Zobrazeno 1 - 10
of 326
pro vyhledávání: '"Jingping Hu"'
Autor:
Franklin R. Toapanta, Jingping Hu, Kari Ann Shirey, Paula J. Bernal, Myron M. Levine, Thomas C. Darton, Claire S. Waddington, Andrew J. Pollard, Marcelo B. Sztein
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
An oral Controlled Human Infection Model (CHIM) with wild-type S. Typhi was re-established allowing us to explore the development of immunity. In this model, ~55% of volunteers who received the challenge reached typhoid diagnosis criteria (TD), while
Externí odkaz:
https://doaj.org/article/7f2e05bb0a404438a4c9919701980c1f
Autor:
Jingping Hu, Jinyuan Wu, Han Cao, Ning Luan, Kangyang Lin, Haihao Zhang, Dandan Gao, Zhentao Lei, Hongjun Li, Cunbao Liu
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1025 (2024)
Diarrheal disease continues to be a major cause of global morbidity and mortality among children under 5 years of age. To address the current issues associated with oral attenuated rotavirus vaccines, the study of parenteral rotavirus vaccines has pr
Externí odkaz:
https://doaj.org/article/dbc6d662bd734fb399c7f83d439565bd
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 50, Iss , Pp 100974- (2024)
Multiple myeloma is a hematological malignancy that has evolved from antibody-secreting B lymphocytes. Like other types of cancers, myeloma cells have acquired functional capabilities which are referred to as “Hallmarks of Cancer”, and one of the
Externí odkaz:
https://doaj.org/article/227a84417ffe40e18358e61f886668ea
Autor:
Franklin R. Toapanta, Jingping Hu, Shiri Meron-Sudai, Laurence A. Mulard, Armelle Phalipon, Dani Cohen, Marcelo B. Sztein
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Shigellosis is common worldwide, and it causes significant morbidity and mortality mainly in young children in low- and middle- income countries. To date, there are not broadly available licensed Shigella vaccines. A novel type of conjugate vaccine c
Externí odkaz:
https://doaj.org/article/c126aa01bac14aeca8ea6a9a6c1b1b54
Autor:
Jingping Hu, Chulian Gong, Xue Xiao, Liubing Chen, Yihan Zhang, Xiaoyue Li, Yanting Li, Xiangyang Zang, Pinjie Huang, Shaoli Zhou, Chaojin Chen
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundDexmedetomidine (DEX) has been widely applied in the anesthesia and sedation of patients with oncological diseases. However, the potential effect of DEX on tumor metastasis remains contradictory. This study follows up on patients who receiv
Externí odkaz:
https://doaj.org/article/f347e4605ddc4b6e8bbcbefeae245d88
Publikováno v:
Vaccines, Vol 11, Iss 9, p 1475 (2023)
Cell-mediated immunity (CMI) plays a key role in the effectiveness of varicella zoster virus (VZV) vaccines, and mRNA vaccines have an innate advantage in inducing CMI. Glycoprotein E (gE) has been used widely as an antigen for VZV vaccines, and carb
Externí odkaz:
https://doaj.org/article/b7c344c26cb045ebb8462debed8c209c
Publikováno v:
Viruses, Vol 15, Iss 6, p 1351 (2023)
A large amount of real-world data suggests that the emergence of variants of concern (VOCs) has brought new challenges to the fight against SARS-CoV-2 because the immune protection elicited by the existing coronavirus disease 2019 (COVID-19) vaccines
Externí odkaz:
https://doaj.org/article/237856da67a5455e802d01f47289d310
Publikováno v:
Vaccines, Vol 11, Iss 5, p 1003 (2023)
Previous studies have shown that the herpes zoster subunit vaccine Shingrix™ performs well in clinical trials. However, the key ingredient in its adjuvant, QS21, is extracted from rare plants in South America, so vaccine production is limited. Comp
Externí odkaz:
https://doaj.org/article/4d8cf89581cc49c4b4f1147eb5d8659f
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
Despite being known for more than 50 years, yuzurimine-type alkaloids have not been accessed by total synthesis. Here, the authors report the first enantioselective total synthesis of (+)-Caldaphnidine J, a highly complex yuzurimine-type Daphniphyllu
Externí odkaz:
https://doaj.org/article/56d24c15a8254f91bc01a6357360c039
Autor:
Minglong Liang, Jian Wang, Chuanjian Wu, Manman Wu, Jingping Hu, Jianfeng Dai, Hang Ruan, Sidong Xiong, Chunsheng Dong
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101221- (2021)
In cancer, the extracellular matrix is extensively remodeled during chronic inflammation, thus affecting cell transcription, differentiation, migration and cell-cell interactions. Matrix metalloproteinases can degrade the extracellular matrix of tumo
Externí odkaz:
https://doaj.org/article/9aab3ea6309742479c10f72043366d41