Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jingjie Mo"'
Publikováno v:
Biologicals. 82:101675
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93b2ff6c20ef523b18e2c5c7170c2865
https://doi.org/10.1016/j.biologicals.2023.101675
https://doi.org/10.1016/j.biologicals.2023.101675
Autor:
Fiona Madden, Kevin Clark, Marta C. Abad, Jingjie Mo, Caitlin O'Mahony Hartnett, Nikky Le, Barry McCarthy, Jim O'Mahony, Luke A. Gibbons, Francis Maslanka, Christopher Rode, Rosemary Rea, Kerry Robinson, Carl Rafferty, Ronan Hayes
Publikováno v:
Biotechnology Progress. 38
The Quality by Design (QbD) approach to the production of therapeutic monoclonal antibodies (mAbs) emphasizes an understanding of the production process ensuring product quality is maintained throughout. Current methods for measuring Critical Quality
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92464d4f2121ab1b0ba1fc9936763aed
https://doi.org/10.1002/btpr.3223
https://doi.org/10.1002/btpr.3223
Publikováno v:
Biologicals. 61:44-51
Monitoring cell culture metabolites, including media components and cellular byproducts, during bio manufacturing is critical for gaining insights into cell growth, productivity and product quality. Historically, cell culture metabolite analysis was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39cd5e0518d5a8dc456daf74ddb616b
https://doi.org/10.1016/j.biologicals.2019.07.003
https://doi.org/10.1016/j.biologicals.2019.07.003
Publikováno v:
IJCNN
Traditional attributed network embedding methods are designed to map structural and attribute information of networks jointly into a continuous Euclidean space, while recently a novel branch of them named binarized attributed network embedding has em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22fb7a12f286123213b5b14afc0d6953
https://doi.org/10.1109/ijcnn48605.2020.9206717
https://doi.org/10.1109/ijcnn48605.2020.9206717
Autor:
Linda Switzar, Jingjie Mo, Michael J. Lewis, Fatie Rahimi Pirkolachahi, Izabela Sokolowska, Carol McVean, Crina Balog, Lars A T Meijer, Ping Hu
Publikováno v:
Analytical chemistry. 92(3)
Liquid chromatography–mass spectrometry (LC–MS) has been widely used throughout biotherapeutic development. However, its implementation in GMP-compliant commercial quality control (QC) laboratories remains a challenge. In this publication, we des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6698193fad928ca66c48031017629def
https://pubmed.ncbi.nlm.nih.gov/31869206
https://pubmed.ncbi.nlm.nih.gov/31869206
Publikováno v:
mAbs
Glycation has been observed in antibody therapeutics manufactured by the fed-batch fermentation process. It not only increases the heterogeneity of antibodies, but also potentially affects product safety and efficacy. In this study, non-glycated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4c5779c5f323dd89b759023753718ca
http://europepmc.org/articles/PMC5916557
http://europepmc.org/articles/PMC5916557
Publikováno v:
mAbs
Methionine oxidation is a common posttranslational modification (PTM) of monoclonal antibodies (mAbs). Oxidation can reduce the in-vivo half-life, efficacy and stability of the product. Peptide mapping is commonly used to monitor the levels of oxidat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfd57466048daec4e547da63fb637a6
http://europepmc.org/articles/PMC5384710
http://europepmc.org/articles/PMC5384710
Publikováno v:
SmartWorld/SCALCOM/UIC/ATC/CBDCom/IOP/SCI
Recently, network embedding has attracted a surge of attention due to its ability to automatically extract features from graph-structured data. Though network embedding method has been intensively studied, most of the existing approaches pay attentio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb7ab4fc4844486d07833588f15d2522
https://doi.org/10.1109/smartworld-uic-atc-scalcom-iop-sci.2019.00209
https://doi.org/10.1109/smartworld-uic-atc-scalcom-iop-sci.2019.00209
Autor:
Michael Capaldi, Promod Mehndiratta, Pedro Alfonso, Sarah Aubert, Frank Shi, Adam R. Evans, Geetha Goparaju, David C. Colter, Michael J. Lewis, Lian-Chao Li, Jingjie Mo, Ping Hu
Publikováno v:
mAbs
Forced degradation experiments of monoclonal antibodies (mAbs) aid in the identification of critical quality attributes (CQAs) by studying the impact of post-translational modifications (PTMs), such as oxidation, deamidation, glycation, and isomeriza
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f25696fcd675e421a6d0552e6e77fbe
https://pubmed.ncbi.nlm.nih.gov/31161859
https://pubmed.ncbi.nlm.nih.gov/31161859
Publikováno v:
ICC
Dynamic graph link prediction has attracted increasing attention in various fields such as social networks, paper citation networks and knowledge graphs. Many models have been developed to predict the future graph structure. In this paper, we propose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee6d5b9c152dc288357fcbf9f86c081c
https://doi.org/10.1109/icc.2019.8761688
https://doi.org/10.1109/icc.2019.8761688