Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jing-ying Jia"'
Autor:
Yu-zhou Gui, Wei Wang, Qing-qing Wu, Qi-chen Ding, Hong-jie Qian, Qiu-bei Lu, Ying-jun Zhang, Yu-lei Zhuang, Li Deng, Ying-lin Zuo, Lin Luo, Jing-ying Jia
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Heart failure is the most costly cardiovascular disorder. New treatments are urgently needed. This study aims to evaluate the safety, pharmacokinetics, and pharmacodynamic profile of HEC95468, a soluble guanylate cyclase (sGC) stimulator, in healthy
Externí odkaz:
https://doaj.org/article/471eb2450690481191e91200a2f0c4db
Autor:
Yu-Zhou Gui, Xue-Ning Li, Jing-Xin Li, Ming-Yun Shen, Mei-Wei Zhang, Ye Cao, Hong-Rong Xu, Hui Li, Jie Cheng, Liang Pan, Ying-Lei Yi, Li-Yu Liang, Cheng-Yin Yu, Gang-Yi Liu, Chen Yu, Bi-Jie Hu, Feng-Cai Zhu, Fei Liang, Haifa Shen, Jing-Ying Jia, Hang-Wen Li, Jian Zhou, Jia Fan
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104586- (2023)
Summary: Background: We assessed the safety and immunogenicity of a core–shell structured lipopolyplex (LPP) based COVID-19 mRNA vaccine, SW-BIC-213, as a heterologous booster in healthy adults. Methods: We conducted an open-labeled, two-centered,
Externí odkaz:
https://doaj.org/article/8a8a7fea066c4164a25277ccaada978c
Autor:
Hong-Jie, Qian, Yu, Wang, Meng-Qi, Zhang, Yuan-Chao, Xie, Qing-Qing, Wu, Li-Yu, Liang, Ye, Cao, Hua-Qing, Duan, Guang-Hui, Tian, Juan, Ma, Zhuo-Bing, Zhang, Ning, Li, Jing-Ying, Jia, Jing, Zhang, Haji Akber, Aisa, Jing-Shan, Shen, Chen, Yu, Hua-Liang, Jiang, Wen-Hong, Zhang, Zhen, Wang, Gang-Yi, Liu
Publikováno v:
Acta Pharmacologica Sinica. 43:3130-3138
VV116 (JT001) is an oral drug candidate of nucleoside analog against SARS-CoV-2. The purpose of the three phase I studies was to evaluate the safety, tolerability, and pharmacokinetics of single and multiple ascending oral doses of VV116 in healthy s
Autor:
Jingquan Li, Hui Wang, Chen Yu, Xiaohua Duan, Ruiai Chu, Jing-ying Jia, Mian Li, Jun-hua Han, Peizhan Chen
Publikováno v:
Acta pharmacologica Sinica. 37(11)
To examine the biological consequences and demographic factors that might affect the pharmacokinetics of vitamin D3 after a single high dose intervention in a young Chinese population with vitamin D insufficiency status. A total of 28 young subjects
Autor:
Zhi-bing, Xu, Wei-dong, Wang, Li-fen, Zhang, Jun, Li, Yi, Wang, Xi-xiang, Xi, Jie, Zhu, Jin-miao, Ma, Jing-ying, Jia, Li-wei, Zhang, Ren-yue, Gu
Publikováno v:
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 35(9)
To explore targets of Chinese herbal medicine at cellular and molecular leve1s through an experimental study on Yinxingye Capsule (YC) intervening vascular endothelial cell apoptoeis of hyperhornocysteinemia (HHcy) rats.The HHcy model was prepared in
Autor:
Chuan Lu, Chen Yu, Meng-qi Zhang, Yulin Qi, Gangyi Liu, Li-ping Weng, Shuijun Li, Yan-mei Liu, Yun Liu, Jing Ying Jia
Publikováno v:
Clinical Therapeutics. 32:1387-1395
Losartan is a nonpeptide angiotensin II receptor antagonist used as an antihypertensive agent. The relative bioavailability of a newly developed tablet compared with an established branded formulation has not been reported in a Chinese population.To
Autor:
Jing-Ying Jia, S. W. Annie Bligh, Rui An, Xinhong Wang, Shuang Wang, Jin Yuan, Ying Wang, Yue-ming Ma, Shui-Jun Li
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
A simple and sensitive method for simultaneous determination of seven active constituents, jatrorrhizine, berberine, coptisine, palmatine, evodiamine, rutacarpine and paeoniflorin, from a Chinese medicine Wuji Pill in rat plasma was developed based o
Autor:
Meng-Qi, Zhang, Jing-Ying, Jia, Chuan, Lu, Gang-Yi, Liu, Cheng-Yin, Yu, Yu-Zhou, Gui, Yun, Liu, Yan-Mei, Liu, Wei, Wang, Shui-Jun, Li, Chen, Yu
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 45(6)
A simple, reliable and sensitive liquid chromatography-isotope dilution mass spectrometry (LC-ID/MS) was developed and validated for quantification of olanzapine in human plasma. Plasma samples (50 microL) were extracted with tert-butyl methyl ether
Publikováno v:
Acta pharmacologica Sinica. 25(11)
To develop a specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the pharmacokinetic study of magnesium lithospermate B (MLB), and study the pharmacokinetics of MLB after i.v. administration in beagle dogs.Each beagle dog wa
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 38(3)
To establish an HPLC-fluorescent spectrometric method for the determination of mexiletine hydrochloride in plasma after derivatization with fluram.Fluram acetone solution was added to the deproteinized plasma with acetone to obtain the derivative of