Improving prediction accuracy of spread through air spaces in clinical-stage T1N0 lung adenocarcinoma using computed tomography imaging modelsCentral MessagePerspective

Autor: Shihua Dou, MD, Zhuofeng Li, BS, Zhenbin Qiu, MD, Jing Zhang, PhD, Yaxi Chen, MD, Shuyuan You, MD, Mengmin Wang, MD, Hongsheng Xie, MD, Xiaoxiang Huang, MD, Yun Yi Li, Jingjing Liu, MD, Yuxin Wen, MD, Jingshan Gong, PhD, Fanli Peng, MD, Wenzhao Zhong, PhD, Xuegong Zhang, PhD, Lin Yang, PhD

Publikováno v: JTCVS Open, Vol 21, Iss , Pp 290-303 (2024)

Objectives: To develop computed tomography (CT)-based models to increase the prediction accuracy of spread through air spaces (STAS) in clinical-stage T1N0 lung adenocarcinoma. Methods: Three cohorts of patients with stage T1N0 lung adenocarcinoma (n

Externí odkaz: https://doaj.org/article/f0debae2f789487eb217ae6841d640c5

PKM1 Regulates the Expression of Autophagy and Neuroendocrine Markers in Small Cell Lung Cancer

Autor: Chenchen TANG, Yulong JIN, Peiyan ZHAO, Lin TIAN, Hui LI, Changliang YANG, Rui ZHONG, Jingjing LIU, Lixia MA, Ying CHENG

Publikováno v: Chinese Journal of Lung Cancer, Vol 27, Iss 9, Pp 645-653 (2024)

Background and objective Small cell lung cancer (SCLC) is known as recalcitrant cancer with high malignancy and heterogeneity. Immunotherapy has changed the treatment pattern of extensive-disease SCLC (ED-SCLC), but the beneficiary population is limi

Externí odkaz: https://doaj.org/article/d9c8868c41cc4d0b912d0baaa614dbbb

Expert Consensus on the Diagnosis and Treatment of FGFR Gene-Altered Solid Tumors

Autor: Chunwei Xu, Bin Lian, Juanjuan Ou, Qian Wang, Wenxian Wang, Ke Wang, Dong Wang, Zhengbo Song, Aijun Liu, Jinpu Yu, Wenzhao Zhong, Zhijie Wang, Yongchang Zhang, Jingjing Liu, Shirong Zhang, Xiuyu Cai, Anwen Liu, Wen Li, Lili Mao, Ping Zhan, Hongbing Liu, Tangfeng Lv, Liyun Miao, Lingfeng Min, Yu Chen, Jingping Yuan, Feng Wang, Zhansheng Jiang, Gen Lin, Long Huang, Xingxiang Pu, Rongbo Lin, Weifeng Liu, Chuangzhou Rao, Dongqing Lv, Zongyang Yu, Xiaoyan Li, Chuanhao Tang, Chengzhi Zhou, Junping Zhang, Junli Xue, Hui Guo, Qian Chu, Rui Meng, Jingxun Wu, Rui Zhang, Jin Zhou, Zhengfei Zhu, Yongheng Li, Hong Qiu, Fan Xia, Yuanyuan Lu, Xiaofeng Chen, Rui Ge, Enyong Dai, Yu Han, Weiwei Pan, Fei Pang, Jintao Huang, Kai Wang, Fan Wu, Bingwei Xu, Liping Wang, Youcai Zhu, Li Lin, Yanru Xie, Xinqing Lin, Jing Cai, Ling Xu, Jisheng Li, Xiaodong Jiao, Kainan Li, Jia Wei, Huijing Feng, Lin Wang, Yingying Du, Wang Yao, Xuefei Shi, Xiaomin Niu, Dongmei Yuan, Yanwen Yao, Jianhui Huang, Yue Feng, Yinbin Zhang, Pingli Sun, Hong Wang, Mingxiang Ye, Zhaofeng Wang, Yue Hao, Zhen Wang, Bin Wan, Donglai Lv, Zhanqiang Zhai, Shengjie Yang, Jing Kang, Jiatao Zhang, Chao Zhang, Lin Shi, Yina Wang, Bihui Li, Zhang Zhang, Zhongwu Li, Zhefeng Liu, Nong Yang, Lin Wu, Huijuan Wang, Gu Jin, Guansong Wang, Jiandong Wang, Meiyu Fang, Yong Fang, Yuan Li, Xiaojia Wang, Jing Chen, Yiping Zhang, Xixu Zhu, Yi Shen, Shenglin Ma, Biyun Wang, Lu Si, Yuanzhi Lu, Ziming Li, Wenfeng Fang, Yong Song

Publikováno v: Global Medical Genetics, Vol 11, Iss 04, Pp 330-343 (2024)

The fibroblast growth factor receptor (FGFR) is a crucial receptor tyrosine kinase involved in essential biological processes, including growth, development, and tissue repair. However, FGFR gene mutations, including amplification, fusion, and mutati

Externí odkaz: https://doaj.org/article/d6d893b96da4470f8696347abc7c0079

Exploring the causal effect between lipid-modifying drugs and idiopathic pulmonary fibrosis: a drug-target Mendelian randomization study

Autor: Gexiang Cai, Jingjing Liu, Mengsi Cai, Lianyou Shao

Publikováno v: Lipids in Health and Disease, Vol 23, Iss 1, Pp 1-12 (2024)

Abstract Background Idiopathic pulmonary fibrosis (IPF) is a respiratory disorder of obscure etiology and limited treatment options, possibly linked to dysregulation in lipid metabolism. While several observational studies suggest that lipid-lowering

Externí odkaz: https://doaj.org/article/c43af1f9153c4d3c9e3a77fabb06097f

Study on full-scale pores characterization and heterogeneity of coal based on low-temperature nitrogen adsorption and low-field nuclear magnetic resonance experiments

Autor: Fangchao Lu, Chiyuan Liu, Xuebo Zhang, Bing Jia, Yifang Wang, Sheng Liu, Yiju Tang, Jingjing Liu, Pan Lin

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)

Abstract The characteristics and heterogeneity of coal pores are crucial for understanding the production mechanism of coalbed methane (CBM). In this study, coal samples with varying degrees of metamorphism (0.58% ≤ R O, max ≤ 3.44%) were collect

Externí odkaz: https://doaj.org/article/dc9130ff8fc74adf9eb7ae7002fe3196