Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Jinghong Wan"'
Autor:
Morgane Mabire, Pushpa Hegde, Adel Hammoutene, Jinghong Wan, Charles Caër, Rola Al Sayegh, Mathilde Cadoux, Manon Allaire, Emmanuel Weiss, Tristan Thibault-Sogorb, Olivier Lantz, Michèle Goodhardt, Valérie Paradis, Pierre de la Grange, Hélène Gilgenkrantz, Sophie Lotersztajn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Liver cirrhosis is characterised by extensive fibrosis of the liver, and understanding the underpinning immunological processes is important in designing intervention. Here authors show that Mucosal-Associated Invariant T cells are instrumental to co
Externí odkaz:
https://doaj.org/article/49d8dca78ad94f9fac7e66da26a40cc1
Autor:
Manon Allaire, Rola Al Sayegh, Morgane Mabire, Adel Hammoutene, Matthieu Siebert, Charles Caër, Mathilde Cadoux, JingHong Wan, Aida Habib, Maude Le Gall, Pierre de la Grange, Hervé Guillou, Catherine Postic, Valérie Paradis, Sophie Lotersztajn, Hélène Gilgenkrantz
Publikováno v:
JHEP Reports, Vol 5, Iss 8, Pp 100794- (2023)
Background & Aims: Liver regeneration is a repair process in which metabolic reprogramming of parenchymal and inflammatory cells plays a major role. Monoacylglycerol lipase (MAGL) is an ubiquitous enzyme at the crossroad between lipid metabolism and
Externí odkaz:
https://doaj.org/article/346571883a5f4eb1b52cd8a45a9591b1
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2022)
AimAngiogenesis plays a vital role in airway remodeling in chronic asthma. ORMDL3 has been identified to be closely associated with the development of asthma remodeling. This study was to investigate the mechanism of ORMDL3 in angiogenesis of chronic
Externí odkaz:
https://doaj.org/article/01f418c0585c4671b0274c376a2e92b6
Autor:
Pushpa Hegde, Emmanuel Weiss, Valérie Paradis, Jinghong Wan, Morgane Mabire, Sukriti Sukriti, Pierre-Emmanuel Rautou, Miguel Albuquerque, Olivia Picq, Abhishak Chandra Gupta, Gladys Ferrere, Hélène Gilgenkrantz, Badr Kiaf, Amine Toubal, Lucie Beaudoin, Philippe Lettéron, Richard Moreau, Agnès Lehuen, Sophie Lotersztajn
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Hepatic fibrosis represents the liver response to chronic injury and can lead to cirrhosis. Here the authors show that mucosal-associated invariant T cells mediate chronic inflammation and fibrogenesis in the liver by inducing a proinflammatory pheno
Externí odkaz:
https://doaj.org/article/68dba654aed943aea66393450ba3bbd9
Autor:
Magdalena Janzi, Ronald Sjöberg, Jinghong Wan, Björn Fischler, Ulrika von Döbeln, Lourdes Isaac, Peter Nilsson, Lennart Hammarström
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5321 (2009)
BACKGROUND: Dried blood spot samples (DBSS) from newborns are widely used in neonatal screening for selected metabolic diseases and diagnostic possibilities for additional disorders are continuously being evaluated. Primary immunodeficiency disorders
Externí odkaz:
https://doaj.org/article/0e27e9c0d6fe43b1ab48d301c83ba79f
Autor:
Manon Allaire, Rola Al-Sayegh, Morgane Mabire, Matthieu Siebert, Mathilde Cadoux, JingHong Wan, Maude Le Gall, Catherine Postic, Hervé Guillou, Pierre de la Grange, Sophie Lotersztajn, Hélène Gilgenkrantz
Meeting AbstractOS084
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314b488b7e0e861125d8459dca30f56d
https://hal.inrae.fr/hal-03765301
https://hal.inrae.fr/hal-03765301
Autor:
Pierre-Marie Choinier, Linda Broer, Jinghong Wan, Marcelle Bens, Emmanuel Weiss, Morgane Mabire, Sanae Ben Mkaddem, Sophie Lotersztajn, Patrice Codogno, Richard Moreau, Renato C. Monteiro, Tristan Thibault-Sogorb, Loredana Saveanu, Pushpa Hegde, Hélène Gilgenkrantz
Publikováno v:
Autophagy
Control of systemic and hepatic inflammation, in particular originating from monocytes/macrophages, is crucial to prevent liver fibrosis and its progression to end-stage cirrhosis. LC3-associated phagocytosis (LAP) is a non-canonical form of autophag
Autor:
Morgane Mabire, Hegde Pushpa, Hammoutene Adel, JingHong Wan, Manon Allaire, Al Sayegh Rola, Tristan Thibault-Sogorb, Emmanuel Weiss, Valérie Paradis, Pierre de la Grange, Hélène Gilgenkrantz, Sophie Lotersztajn
Publikováno v:
Journal of Hepatology. 77:S475
Autor:
Françoise Lenfant, Anne Fougerat, Cheng Zhang, Laurence Gamet-Payrastre, Marion Régnier, Maeva Guillaume, Lorraine Smith, Thierry Levade, Arnaud Polizzi, Yannick Lippi, Caroline Sommer, Marine Huillet, Talal Al Saati, Hervé Guillou, Sandrine Lagarrigue, Sarra Smati, Nicolas Loiseau, Jinghong Wan, Catherine Postic, Yuna Blum, Alain Marrot, Adil Mardinoglu, Tiffany Fougeray, Muhammad Arif, Walter Wahli, Blandine Tramunt, Christophe Bureau, Patricia Dubot, Pierre Gourdy, Sandrine Ellero-Simatos, Céline Lukowicz, Alexandra Montagner, Frédéric Lasserre, Rémy Burcelin, Aurélie Batut, Claire Naylies, Jean-François Arnal, Alexia Laroyenne, Nathalie Hennuyer, Sophie Lotersztajn, Justine Bertrand-Michel, Bart Staels, Jean-Philippe Pradère
Publikováno v:
Gut
Gut, BMJ Publishing Group, 2021, pp.gutjnl-2020-323323. ⟨10.1136/gutjnl-2020-323323⟩
Gut, 2022, 71 (4), pp.807-821. ⟨10.1136/gutjnl-2020-323323⟩
Gut, BMJ Publishing Group, 2021, pp.gutjnl-2020-323323. ⟨10.1136/gutjnl-2020-323323⟩
Gut, 2022, 71 (4), pp.807-821. ⟨10.1136/gutjnl-2020-323323⟩
ObjectiveWe evaluated the influence of sex on the pathophysiology of non-alcoholic fatty liver disease (NAFLD). We investigated diet-induced phenotypic responses to define sex-specific regulation between healthy liver and NAFLD to identify influentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a987a37476c5275bb1174ec735c76a14
https://hal.inrae.fr/hal-03215969
https://hal.inrae.fr/hal-03215969
Autor:
Jason R. Thonhoff, David R. Beers, Weihua Zhao, Alireza Faridar, Aaron Thome, Shixiang Wen, Aijun Zhang, Jinghong Wang, Stanley H. Appel
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
ObjectiveTo determine whether a combination therapy with abatacept (CTLA4-Ig) and interleukin-2 (IL-2) is safe and suppresses markers of oxidative stress, inflammation, and degeneration in ALS.MethodsIn this open-label study, four participants with A
Externí odkaz:
https://doaj.org/article/23b3a503a45b412f8431ba1083024eb8