthesis, and biological characterization of an orally active prodrug (3) of gemcitabine are described. Additionally, the identification of a novel co-crystal solid form of the compound is presented. Valproate amide 3 is orally bioavaila
Publikováno v:
Food and Chemical Toxicology. 40:1757-1765
The primary objective of these studies was to determine the absorption, distribution, metabolism and excretion of isoeugenol following oral and intravenous administration to male Fischer-344 rats. Following a single oral dose of [14C]isoeugenol (156
Autor:
Richard Burton, Jingqi Bao, Everett J. Perkins, Shannon Dow, Enaksha R Wickremsinhe, Richard Smith
Publikováno v:
Pharmaceutics
Volume 5
Issue 2
Pages 261-276
Pharmaceutics, Vol 5, Iss 2, Pp 261-276 (2013)
Volume 5
Issue 2
Pages 261-276
Pharmaceutics, Vol 5, Iss 2, Pp 261-276 (2013)
Gemcitabine is an intravenously administered nucleoside analog chemotherapeutic agent. The ability to deliver this agent as an oral drug would allow greater flexibility of administration and patient convenience
however, attempts have been fraugh
however, attempts have been fraugh
Autor:
Jingqi Bao, Frank P. Bymaster, Gerald W. Becker, George G. Nomikos, Christian C. Felder, Michael D. Knierman, Andrea Baker Leese, Michael J. Berna, John-Michael Sauer, Amy C. Porter, Petra A. Carter
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 301(3)
The first endocannabinoid, anandamide, was discovered in 1992. Since then, two other endocannabinoid agonists have been identified, 2-arachidonyl glycerol and, more recently, noladin ether. Here, we report the identification and pharmacological chara
Autor:
Brian D. Potts, Jingqi Bao
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 752(1)
A sensitive assay was developed for the measurement of olanzapine in rat brain tissue using HPLC with electrochemical detection. The assay has a lower limit of quantitation of 0.5 ng/ml in tissue homogenate and utilizes a liquid-liquid extraction fol
Autor:
Kenneth W. Perry, Frank P. Bymaster, Jingqi Bao, Gary D. Tollefson, David T. Wong, Wei Zhang, Brian D. Potts
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 23(3)
To understand the mechanism of the clinical efficacy of olanzapine and fluoxetine combination therapy for treatment-resistant depression (TRD), we studied the effects of olanzapine and other antipsychotics in combination with the selective serotonin