Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Jingchen Feng"'
Autor:
Jihan Kim, Jingchen Feng, Christopher A. R. Jones, Xiaoming Mao, Leonard M. Sander, Herbert Levine, Bo Sun
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
The structure and mechanics of tissues is constantly perturbed by endogenous forces originated from cells. Here the authors show that 3D collagen gels, major components of connective tissues and extracellular matrix, are significantly and irreversibl
Externí odkaz:
https://doaj.org/article/75282c6ce4444252a75d97de6f19645f
Autor:
Weiyue Ji, Handuo Shi, Haoqian Zhang, Rui Sun, Jingyi Xi, Dingqiao Wen, Jingchen Feng, Yiwei Chen, Xiao Qin, Yanrong Ma, Wenhan Luo, Linna Deng, Hanchi Lin, Ruofan Yu, Qi Ouyang
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57482 (2013)
The concept of microbial consortia is of great attractiveness in synthetic biology. Despite of all its benefits, however, there are still problems remaining for large-scaled multicellular gene circuits, for example, how to reliably design and distrib
Externí odkaz:
https://doaj.org/article/43c9acc803a345cb908a1a442a25a5a4
Autor:
Fred C. MacKintosh, Jingchen Feng, Anne van Oosten, Herbert Levine, Paul A. Janmey, Jordan Shivers
Publikováno v:
Proc Natl Acad Sci U S A
Tissues commonly consist of cells embedded within a fibrous biopolymer network. Whereas cell-free reconstituted biopolymer networks typically soften under applied uniaxial compression, various tissues, including liver, brain, and fat, have been obser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee031b25964e8ee1d25d12814c02d6a
https://doi.org/10.1073/pnas.2003037117
https://doi.org/10.1073/pnas.2003037117
Publikováno v:
Soft matter. 15(24)
Mechanical properties of the substrate play a vital role in cell motility. In particular, cells have been shown to migrate along aligned fibers in the substrate (contact guidance) and up stiffness gradients (durotaxis). Here we present a simple mecha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd9ed465638323681190f47168799f4
https://pubmed.ncbi.nlm.nih.gov/31161163
https://pubmed.ncbi.nlm.nih.gov/31161163
Publikováno v:
Soft Matter
Networks of filamentous actin (F-actin) are important for the mechanics of most animal cells. These cytoskeletal networks are highly dynamic, with a variety of actin-associated proteins that control cross-linking, polymerization and force generation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701b573c08229c59437cd7de6879c828
http://arxiv.org/abs/1905.08346
http://arxiv.org/abs/1905.08346
Publikováno v:
BMC Systems Biology
BMC Systems Biology, Vol 12, Iss 1, Pp 1-12 (2018)
BMC Systems Biology, Vol 12, Iss 1, Pp 1-12 (2018)
MotivationOne of the major challenges in traditional mathematical modeling of gene regulatory circuits is the insufficient knowledge of kinetic parameters. These parameters are often inferred from existing experimental data and/or educated guesses, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9066cc70f77edbb1136263a8441863bc
http://europepmc.org/articles/PMC6006707
http://europepmc.org/articles/PMC6006707
Mechanical properties of the substrate plays a vital role in cell motility. Cells are shown to migrate up stiffness gradient (durotaxis) and along aligned fibers in the substrate (contact guidance). Here we present a simple mechanical model for cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5398dbf033fa053855a65e35f259653
https://doi.org/10.1101/320705
https://doi.org/10.1101/320705
Supplementary algorithmic details and user guide of RACIPE and supplementary figures. (DOCX 6198 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5c9d6a6ea4da1b887c80b4e71641b6
Hydrogels of semiflexible biopolymers such as collagen have been shown to contract axially under shear strain, in contrast to the axial dilation observed for most elastic materials. Recent work has shown that this behavior can be understood in terms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16466cbd58c46fe5a55b4938f8536a1a
http://arxiv.org/abs/1711.00522
http://arxiv.org/abs/1711.00522
Publikováno v:
Physical review. E. 96(1-1)
Cells exhibit qualitatively different behaviors on substrates with different rigidities. The fact that cells are more polarized on the stiffer substrate motivates us to construct a two-dimensional cell with the distribution of focal adhesions depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8163e2a72a45a4577ad25d1bf78a8445
https://pubmed.ncbi.nlm.nih.gov/29347081
https://pubmed.ncbi.nlm.nih.gov/29347081