Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jingchen Gao"'
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108688- (2024)
Summary: RNA splicing is a post-transcriptional event that regulates many physiological and pathological events. However, whether RNA splicing regulates cerebral I/R-induced brain injury remains largely unknown. In this study, we found that the chrom
Externí odkaz:
https://doaj.org/article/120e0e38785f4b428f5303bf5b4a457a
Autor:
Juan Chen, Yang Zhuang, Ya Zhang, Huabao Liao, Rui Liu, Jing Cheng, Zhifeng Zhang, Jiangdong Sun, Jingchen Gao, Xiyuran Wang, Shujun Chen, Liang Zhang, Fengyuan Che, Qi Wan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: We and others have previously demonstrated that glycine is neuroprotective in cerebral ischemia-reperfusion injury. But glycine has low permeability to the blood–brain barrier (BBB). To deliver glycine into the ischemic brain to confer
Externí odkaz:
https://doaj.org/article/0f0d0277f9e74383ae9debbde99536e4
Autor:
Xujin Yao, Congqin Li, Xiangyu Xu, Qiang Wang, Jingchen Gao, Jinyang Ren, Qi Wan, Jing Cheng, Song-Feng Chen, Jiangdong Sun, Xiaohong Huang, Yu Cui, Yuyang Wang
Publikováno v:
Molecular Neurobiology. 58:4906-4920
SET domain protein 3 (SETD3) is an actin-specific methyltransferase, a rare post-translational modification with limited known biological functions. Till now, the function of SETD3 in cerebral ischemia-reperfusion (I/R)-induced injury remains unknown
Autor:
Xiangyi Kong, Wenjie Hu, Yu Cui, Jingchen Gao, Xujin Yao, Jinyang Ren, Tao Lin, Jiangdong Sun, Yunyi Gao, Xiaohua Li, Hui Wang, Huanting Li, Fengyuan Che, Qi Wan
Publikováno v:
Molecular neurobiology. 59(12)
Propionic acid (PPA) is a critical metabolite involved in microbial fermentation, which functions to reduce fat production, inhibit inflammation, and reduce serum cholesterol levels. The role of PPA in the context of cerebral ischemia–reperfusion (
Autor:
Baiqiang Chen, Xiangyi Kong, Zhuo Li, Wenjie Hu, Han Zhou, Jingchen Gao, Yu Cui, Shifang Li, Qi Wan, Yugong Feng
Publikováno v:
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 31(8)
Aquaporin 4 (AQP4), a water channel protein, has been well studied in arterial stroke-induced brain edema. However, the role of AQP4 in cerebral venous sinus thrombosis (CVST) has not been reported. Here, we showed that AQP4 expression was increased
Autor:
Jingchen Gao, Xiyuran Wang, Xiangyi Kong, Hui Wang, Xujin Yao, Jinyang Ren, Jiangdong Sun, Yitian Wang, Ye Wei, Tao Lin, Fengyuan Che, Qi Wan
Publikováno v:
SSRN Electronic Journal.
Autor:
Xujin Yao, Jinyang Ren, Yu Cui, Songfeng Chen, Jing Cheng, Jingchen Gao, Xiaohong Huang, Jiangdong Sun, Xiangyu Xu, Xiangyi Kong, Wenjie Hu, Tao Lin, Fengyuan Che, Qi Wan
Background and Purpose: Isoleucine is a branched-chain amino acid serving as an essential nutrient resource and metabolic. However, its role in cerebral ischemic stroke remains unknown. Experimental Approach: Middle cerebral artery occlusion (MCAO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d8510035572a465829db7aeb8f34fa1
https://doi.org/10.22541/au.163525012.23548218/v1
https://doi.org/10.22541/au.163525012.23548218/v1
Autor:
Yingnan Liu, Biao Kong, Meng Gao, Runhao Zhang, Qi Wan, Pu Chen, Tong Wu, Qingdong Chai, Jingchen Gao, Jiangdong Sun, Kang Liang, Lei Xie
Publikováno v:
ACS applied materialsinterfaces. 13(42)
Hypoxia, induced by inadequate oxygen supply, is a key indication of various major illnesses, which necessitates the need to develop new nanoprobes capable of sensing hypoxia environments for the targeted system monitoring and drug delivery. Herein,
Autor:
Adam C. Midgley, Siyuan Chen, Di Tang, Deling Kong, Jingchen Gao, Jie Shi, Lina Wang, Shufang Wang, Li Jiang, Lin Zhang, Xiangyun Zhang
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 107:2040-2049
The bioinert characteristic of polycaprolactone (PCL) remains a major defect when using PCL-based materials as small-diameter vascular grafts for implantation in vivo. To improve the hydrophilicity, cytocompatibility, and biodegradation of PCL vascul
Publikováno v:
Journal of materials chemistry. B. 3(47)
Thrombosis and neointimal hyperplasia are the main causes for the failure of small diameter vascular grafts, and a complete and functional endothelium is essential in preventing these problems. Therefore, grafts that could be endothelialized rapidly