Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jingbo Qie"'
Autor:
Jingbo Qie, Yang Liu, Yunzhi Wang, Fan Zhang, Zhaoyu Qin, Sha Tian, Mingwei Liu, Kai Li, Wenhao Shi, Lei Song, Mingjun Sun, Yexin Tong, Ping Hu, Tao Gong, Xiaqiong Wang, Yi Huang, Bolong Lin, Xuesen Zheng, Rongbin Zhou, Jie Lv, Changsheng Du, Yi Wang, Jun Qin, Wenjun Yang, Fuchu He, Chen Ding
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-23 (2022)
Macrophage is located in different tissue to serve diverse functions. Here the authors use mass spectrometry and bulk RNA-sequencing to profile 11 mouse macrophage populations from 8 tissues, and combine their de novo data with public datasets to rep
Externí odkaz:
https://doaj.org/article/42aa5c3f294d4fc78c544a437d316019
Autor:
Yexin Tong, Mingjun Sun, Lingli Chen, Yunzhi Wang, Yan Li, Lingling Li, Xuan Zhang, Yumeng Cai, Jingbo Qie, Yanrui Pang, Ziyan Xu, Jiangyan Zhao, Xiaolei Zhang, Yang Liu, Sha Tian, Zhaoyu Qin, Jinwen Feng, Fan Zhang, Jiajun Zhu, Yifan Xu, Wenhui Lou, Yuan Ji, Jianyuan Zhao, Fuchu He, Yingyong Hou, Chen Ding
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-47 (2022)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with poor prognosis. Proteogenomic characterization and integrative proteomic analysis provide a functional context to annotate genomic abnormalities with prognostic
Externí odkaz:
https://doaj.org/article/3aedf2d3f1e44ba79edc3fe33867e9b0
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/040036f3397f47538061431c2fc6db85
Autor:
Qi Song, Ye Yang, Dongxian Jiang, Zhaoyu Qin, Chen Xu, Haixing Wang, Jie Huang, Lingli Chen, Rongkui Luo, Xiaolei Zhang, Yufeng Huang, Lei Xu, Zixiang Yu, Subei Tan, Minying Deng, Ruqun Xue, Jingbo Qie, Kai Li, Yanan Yin, Xuetong Yue, Xiaogang Sun, Jieakesu Su, Fuchu He, Chen Ding, Yingyong Hou
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
Squamous cell carcinomas are an aggressive cancer type which can occur in multiple organ systems. Here, the authors analyse the proteome of SCC cancers from 17 organs and show commonly dysregulated proteins independent of location.
Externí odkaz:
https://doaj.org/article/05d0671cbe88464bab2dc69a85f38421
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
As one of the most malignant cancer, hepatocellular carcinoma (HCC) has a complex ecosystem featured by high heterogeneity. Cell crosstalk is demonstrated to be critical for HCC development. However, the cell communication orchestration in HCC remain
Externí odkaz:
https://doaj.org/article/8a4ab36916bd40778b8a3dd9d76267e2
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Antibiotic resistance (AMR) has always been a hot topic all over the world and its mechanisms are varied and complicated. Previous evidence revealed the metabolic slowdown in resistant bacteria, suggesting the important role of metabolism in antibiot
Externí odkaz:
https://doaj.org/article/4c97951ee7664154a9659ea3ec7728fa
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Intestinal barrier dysfunction is characterized by increased intestinal permeability to lumen endotoxin, showing remarkable predisposition to immune enteropathy, and colorectal cancer tumor necrosis factor (TNF)-α is associated with this pathologica
Externí odkaz:
https://doaj.org/article/8c885a01b97e42fd97bd68f687c51a05
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Combined inhibition of programmed death-ligand 1 (PD-L1) and transforming growth factor-β (TGF-β) displayed additive anti-tumor response in a subgroup of cancer patients, highlighting the importance of understanding the multifaceted roles of TGF-β
Externí odkaz:
https://doaj.org/article/730e2daa2c824b4cbc7144afbf98e082
Autor:
Yunzhi Wang, Lei Song, Mingwei Liu, Rui Ge, Quan Zhou, Wanlin Liu, Ruiyang Li, Jingbo Qie, Bei Zhen, Yi Wang, Fuchu He, Jun Qin, Chen Ding
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
As a circadian organ, liver functions are regulated by circadian clock. Here, the authors present a comprehensive proteomics landscape of the mouse liver, including transcription factor binding profiles, phosphorylation and ubiquitylation patterns, n
Externí odkaz:
https://doaj.org/article/c2746023e79f426285a71b856be331b7
Autor:
Yuedi Wang, Yiyuan Gao, Congyi Niu, Bo Wang, Shushu Zhao, Gils Roex, Jiawen Qian, Jingbo Qie, Lin Chen, Chenhe Yi, Sébastien Anguille, Jie Liu, Feifei Luo, Yiwei Chu
Publikováno v:
Cancer immunology and immunotherapy
Chimeric antigen receptor (CAR) T-cell therapy achieves great success for hematological malignancies. However, clinical trials have revealed some limitations in both improving the efficacy and reducing the relapse, which calls for innovative strategi