Zobrazeno 1 - 10
of 329
pro vyhledávání: '"Jinghua, Yan"'
Autor:
Qian Chen, Pei Du, Yuxuan Han, Xuehui Ma, Rong Zhang, Xiaoyu Rong, Xu Zhao, Renyi Ma, Huiting Yang, Anqi Zheng, Qingrui Huang, Jinghua Yan, Hui Wang, Xin Zhao, Lianpan Dai, George F. Gao, Qihui Wang
Publikováno v:
Biosafety and Health, Vol 5, Iss 2, Pp 89-100 (2023)
With continuous mutations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the severe immune escape of Omicron sub-variants urges the development of next-generation broad-spectrum vaccines, especially as booster jabs after high-level
Externí odkaz:
https://doaj.org/article/abdac6603c324832b6c2a41ca0403f53
Autor:
Jiawei Zeng, Yao Li, Linrui Jiang, Ling Luo, Yue Wang, Hao Wang, Xiaonan Han, Jian Zhao, Guanglei Gu, Min Fang, Qingrui Huang, Jinghua Yan
Publikováno v:
Emerging Microbes and Infections, Vol 12, Iss 1 (2023)
ABSTRACTCurrent unprecedented mpox outbreaks in non-endemic regions represent a global public health concern. Although two live-attenuated vaccinia virus (VACV)-based vaccines have been urgently approved for people at high risk for mpox, a safer and
Externí odkaz:
https://doaj.org/article/78b32f32a0d84e469655ed7958a96b46
Autor:
Fengze Wang, Li Li, Yang Dou, Rui Shi, Xiaomin Duan, Hongchuan Liu, Jing Zhang, DanDan Liu, Jing Wu, Yang He, Jun Lan, Bai Lu, Hui Feng, Jinghua Yan
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 548-551 (2022)
The neutralizing antibody is a potential therapeutic for the ongoing COVID-19 pandemic. As an antiviral agent, numerous mAbs recognize the epitopes that overlap with ACE2-binding sites in the SARS-CoV-2-RBD. Some studies have shown that residual chan
Externí odkaz:
https://doaj.org/article/6c4076ee56804353bcf7166d10f6e8fa
Autor:
Yaling An, Shihua Li, Xiyue Jin, Jian-bao Han, Kun Xu, Senyu Xu, Yuxuan Han, Chuanyu Liu, Tianyi Zheng, Mei Liu, Mi Yang, Tian-Zhang Song, Baoying Huang, Li Zhao, Wen Wang, Ruhan A, Yingjie Cheng, Changwei Wu, Enqi Huang, Shilong Yang, Gary Wong, Yuhai Bi, Changwen Ke, Wenjie Tan, Jinghua Yan, Yong-Tang Zheng, Lianpan Dai, George F. Gao
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1058-1071 (2022)
Safe, efficacious, and deployable vaccines are urgently needed to control COVID-19 in the large-scale vaccination campaigns. We report here the preclinical studies of an approved protein subunit vaccine against COVID-19, ZF2001, which contains tandem
Externí odkaz:
https://doaj.org/article/ff8a374f442344f5abd669d7a990dd88
Publikováno v:
Emerging Microbes and Infections, Vol 11, Iss 1, Pp 2412-2422 (2022)
The devastating economic and public health consequences caused by the COVID-19 pandemic have prompted outstanding efforts from the scientific community and pharmaceutical companies to develop antibody-based therapeutics against SARS-CoV-2. Those effo
Externí odkaz:
https://doaj.org/article/9092f0f2ad3a4a06aced5fbf51323e67
Autor:
Siyu Tian, Kai Ji, Meng Wang, Fengze Wang, Hao Wang, Weijin Huang, Qingrui Huang, Jinghua Yan
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/4780735542b346e18a0e3981a106488c
Autor:
Pengcheng Han, Chao Su, Yanfang Zhang, Chongzhi Bai, Anqi Zheng, Chengpeng Qiao, Qing Wang, Sheng Niu, Qian Chen, Yuqin Zhang, Weiwei Li, Hanyi Liao, Jing Li, Zengyuan Zhang, Heecheol Cho, Mengsu Yang, Xiaoyu Rong, Yu Hu, Niu Huang, Jinghua Yan, Qihui Wang, Xin Zhao, George Fu Gao, Jianxun Qi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
The SARS-CoV-2 spike (S) protein mediates viral entry by binding of its receptor-binding domain (RBD) to the human angiotensin-converting enzyme 2 (ACE2) receptor and mutations of the S protein may have a great impact on virus transmissibility. Here,
Externí odkaz:
https://doaj.org/article/dc7aa3eaa6504c398a72531979ddf0df
Autor:
Yongli Qin, Lina Jia, Huijiao Liu, Wenqiang Ma, Xinmin Ren, Haifeng Li, Yuanwu Liu, Haiwen Li, Shuoqian Ma, Mei Liu, Pingping Li, Jinghua Yan, Jiyan Zhang, Yangdong Guo, Hua You, Yan Guo, Nafis A. Rahman, Sławomir Wołczyński, Adam Kretowski, Dangsheng Li, Xiru Li, Fazheng Ren, Xiangdong Li
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Macrophage inflammation promotes insulin resistance during diet-induced obesity. Here the authors show that macrophage NOC4L is decreased in humans and mice with obesity, that macrophage NOC4L deficiency aggravated high-fat diet induced inflammation
Externí odkaz:
https://doaj.org/article/a3dfdc25ebb64e078e8726fcf246e13a
Autor:
Rui Shi, Jiawei Zeng, Ling Xu, Fengze Wang, Xiaomin Duan, Yue Wang, Zheng Wu, Dandan Yu, Qingrui Huang, Yong-Gang Yao, Jinghua Yan
Publikováno v:
EBioMedicine, Vol 85, Iss , Pp 104297- (2022)
Summary: Background: Increasing severe morbidity and mortality by simultaneous or sequential infections with SARS-CoV-2 and influenza A viruses (IAV), especially in the elderly and obese patients, highlight the urgency of developing a combination vac
Externí odkaz:
https://doaj.org/article/3d92c4a0c323475f8385147bf3d1e91e
Autor:
Yan Li, Zhihai Chen, Lili Wu, Lianpan Dai, Jianxun Qi, Yan Chai, Shihua Li, Qihui Wang, Zhou Tong, Sufang Ma, Xiaomin Duan, Shuning Ren, Rui Song, Mifang Liang, Wenjun Liu, Jinghua Yan, George F. Gao
Publikováno v:
The Innovation, Vol 3, Iss 6, Pp 100323- (2022)
The yellow fever virus (YFV) is a life-threatening human pathogen. Owing to the lack of available therapeutics, non-vaccinated individuals are at risk. Here, we isolated eight human monoclonal antibodies that neutralize YFV infection. Five recognized
Externí odkaz:
https://doaj.org/article/bbb1a7a1063a4c57b1ab8029bcd3ac60