Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Jingjiao Song"'
Autor:
Lei Li, Sheng Li, Yun Zhou, Lu Yang, Di Zhou, Yan Yang, Mengji Lu, Dongliang Yang, Jingjiao Song
Publikováno v:
Virology Journal, Vol 14, Iss 1, Pp 1-11 (2017)
Abstract Background Hydrodynamic injection (HI) of hepatitis B virus (HBV) mouse model is an useful tool for HBV related research in vivo. However, only 40% of C57/BL6 mice injected with 10 μg HBV genome contained plasmid (pAAV-HBV1.2), serum HBsAg
Externí odkaz:
https://doaj.org/article/8c49ebc3c92d46e0a36a040a9e4e006f
Autor:
Jingjiao Song, Sheng Li, Yun Zhou, Jia Liu, Sandra Francois, Mengji Lu, Dongliang Yang, Ulf Dittmer, Kathrin Sutter
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Interferon alpha (IFNα) is commonly used for the treatment of chronic hepatitis B (CHB) patients. There are 13 different IFNα subtypes in humans, but only the subtype IFNα2 is used for clinical treatment. The antiviral activities of all o
Externí odkaz:
https://doaj.org/article/23174242175f492487c0baadadc7baf5
Autor:
Jingjiao Song, Xi Wang, Dianhai Hou, Huachao Huang, Xijia Liu, Fei Deng, Hualin Wang, Basil M Arif, Zhihong Hu, Manli Wang
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159862 (2016)
Baculoviruses are insect-specific pathogens with a generally narrow host ranges. Successful primary infection is initiated by the proper interaction of at least 8 conserved per os infectivity factors (PIFs) with the host's midgut cells, a process tha
Externí odkaz:
https://doaj.org/article/fbdfdc27c22d4ba190c5b31cbaee1dd7
Autor:
Danzhen Pan, Yong Lin, Weimin Wu, Jingjiao Song, Ejuan Zhang, Chunchen Wu, Xinwen Chen, Kanghong Hu, Dongliang Yang, Yang Xu, Mengji Lu
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125658 (2015)
Hydrodynamic injection (HI) with a replication competent hepatitis B virus (HBV) genome may lead to transient or prolonged HBV replication in mice. However, the prolonged HBV persistence after HI depends on the specific backbone of the vector carryin
Externí odkaz:
https://doaj.org/article/d1f9d0aacf3b4ddf95aec1fc4a70da05
Autor:
Jingjiao Song, Yun Zhou, Sheng Li, Baoju Wang, Xin Zheng, Jun Wu, Kathrin Gibbert, Ulf Dittmer, Mengji Lu, Dongliang Yang
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90977 (2014)
Interferon alpha (IFN-α) is commonly used for the treatment of chronic hepatitis B (CHB) patients. Many factors including viral genetics may determine the outcome of IFN-α therapy. In this study, we tested whether the expression of IFN-α directly
Externí odkaz:
https://doaj.org/article/f93e4aa3d98a4ba6b678d8efb604ee3c
Autor:
Ying Yin, Chunchen Wu, Jingjiao Song, Junzhong Wang, Ejuan Zhang, Hongyan Liu, Dongliang Yang, Xinwen Chen, Mengji Lu, Yang Xu
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22524 (2011)
BACKGROUND: Typically, DNA immunization via the intramuscular route induces specific, Th1-dominant immune responses. However, plasmids expressing viral proteins fused to cytotoxic T lymphocyte antigen 4 (CTLA-4) primed Th2-biased responses and were a
Externí odkaz:
https://doaj.org/article/14de0bdfa7404fe8b927295f97849aa1
Autor:
Lu Yang, Di Zhou, Martin Kächele, Jun Wu, Mingfa Chen, Mengji Lu, Dongliang Yang, Ulrike Protzer, Roggendorf Michael, Jingjiao Song
Background Hepatitis B virus (HBV) is a major healthy problem worldwide. Because of the narrow host range of HBV, relative research was hampered by lacking of an appropriate animal model. The natural history of woodchuck hepatitis virus (WHV) infecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc41d442e6355f84ce84e6cb27cb792
https://doi.org/10.21203/rs.3.rs-1460185/v2
https://doi.org/10.21203/rs.3.rs-1460185/v2
Publikováno v:
Zeitschrift für Gastroenterologie. 54:1343-1404
Autor:
Jingjiao Song, Di Zhou, Lei Li, Lu Yang, Yun Zhou, Dongliang Yang, Sheng Li, Yan Yang, Mengji Lu
Publikováno v:
Virology Journal
Virology Journal, Vol 14, Iss 1, Pp 1-11 (2017)
Virology Journal, Vol 14, Iss 1, Pp 1-11 (2017)
Background Hydrodynamic injection (HI) of hepatitis B virus (HBV) mouse model is an useful tool for HBV related research in vivo. However, only 40% of C57/BL6 mice injected with 10 μg HBV genome contained plasmid (pAAV-HBV1.2), serum HBsAg more than
Autor:
Ejuan Zhang, You-chen Xia, Shunmei Huang, Yan Guo, Baoju Wang, Joerg F. Schlaak, Chan Sun, Xiaoli Zhao, Yong Lin, Mengji Lu, Xin Zheng, Jun Wu, Xuecheng Yang, Junzhong Wang, Jingjiao Song, Dongliang Yang, Mingfa Chen
Publikováno v:
Journal of Virology. 88:10421-10431
We have previously shown that poly(I:C) activates murine hepatic cells to produce interferon (IFN) and suppresses hepatitis B virus (HBV) replication in vitro . Therefore, we addressed whether poly(I:C) is able to induce the clearance of HBV in vivo