Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jing-kai Gu"'
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 22190-22204 (2015)
This study aimed at investigating the possible mechanisms of hepatic protective activity of Cichorium intybus L. (chicory) in acute liver injury. Pathological observation, reactive oxygen species (ROS) detection and measurements of biochemical indexe
Externí odkaz:
https://doaj.org/article/acc9635a17f64c79805bf85b944934a6
Autor:
Xiao-Jiao Li, Yan-Tong Sun, Lei Yin, Xue-Ju Zhang, Yan Yang, J. Paul Fawcett, Yi-Min Cui, Jing-Kai Gu
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 3, Iss 1, Pp 1-8 (2013)
A rapid and sensitive method based on liquid chromatographyâtandem mass spectrometry (LCâMS/MS) for the determination of a novel anticoagulant peptide bivalirudin in human plasma has been developed and validated. Plasma samples were precipitated pr
Externí odkaz:
https://doaj.org/article/da44d5eac1054072a08a31fe4b4636d3
Autor:
Hai-yan Li, Xiang-yong Cui, Feng Gao, Peter York, Qun Shao, Xian-zhen Yin, Tao Guo, Zhen Guo, Jing-kai Gu, Ji-wen Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 1, Iss 2, Pp 106-114 (2011)
It is essential to develop effective methods for the quality control of the traditional medicine with multiple components. However, few researches on the quality control have been conducted to interpret the holistic characteristics of the traditional
Externí odkaz:
https://doaj.org/article/7ee7ffad087a4c56a150529ac456fccc
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 1, Iss 1, Pp 40-45 (2011)
A rapid and sensitive method based on high-performance liquid chromatography–tandem mass spectrometry (LC–MS/MS) has been developed for the determination of repaglinide in human plasma. The analyte and internal standard (I.S.), diazepam, were ext
Externí odkaz:
https://doaj.org/article/b5f12487cbea47e683b5bd505321ed8d
Autor:
Jie Cheng, Zhao Yang, Xiao-Yan Ge, Ming-Xin Gao, Ran Meng, Xin Xu, Yu-Qi Zhang, Rui-Zhe Li, Jing-Yu Lin, Zhao-Mei Tian, Jin Wang, Shang-Lei Ning, Yun-Fei Xu, Fan Yang, Jing-Kai Gu, Jin-Peng Sun, Xiao Yu
Publikováno v:
Cell Metabolism. 34:240-255.e10
Along with functionally intact insulin, diabetes-associated insulin peptides are secreted by β cells. By screening the expression and functional characterization of olfactory receptors (ORs) in pancreatic islets, we identified Olfr109 as the recepto
Autor:
Chao, Hu, Jing, Zheng, Jia, Miao, Fang, Liu, Ting-Ting, Hu, Jing-Kai, Gu, Shi-Qing, Shu, Ying, Wang, Xiao-Hong, Zhu, Mao-Zhi, Liang
Publikováno v:
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 49(1)
To compared the differences in pharmacokinetics of phosphate retagliptin tablets in patients with varying degrees of renal dysfunction.A total of 32 patients were categorized into five groups according to their renal function: normal,mild dysfunction
Autor:
Xiao-Cong Zuo, Chengxian Guo, Yun Kuang, Lu Huang, Qi Pei, Jing-kai Gu, J Ding, Shi-Kun Liu, Guoping Yang, Hongyi Tan, Jie Huang
Aim: Iloperidone is an atypical antipsychotic drug that is mainly metabolized by CYP2D6, CYP3A4, and cytosolic enzymes. Previous studies show that extensive and poor metabolizers of CYP2D6 exhibit different plasma concentrations of iloperidone and it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea788600d03220314bb398d2938c9041
https://doi.org/10.1038/aps.2016.96
https://doi.org/10.1038/aps.2016.96
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 9, Pp 22190-22204 (2015)
International Journal of Molecular Sciences
Volume 16
Issue 9
Pages 22190-22204
International Journal of Molecular Sciences
Volume 16
Issue 9
Pages 22190-22204
This study aimed at investigating the possible mechanisms of hepatic protective activity of Cichorium intybus L. (chicory) in acute liver injury. Pathological observation, reactive oxygen species (ROS) detection and measurements of biochemical indexe
Autor:
Su Zeng, Lu Shan Yu, Zi Zhao Yang, Miao Hao, Li Li, Hai Xing Ju, Jing Kai Gu, Hui Di Jiang, Ming Cheng Xu, Zai Jie Jim Wang
Publikováno v:
Oncotarget
// Zi-Zhao Yang 1 , Li Li 2 , Ming-Cheng Xu 1 , Hai-Xing Ju 3 , Miao Hao 4 , Jing-Kai Gu 5 , Zai-Jie Jim Wang 6 , Hui-Di Jiang 1 , Lu-Shan Yu 1 , Su Zeng 1 1 Laboratory of Pharmaceutical Analysis and Drug Metabolism, Zhejiang Province Key Laboratory
Publikováno v:
Chinese Journal of Analytical Chemistry. 42:10-15
A strategy for the absolute quantitation of metabolic enzymes in rat liver microsomes was developed based on shotgun-based proteomics approach. Rat liver microsomes were digested with trypsin, and drug metabolizing enzymes were determined by liquid c