Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jingbo Qin"'
Autor:
Xiaohui Chen, Meichun Gao, Yongzhen Xia, Xin Wang, Jingbo Qin, Hongying He, Weirong Liu, Xiaowei Zhang, Shuangzhou Peng, Zhiping Zeng, Ying Su, Xiaokun Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1204-1221 (2024)
The orphan nuclear receptor Nur77 is a critical regulator of the survival and death of tumor cells. The pro-death effect of Nur77 can be regulated by its interaction with Bcl-2, resulting in conversion of Bcl-2 from a survival to killer. As Bcl-2 is
Externí odkaz:
https://doaj.org/article/9099f275d897481e906a2e2142a26210
Autor:
Jun Wu, Hongyu Hu, Mingtao Ao, Zhenzhen Cui, Xiaoping Zhou, Jingbo Qin, Yafei Guo, Jingwei Chen, Yuhua Xue, Meijuan Fang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1435-1452 (2021)
This study describes the synthesis and vacuole-inducing activity of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carbohydrazide derivatives, including five potent derivatives 12c, 12 g, 12i, 12n, and 12A that exhibit excellent vacuole-induci
Externí odkaz:
https://doaj.org/article/93b372747c5d480fad35471d60ddee4f
Autor:
Jingbo Qin, Jie Liu, Chunxiao Wu, Jianwen Xu, Bowen Tang, Kaiqiang Guo, Xiaohui Chen, Weihao Liu, Tong Wu, Hu Zhou, Meijuan Fang, Zhen Wu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 880-896 (2020)
Abnormal alterations in the expression and biological function of retinoid X receptor alpha (RXRα) have a key role in the development of cancer. Potential modulators of RXRα as anticancer agents are explored in growing numbers of studies. A series
Externí odkaz:
https://doaj.org/article/ed6d1872578c469fbbcd730010790f1f
Autor:
Lingru Li, Yue Meng, Ji Wang, Ying Zhang, Yong Zeng, Huiqun Xiao, Jiangming He, Zhenquan Liu, Shujuan Hou, Tianxing Li, Jingbo Qin, Yini Fang, Wenqian Guo, Li'an Liu, Hui Luo, Yingshuai Li, Yanfei Zheng, Qi Wang
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
Objective: The objective of this study was to investigate how knowledge and practice of coronavirus disease 2019 (COVID-19) prevention measures affected concerns about returning to work among supermarket staff. Attitudes about the ability of traditio
Externí odkaz:
https://doaj.org/article/5753b8fafd564a7eaf5480f2c79f0842
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Allergic asthma is a stubborn chronic inflammatory disease, and is considered a co-result of various immune cells, especially mast cells, eosinophils and T lymphocytes. At present, the treatment methods of allergic asthma are limited and the side eff
Externí odkaz:
https://doaj.org/article/49f768770dff48aeb2b66c756cef5a1d
Autor:
Zhijian Kuang, Kaiqiang Guo, Chaojie Wang, Mengxue Jiang, Qiaoqiong Wu, Hu guosheng, Yin Cao, Mingtao Ao, Mingfeng Huang, Jingbo Qin, Taige Zhao, Sheng Lu, Cuiling Sun, Mingyu Li, Tong Wu, Wen Liu, Meijuan Fang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcafffd38bcd5b6fe09347f732cf422b
https://doi.org/10.2139/ssrn.4391581
https://doi.org/10.2139/ssrn.4391581
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 36
Breast cancer is becoming a common life-threatening disease, especially in women, along with higher incidence and mortality. MicroRNA (miR)-506 was reported to participate in breast cancer progression, while the role of miR-506 in breast cancer-induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a388d9a1b051414448e256e3aa9db3
https://doi.org/10.1002/jbt.23156
https://doi.org/10.1002/jbt.23156
Autor:
Jingbo Qin, Xiaohui Chen, Weihao Liu, Jun Chen, Weirong Liu, Yongzhen Xia, Zhehui Li, Mingyu Li, Shaojuan Wang, Quan Yuan, Yingkun Qiu, Zhen Wu, Meijuan Fang
Publikováno v:
European Journal of Medicinal Chemistry. 244:114849
Encouraged by our previous findings and in continuation of our ongoing study project in designing and synthesis of novel Nur77-targeting anti-cancer agents, a series of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole-2-carboxamide derivatives wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bee52553d5aaad33983f432fbd3a45
https://doi.org/10.1016/j.ejmech.2022.114849
https://doi.org/10.1016/j.ejmech.2022.114849
Autor:
Mingsheng Lyu, Yahui Wang, Qiuyi Chen, Jingbo Qin, Dan Hou, Shuaiyang Huang, Dongmei Shao, Xuefeng Gong, Guirui Huang, Shiyu Zhang, Zhijie Zhang, Hongsheng Cui
Publikováno v:
Drug design, development and therapy. 16
Mingsheng Lyu,1,* Yahui Wang,2,* Qiuyi Chen,1,* Jingbo Qin,3 Dan Hou,1 Shuaiyang Huang,1 Dongmei Shao,1 Xuefeng Gong,4 Guirui Huang,1 Shiyu Zhang,1 Zhijie Zhang,1 Hongsheng Cui1 1Department of Respiratory, The Third Affiliated Hospital, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd43c67f7a8bf3c627762d15388a577
https://pubmed.ncbi.nlm.nih.gov/35386850
https://pubmed.ncbi.nlm.nih.gov/35386850
Autor:
Zhihuan Liao, Shuaidong Huo, Xing-Jie Liang, Shouwen Zhang, Ningqiang Gong, Peter S. Timashev, Jingbo Qin
Publikováno v:
Nanoscale. 13(15)
Mitochondria play critical roles in the regulation of the proliferation and apoptosis of cancerous cells. Nanosystems for targeted delivery of cargos to mitochondria for cancer treatment have attracted increasing attention in the past few years. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35576426f00f159df7ef3359593d7035
https://pubmed.ncbi.nlm.nih.gov/33889907
https://pubmed.ncbi.nlm.nih.gov/33889907