Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Jingkui Chen"'
Publikováno v:
AIMS Bioengineering, Vol 3, Iss 3, Pp 319-336 (2016)
HEK293 cells are gaining in interest for the production of recombinant proteins. However, further understanding and engineering of cell metabolism are still needed to improve protein titers. The importance of G6PDH has already been studied regarding
Externí odkaz:
https://doaj.org/article/aa417435e5ae43048ba3e9ea88ed147d
Autor:
Manon Bardyn, Jingkui Chen, Michaël Dussiot, David Crettaz, Lucas Schmid, Emmanuel Längst, Pascal Amireault, Jean-Daniel Tissot, Mario Jolicoeur, Michel Prudent
Publikováno v:
Metabolites, Vol 10, Iss 6, p 226 (2020)
After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurren
Externí odkaz:
https://doaj.org/article/f02268a1d1a942a49446c21d6a1f1c9d
Autor:
Benoît Laflaquière, Gabrielle Leclercq, Chandarong Choey, Jingkui Chen, Sabine Peres, Caryn Ito, Mario Jolicoeur
Publikováno v:
Metabolites, Vol 8, Iss 1, p 18 (2018)
Because of their unique ability to modulate the immune system, mesenchymal stromal cells (MSCs) are widely studied to develop cell therapies for detrimental immune and inflammatory disorders. However, controlling the final cell phenotype and determin
Externí odkaz:
https://doaj.org/article/654fef3a5303418e8ba460eab7d334a2
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136815 (2015)
CHO cell culture high productivity relies on optimized culture medium management under fed-batch or perfused chemostat strategies enabling high cell densities. In this work, a dynamic metabolic model for CHO cells was further developed, calibrated an
Externí odkaz:
https://doaj.org/article/88ac728ac92f43dc9337ce54ac5d9674
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90832 (2014)
Monoclonal antibody producing Chinese hamster ovary (CHO) cells have been shown to undergo metabolic changes when engineered to produce high titers of recombinant proteins. In this work, we have studied the distinct metabolism of CHO cell clones harb
Externí odkaz:
https://doaj.org/article/76a816ffff04404ab58b442cf34f282f
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e69146 (2013)
Parkinson's disease (PD) is a multifactorial disease known to result from a variety of factors. Although age is the principal risk factor, other etiological mechanisms have been identified, including gene mutations and exposure to toxins. Deregulatio
Externí odkaz:
https://doaj.org/article/9835fb7fa69548c4a94c0c2add482d44
Autor:
Eric Claeyssen, Sonia Dorion, Audrey Clendenning, Jiang Zhou He, Owen Wally, Jingkui Chen, Evgenia L Auslender, Marie-Claude Moisan, Mario Jolicoeur, Jean Rivoal
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53898 (2013)
The metabolism of potato (Solanum tuberosum) roots constitutively over- and underexpressing hexokinase (HK, EC 2.7.1.1) was examined. An 11-fold variation in HK activity resulted in altered root growth, with antisense roots growing better than sense
Externí odkaz:
https://doaj.org/article/fbaaac63562e4473af196284b4f743b5
Autor:
Rida Javed, Hongbin Zhao, Daixin Ye, Mehwish Javed, Jingkui Chen, Congli Sun, Muhammad Arif Khan, Lin Chen, Luqman Ali Shah, Jiujun Zhang
Publikováno v:
Electrochimica Acta. 436:141452
Autor:
Jingkui Chen, Jamilah Abusarah, Jean-Pierre Bikorimana, Francis Robert, Borhane Annabi, Natasha Salame, Riam Shammaa, Sébastien Talbot, Mario Jolicoeur, Moutih Rafei, Fatemeh Khodayarian, Mohammad Balood, Abed El-Hakim El-Kadiry, Nehme El-Hachem, Samaneh Kamyabiazar, Martin Olivier, Katiane Roversi, Louis-Eric Trudeau, Jerry Pelletier
Publikováno v:
SSRN Electronic Journal.
Dendritic cells (DCs) excel at cross-presenting antigens, but their effectiveness as cancer vaccine is limited. Here, we describe an innovative vaccine approach using mesenchymal stromal cells (MSCs) engineered to express the immunoproteasome (IPr) c
Autor:
Jamilah Abusarah, Fatemeh Khodayarian, Nehme El-Hachem, Natasha Salame, Martin Olivier, Mohammad Balood, Katiane Roversi, Sebastien Talbot, Jean-Pierre Bikorimana, Jingkui Chen, Mario Jolicoeur, Louis-Eric Trudeau, Samaneh Kamyabiazar, Borhane Annabi, Francis Robert, Jerry Pelletier, Abed-El-Hakim El-Kadiry, Riam Shammaa, Moutih Rafei
Publikováno v:
Cell Reports Medicine
Summary Dendritic cells (DCs) excel at cross-presenting antigens, but their effectiveness as cancer vaccine is limited. Here, we describe a vaccination approach using mesenchymal stromal cells (MSCs) engineered to express the immunoproteasome complex