Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Jinghua Bie"'
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 9, Pp 1712-1719 (2016)
While HDL-associated unesterified or free cholesterol (FC) is thought to be rapidly secreted into the bile, the fate of HDL-associated cholesteryl esters (HDL-CEs) that represent >80% of HDL-cholesterol, is only beginning to be understood. In the pre
Externí odkaz:
https://doaj.org/article/9c14aee0a5cd4a8c940bbefc1d441e00
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 4, Pp 729-738 (2014)
The liver plays a central role in the final elimination of cholesterol from the body either as bile acids or as free cholesterol (FC), and lipoprotein-derived cholesterol is the major source of total biliary cholesterol. HDL is the major lipoprotein
Externí odkaz:
https://doaj.org/article/8c9da47ba46c43249c74d014b61edcc4
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 11, Pp 3078-3084 (2013)
Liver is the sole organ responsible for the final elimination of cholesterol from the body either as biliary cholesterol or bile acids. High density lipoprotein (HDL)-derived cholesterol is the major source of biliary sterols and represents a mechani
Externí odkaz:
https://doaj.org/article/4e4c52eee58e47ef8236e50d3283b9fa
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108577 (2014)
Association between circulating lipopolysaccharide (LPS) and metabolic diseases (such as Type 2 Diabetes and atherosclerosis) has shifted the focus from Western diet-induced changes in gut microbiota per se to release of gut bacteria-derived products
Externí odkaz:
https://doaj.org/article/a12941bb73d0481e856a8006bafa4387
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 9, Pp 1712-1719 (2016)
While HDL-associated unesterified or free cholesterol (FC) is thought to be rapidly secreted into the bile, the fate of HDL-associated cholesteryl esters (HDL-CEs) that represent >80% of HDL-cholesterol, is only beginning to be understood. In the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0720b5e86a5bb8c1d67b674b0c996700
https://doi.org/10.1194/jlr.m069682
https://doi.org/10.1194/jlr.m069682
Autor:
Olga Yu. Zolotarskaya, Hongliang He, William J. Korzun, Ryan L. Wallace, Michael G. Lancina, Shobha Ghosh, Paul J. Yannie, Jing Wang, Hu Yang, Quan Yuan, Jinghua Bie
Publikováno v:
Translational research : the journal of laboratory and clinical medicine. 193
Dysfunctional macrophages underlie the development of several diseases including atherosclerosis where accumulation of cholesteryl esters and persistent inflammation are 2 of the critical macrophage processes that regulate the progression as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c386b33569bfd01479379ef43ee5717d
https://pubmed.ncbi.nlm.nih.gov/29172034
https://pubmed.ncbi.nlm.nih.gov/29172034
Publikováno v:
Clinical Lipidology. 9:429-440
Accumulation of lipid-laden macrophage foam cells in arterial wall is the hallmark of atherosclerosis, the underlying cause of cardiovascular disease (CVD). Increased uptake of cholesteryl ester-rich modified low-density lipoprotein (LDL) is thought
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c06558e81f0ffd28d302097c4efa020b
https://doi.org/10.2217/clp.14.35
https://doi.org/10.2217/clp.14.35
Autor:
Rachel Osborne, Genta Kakiyama, Siddhartha S. Ghosh, Shobha Ghosh, Kathryn E. Marqueen, Jing Wang, William J. Korzun, Jinghua Bie
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33:1795-1802
Objective— Liver is the major organ responsible for the final elimination of cholesterol from the body either as biliary cholesterol or as bile acids. Intracellular hydrolysis of lipoprotein-derived cholesteryl esters (CEs) is essential to generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8bb65b465c5667cfe747eaf166ed09
https://doi.org/10.1161/atvbaha.113.301634
https://doi.org/10.1161/atvbaha.113.301634
Publikováno v:
American Journal of Physiology-Cell Physiology. 303:C427-C435
Cholesteryl ester (CE) hydrolysis is the rate-limiting step in the removal of free cholesterol (FC) from macrophage foam cells, and several enzymes have been identified as intracellular CE hydrolases in human macrophages. We have previously reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67bb26ad2552df4b10a4ff385a182b47
https://doi.org/10.1152/ajpcell.00103.2012
https://doi.org/10.1152/ajpcell.00103.2012
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 301:R967-R974
Accumulation of cholesteryl ester (CE)-enriched macrophage foam cells is central to the development of atherosclerotic lesions. Intracellular CE hydrolysis is the rate-limiting step in the removal of free cholesterol from macrophage foam cells. Enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74cbb70316ea2b8020371abaeb454991
https://doi.org/10.1152/ajpregu.00277.2011
https://doi.org/10.1152/ajpregu.00277.2011