Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jingni He"'
Autor:
Dinghao Wang, Deshan Perera, Jingni He, Chen Cao, Pathum Kossinna, Qing Li, William Zhang, Xingyi Guo, Alexander Platt, Jingjing Wu, Qingrun Zhang
Publikováno v:
PLoS Genetics, Vol 19, Iss 12, p e1011074 (2023)
Linkage disequilibrium (LD) is a fundamental concept in genetics; critical for studying genetic associations and molecular evolution. However, LD measurements are only reliable for common genetic variants, leaving low-frequency variants unanalyzed. I
Externí odkaz:
https://doaj.org/article/dd24e50cfe7f4cf4bfb95da89d319d47
Autor:
Jingni He, Wanqing Wen, Alicia Beeghly, Zhishan Chen, Chen Cao, Xiao-Ou Shu, Wei Zheng, Quan Long, Xingyi Guo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Transcriptome-wide association studies can uncover genes involved in disease. Here, the authors extend the framework with a transcriptome-wide association study approach which incorporates transcription factor occupancy, adding tissue-specific mechan
Externí odkaz:
https://doaj.org/article/e8d3108192784612a4d99f9e1d3194de
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Cuproptosis, a new form of programmed cell death, has been recently reported to be closely related to tumor progression. However, the significance of cuproptosis-related genes (CRGs) in papillary thyroid carcinoma (PTC) is still u
Externí odkaz:
https://doaj.org/article/3c4665f58c5d4a3aa4c2efdcf69206f8
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/3f330f4ace1446a7ad3b87fa3fda5ef3
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ATP-binding cassette (ABC) transporters are a large superfamily of membrane proteins that facilitate the translocation of heterogeneous substrates. Studies indicate that ABC transporters may play important roles in various carcinomas. However, the co
Externí odkaz:
https://doaj.org/article/8d87c5f22b0a41bdb18721d556e50c82
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Ubiquitination is a posttranslational modification of proteins that significantly affects protein stability and function. The specificity of substrate recognition is determined by ubiquitin E3 ligase during ubiquitination. Human Deltex (DTX) protein
Externí odkaz:
https://doaj.org/article/475cdea34ee24571887f9e6b7198e493
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Low birth-weight (LBW) and very low birth-weight (VLBW) newborns have increased risks of brain injuries, growth failure, motor difficulties, developmental coordination disorders or delay, and adult-onset vascular diseases. However, relatively little
Externí odkaz:
https://doaj.org/article/ee7d52004a3e474c9cc0c84c0004ce31
Publikováno v:
Cardiology Plus, Vol 1, Iss 3, Pp 28-36 (2016)
Galectin-3 is a member of the β-galactoside-binding galectins and is characterized by a carbohydrate recognition domain. Galectin-3 regulates the various biological processes such as cell growth, differentiation, immune function, cancer metastasis,
Externí odkaz:
https://doaj.org/article/1dd608f569244648a5c3f1c300690076
Autor:
Lauren Mak, Deshan Perera, Raynell Lang, Pathum Kossinna, Jingni He, M. John Gill, Quan Long, Guido van Marle
Publikováno v:
Microorganisms, Vol 8, Iss 2, p 196 (2020)
Modern computational methods using patient Human Immunodeficiency Virus type 1 (HIV-1) genetic sequences can model population-wide viral transmission dynamics. Accurate transmission inferences can play a critical role in the characterization of high-
Externí odkaz:
https://doaj.org/article/8398fe5ea9d045cea9e978564c8fb8e0
Autor:
Jingni He, Ying Zhang
Publikováno v:
Acta Biomaterialia. 134:1-12
Uncontrolled tumor growth and subsequent distant metastasis are highly dependent on an adequate nutrient supply from tumor blood vessels, which have relatively different pathophysiological characteristics from those of normal vasculature. Obviously,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482eed1fafd030bc25b9864774a68ccb
https://doi.org/10.1016/j.actbio.2021.07.015
https://doi.org/10.1016/j.actbio.2021.07.015