Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jingmei Hou"'
Publikováno v:
Current Eye Research. 47:1631-1640
Cataract is the leading cause of visual impairment and reversible blindness. Despite advances in surgical removal of cataracts, cataract continues to be a leading public-health issue due to the complications after surgery. Circular RNAs (circRNAs) ha
Publikováno v:
Experimental cell research. 398(1)
Radiotherapy is a conventional approach for anti-cancer treatment, killing tumor cells through damaging cellular DNA. While increasing studies have demonstrated that tumors generated the tolerance to radiation and tumor immune system was found to be
Autor:
Zheng Li, Liping Wen, Min Sun, Fan Zhou, Qingqing Yuan, Jingmei Hou, Chencheng Yao, Hongyong Fu, Minghui Niu, Zuping He, Zheng Chen, Chong Li, Shaorong Gao, Wei-Qiang Gao, Hong Wang
Publikováno v:
Cell Death & Differentiation. 25:749-766
Generation of functional spermatids from human spermatogonial stem cells (SSCs) in vitro is of utmost importance for uncovering mechanisms underlying human germ cell development and treating infertility. Here we report a three-dimensional-induced (3D
Publikováno v:
Reproduction. 153:211-220
Generation of male germ cells from pluripotent cells could provide male gametes for treating male infertility and offer an ideal model for unveiling molecular mechanisms of spermatogenesis. However, the influence and exact molecular mechanisms, espec
Autor:
Min Sun, Zheng Chen, Liping Wen, Zheng Li, Zuping He, Qingqing Yuan, Jingmei Hou, Chencheng Yao, Minghui Niu, Fan Zhou, Hongyong Fu, Hong Wang
Publikováno v:
Oncotarget
// Zheng Chen 1, 6, * , Minghui Niu 1, * , Min Sun 1, * , Qingqing Yuan 1, * , Chencheng Yao 1 , Jingmei Hou 1 , Hong Wang 1 , Liping Wen 1 , Hongyong Fu 1 , Fan Zhou 1 , Zheng Li 2 , Zuping He 1, 3, 4, 5 1 State Key Laboratory of Oncogenes and Relat
Autor:
Qingqing Yuan, Zuping He, Chencheng Yao, Minghui Niu, Jingmei Hou, Liping Wen, Yun Liu, Zheng Li, Min Sun, Zheng Chen, Hong Wang
Publikováno v:
Oncotarget
To generate functional human hepatocytes from stem cells and/or extra-hepatic tissues could provide an important source of cells for treating liver diseases. Spermatogonial stem cells (SSCs) have an unlimited plasticity since they can dedifferentiate
Autor:
Yang Liu, Qingqing Yuan, Yanan Hai, Jingmei Hou, Chencheng Yao, Ying Guo, Minghui Niu, Min Sun, Zheng Chen, Yun Liu, Zuping He
Publikováno v:
REPRODUCTION. 150:R25-R34
Spermatogenesis is composed of three distinctive phases, which include self-renewal of spermatogonia via mitosis, spermatocytes undergoing meiosis I/II and post-meiotic development of haploid spermatids via spermiogenesis. Spermatogenesis also involv
Autor:
Liping Wen, Ruinan Shen, Qingqing Yuan, Qisheng Lin, Ruobing Jia, Chencheng Yao, Fan Zhou, Wenjie Liu, Hongyong Fu, Minghui Niu, Zheng Li, Zuping He, Zheng Chen, Min Sun, Hong Wang, Jingmei Hou
Publikováno v:
Scientific Reports
Sertoli cells are essential for regulating normal spermatogenesis. However, the mechanisms underlying human Sertoli cell development remain largely elusive. Here we examined the function and signaling pathways of BMP6 in regulating human Sertoli cell
Autor:
Zuping He, Liping Wen, Zheng Li, Minghui Niu, Min Sun, Qingqing Yuan, Yun Liu, Zheng Chen, Chencheng Yao, Jingmei Hou, Hong Wang
Publikováno v:
Oncotarget
Sertoli cells play critical roles in regulating spermatogenesis and they can be reprogrammed to the cells of other lineages, highlighting that they have significant applications in reproductive and regenerative medicine. The fate determinations of Se
Autor:
Qingqing Yuan, Shi Yang, Minghui Niu, Zheng Li, Wenxian Zeng, Jingmei Hou, Zuping He, Min Sun, Linhong Liu, Xiaobo Wang, Yang Liu, Zijue Zhu
Publikováno v:
Scientific Reports
Spermatogonial stem cells (SSCs) have significant applications in both reproductive and regenerative medicine. However, primary human SSCs are very rare and a human SSC line has not yet been available. In this study, we have for the first time report