Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jingjing Luan"'
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 466:154-159
The present study aimed to develop a novel baicalin-loaded nanostructured lipid carrier (BA-NLC) system for oral delivery to enhance the bioavailability. BA-NLC were prepared by emulsion–evaporation and low temperature-solidification technique and
Publikováno v:
J. Mater. Chem. B. 2:8361-8371
Bexarotene (BEX), a high-affinity agonist for retinoid X receptors (RXRs), shows apparent biological activities and distinct inhibitive efficacy in both cancer therapy and prevention. This study exploited a folate-decorated delivery of bexarotene-loa
Autor:
Lisi Qi, Leilei Hao, Hejian Guo, Xinquan Liu, Caiyun Li, Dianrui Zhang, Tingting Li, Jingjing Luan, Qiang Zhang
Publikováno v:
Colloids and Surfaces B: Biointerfaces. 117:258-266
Amoitone B, a natural agonist to Nur77, is a promising anticancer drug. However, its application is seriously restricted due to the water-insolubility and short biological half-life. Amoitone B nanocrystals (AmB-NC) were formulated by microfluidizati
Autor:
Caiyun Li, Lisi Qi, Qiang Zhang, Leilei Hao, Hejian Guo, Dianrui Zhang, Xinquan Liu, Jingjing Luan
Publikováno v:
Drug Delivery. 20:324-330
Amoitone B, a novel compound chemically synthesized as the analogue of cytosporone B, has been proved to own superior affinity with Nur77 than its parent compound and exhibit notable anticancer activity. However, its application is seriously restrict
Publikováno v:
Immunopharmacology and Immunotoxicology. 32:133-140
Enterhemorrhagic Escherichia coli (EPEC), an important cause of severe infantile diarrheal disease in many parts of the developing world, produced several recently described virulence determinations. Several of its virulence factors are secreted by t
Autor:
Guangxi Zhai, Jingjing Luan
Publikováno v:
Current drug targets. 17(4)
Cardiovascular and cerebrovascular diseases (CCVD) are a major and increasing health burden worldwide. Although treatments have been made a certain progress, the development of novel therapies for patients remains a major research object. There are a
Publikováno v:
Journal of colloid and interface science. 428
Amoitone B is a newly synthesized derivative of antitumor drug cytosporone B, which exhibits excellent anticancer activity in vivo. Nevertheless, the water-insolubility and short biological half-life limit its further development. In the present stud
Autor:
Leilei Hao, Caiyun Li, Hejian Guo, Qiang Zhang, Dianrui Zhang, Tingting Li, Jingyi Shen, Xinquan Liu, Guangpu Liu, Lisi Qi, Yuanyuan Guo, Jingjing Luan
Publikováno v:
Journal of pharmaceutical sciences. 103(3)
A liver-targeting drug delivery system for doxorubicin (DOX), that is, DOX-loaded self-assembled nanoparticles based on galactosylated O-carboxymethyl chitosan-graft-stearic acid conjugates (Gal-OS/DOX), has been prepared. The objective of the presen
Autor:
Tingting Li, Xinquan Liu, Leilei Hao, Guangxi Zhai, Lisi Qi, Hejian Guo, Qiang Zhang, Jingjing Luan, Yuanyuan Guo, Caiyun Li, Dianrui Zhang
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 114
Amoitone B, chemically synthesized as the derivative of Cytosporone B, is a powerful agonist for Nur77 receptor. It has outstanding anticancer activity in vivo. However, the water-insolubility and short biological half-life lead to poor bioavailabili
Publikováno v:
Journal of Materials Chemistry B; 2014, Vol. 2 Issue 47, p8361-8371, 11p, 3 Charts