Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Jinghua, Hu"'
Autor:
Jielu Hao Robichaud, Yingyi Zhang, Chuan Chen, Kai He, Yan Huang, Xu Zhang, Xiaobo Sun, Xiaoyu Ma, Gary Hardiman, Ciaran G. Morrison, Zheng Dong, Nathan K. LeBrasseur, Kun Ling, Jinghua Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Despite the importance of cellular senescence in human health, how damaged cells undergo senescence remains elusive. We have previously shown that promyelocytic leukemia nuclear body (PML-NBs) translocation of the ciliary FBF1 is essential f
Externí odkaz:
https://doaj.org/article/775317152ced4b5da1b5be5d1a47e362
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract This study aimed to reveal the soil reinforcement by shrub root systems after repeated stress from external forces, such as high winds and runoff, for extended periods in the wind-hydraulic compound erosion zone. Using the widely distributed
Externí odkaz:
https://doaj.org/article/7bf9796478484fff8f2385dd7a1b6cfa
Autor:
Jielu Hao Robichaud, Yingyi Zhang, Chuan Chen, Kai He, Yan Huang, Xu Zhang, Xiaobo Sun, Xiaoyu Ma, Gary Hardiman, Ciaran G. Morrison, Zheng Dong, Nathan K. LeBrasseur, Kun Ling, Jinghua Hu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/e99fc277afb1436d82b8ebe72b5f338b
Autor:
Huicheng Chen, Zhimao Wu, Ziwei Yan, Chuan Chen, Yingying Zhang, Qiaoling Wang, Yuqing Gao, Kun Ling, Jinghua Hu, Qing Wei
Publikováno v:
Advanced Science, Vol 11, Iss 24, Pp n/a-n/a (2024)
Abstract Serving as the cell's sensory antennae, primary cilia are linked to numerous human genetic diseases when they malfunction. DZIP1L, identified as one of the genetic causes of human autosomal recessive polycystic kidney disease (ARPKD), is an
Externí odkaz:
https://doaj.org/article/0a1206e7f6ff438d9038c6e5eef5f281
Autor:
Peng Dong, Hongshuai Lv, Weiping Jia, Jiaojiao Liu, Si Wang, Xiaohai Li, Jinghua Hu, Ling Zhao, Yikang Shi
Publikováno v:
Drug Delivery, Vol 30, Iss 1, Pp 40-50 (2023)
AbstractMost chemotherapeutic agents are nonspecific distribution and cause systemic toxicities. Polysaccharide-based conjugates are promising strategies to overcome these drawbacks. To this end, two synergistic drugs docetaxel (DTX) and docosahexaen
Externí odkaz:
https://doaj.org/article/ff801bc35d1947fc8a86920442f56127
Autor:
Yanru Chen, Jingjia Li, Lulan Pu, Jinghua Hu, Lingyu Fang, Fangfang Zhou, Hongying Zhang, Yi Yang, Xinxin Rong, Shishan Deng, Lingmi Hou
Publikováno v:
Discover Oncology, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Purpose Breast cancer is the most common cancer worldwide. Low DNAJB4 expression levels are strongly correlated with poor prognosis in breast cancer patients. However, the molecular mechanism by which DNAJB4 regulates breast cancer progressi
Externí odkaz:
https://doaj.org/article/444ae4e1a1834fa08c53a00f1045089b
Autor:
Xiaoyu Ma, Yingyi Zhang, Yuanyuan Zhang, Xu Zhang, Yan Huang, Kai He, Chuan Chen, Jielu Hao, Debiao Zhao, Nathan K. LeBrasseur, James L. Kirkland, Eduardo N. Chini, Qing Wei, Kun Ling, Jinghua Hu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Exposure to irreparable stresses induces transient ciliogenesis, enabling communication with PML-NBs via a FBF1 pathway to trigger senescence in mammalian cells. Fbf1 ablation reduces senescence and associated health decline in mice, highlighting cil
Externí odkaz:
https://doaj.org/article/880ce8033dc74d578533b640039e7438
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Rheumatoid arthritis (RA) is a common autoimmune disease that can lead to severe joint damage and disability. And early diagnosis and treatment of RA can avert or substantially slow the progression of joint damage in up to 90% of patients, t
Externí odkaz:
https://doaj.org/article/d6ed59352a5b467f9ed088d09dfe48fa
Publikováno v:
Jin'gangshi yu moliao moju gongcheng, Vol 42, Iss 4, Pp 481-487 (2022)
According to the characteristics of elbow erosion damage position, a new differential processing technology was proposed. Using the flexibility of the manipulator, the machining gap between the inner and the outer side of the elbow was changed in the
Externí odkaz:
https://doaj.org/article/367f2da032764846b6fd0f1f744133d1
Autor:
Jinghua HU
Publikováno v:
Zhongguo Jianchuan Yanjiu, Vol 16, Iss Supp1, Pp 55-60 (2021)
ObjectiveTo address the problem of the increased height of the center of gravity caused by the installation of testing equipment and relevant supporting construction in refitting, it is necessary to apply adequate technical measures to control the st
Externí odkaz:
https://doaj.org/article/b9656e08aee046c7bd7962275d91b012