Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jinghe Xie"'
Autor:
Wei Liang Gan, Xi Ren, Vanessa Hui En Ng, Larry Ng, Yangyang Song, Vincent Tano, Jian Han, Omer An, Jinghe Xie, Bryan Y.L. Ng, Daryl Jin Tai Tay, Sze Jing Tang, Haoqing Shen, Shruti Khare, Kelvin Han Chung Chong, Dan Yock Young, Bin Wu, Ramanuj DasGupta, Leilei Chen
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114400- (2024)
Summary: ADAR1-mediated RNA editing establishes immune tolerance to endogenous double-stranded RNA (dsRNA) by preventing its sensing, primarily by MDA5. Although deleting Ifih1 (encoding MDA5) rescues embryonic lethality in ADAR1-deficient mice, they
Externí odkaz:
https://doaj.org/article/c57a92f54d0c4f0eb2c899bfc4bbaec0
Autor:
Yingjie Fu, Xueyan Zhang, Haibin Wu, Pingping Zhang, Shoupei Liu, Tingting Guo, Huanhuan Shan, Yan Liang, Honglin Chen, Jinghe Xie, Yuyou Duan
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
ObjectivesNormal commitment of the endoderm of the third pharyngeal pouch (3PP) is essential for the development and differentiation of the thymus. The aim of this study was to investigate the role of transcription factor HOXA3 in the development and
Externí odkaz:
https://doaj.org/article/a5522ec378e44ae28824304835acb8e2
Autor:
Haibin Wu, Xianglian Tang, Yiyu Wang, Ning Wang, Qicong Chen, Jinghe Xie, Shoupei Liu, Zhiyong Zhong, Yaqi Qiu, Ping Situ, Mark A. Zern, Jue Wang, Honglin Chen, Yuyou Duan
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2022)
Abstract Background Human pluripotent stem cells (hPSCs) have great potential in applications for regenerative medicine and drug development. However, 3D suspension culture systems for clinical-grade hPSC large-scale production have been a major chal
Externí odkaz:
https://doaj.org/article/61cb0be9acc141f1b7c947d3391e049c
Autor:
Jinghe Xie, Tingting Guo, Zhiyong Zhong, Ning Wang, Yan Liang, Weiping Zeng, Shoupei Liu, Qicong Chen, Xianglian Tang, Haibin Wu, Shuai Zhang, Keqiang Ma, Bailin Wang, Yimeng Ou, Weili Gu, Honglin Chen, Yaqi Qiu, Yuyou Duan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Integrin β1 (ITGB1), which acts as an extracellular matrix (ECM) receptor, has gained increasing attention as a therapeutic target for the treatment of hepatocellular carcinoma (HCC). However, the underpinning mechanism of how ITGB1 drives HCC progr
Externí odkaz:
https://doaj.org/article/1e47f54d1f874ebe879f66026268a3b7
Autor:
Jue Wang, Ping Situ, Sen Chen, Haibin Wu, Xueyan Zhang, Shoupei Liu, Yiyu Wang, Jinghe Xie, Honglin Chen, Yuyou Duan
Publikováno v:
Cells, Vol 11, Iss 24, p 4117 (2022)
Hepatocytes exhibit a multi-polarized state under the in vivo physiological environment, however, human embryonic stem cell-derived hepatocytes (hEHs) rarely exhibit polarity features in a two-dimensional (2D) condition. Thus, we hypothesized whether
Externí odkaz:
https://doaj.org/article/0840a339b36a4ebc9a1adf22e3cc6caf
Autor:
Jian Han, Yangyang Song, Jinghe Xie, Vincent Tano, Haoqing Shen, Wei Liang Gan, Ng, Larry, Bryan Yik Loong Ng, Hui En Ng, Vanessa, Xiaohui Sui, Sze Jing Tang, Leilei Chen
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/1/2024, Vol. 121 Issue 40, p1-15, 33p
Autor:
Xiaoshan Duan, Jinghe Xie, Rui Zhang, Hongzhi Kong, Hongyan Shan, Guixia Xu, Yongchao Jiang, Meimei Wang
Publikováno v:
New Phytologist. 227:1235-1248
Identification and comparison of the conserved and variable downstream genes of floral organ identity regulators are critical to understanding the mechanisms underlying the commonalities and peculiarities of floral organs. Yet, because of the lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b6d7d5b88dc0b26ca7cb1302606b46
https://doi.org/10.1111/nph.16601
https://doi.org/10.1111/nph.16601
Autor:
Yimeng Ou, Bailin Wang, Shuai Zhang, Honglin Chen, Weili Gu, Yaqi Qiu, Jinghe Xie, Keqing Ma, Yuyou Duan
Background Excessive alcohol consumption has been documented to increase the risk of liver hepatocellular carcinoma (HCC) development. Accordingly, a broad interest pointed to alcohol dehydrogenases (ADHs), which display essential roles in alcohol me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91a67c38c44ec4f6a6b1276a33b8ed04
https://doi.org/10.21203/rs.3.rs-810174/v1
https://doi.org/10.21203/rs.3.rs-810174/v1
Autor:
Yuyou Duan, Honglin Chen, Yaqi Qiu, Jue Wang, Mark A. Zern, Liangxue Lai, Qicong Chen, Ping Situ, Xiajing Li, Haibin Wu, Zhiyong Zhong, Jinghe Xie, Ning Wang, Xianglian Tang
Publikováno v:
Cell Proliferation
Objectives For clinical applications of cell‐based therapies, a large quantity of human pluripotent stem cells (hPSCs) produced in standardized and scalable culture processes is required. Currently, microcarrier‐free suspension culture shows pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc75f60038f54075d0f3bce810206345
http://europepmc.org/articles/PMC8450127
http://europepmc.org/articles/PMC8450127
Autor:
Meimei Wang, Rui Zhang, Xuelian Guo, Yuannian Jiao, Hongzhi Kong, Ben Yu, Yongchao Jiang, Jinghe Xie, Kunpeng Li, Haifeng Zhao, Guixia Xu
Publikováno v:
Horticulture Research. 7
The genus Aquilegia (Ranunculaceae) has been cultivated as ornamental and medicinal plants for centuries. With petal spurs of strikingly diverse size and shape, Aquilegia has also been recognized as an excellent system for evolutionary studies. Polli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56deb7e2795a624320d4558fcab31274
https://doi.org/10.1038/s41438-020-0328-y
https://doi.org/10.1038/s41438-020-0328-y