Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Jing-hua Yang"'
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-17 (2024)
Abstract Regulated cell death (RCD) plays a crucial role in the immune microenvironment, development, and progression of hepatocellular carcinoma (HCC). However, reliable immune-related cell death signatures have not been explored. In this study, we
Externí odkaz:
https://doaj.org/article/c1aaa163d355406f8f8f1e442b7d1697
Underlying mechanisms of ketotherapy in heart failure: current evidence for clinical implementations
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Heart failure (HF) is a life-threatening cardiac syndrome characterized by high morbidity and mortality, but current anti-heart failure therapies have limited efficacy, necessitating the urgent development of new treatment drugs. Exogenous ketone sup
Externí odkaz:
https://doaj.org/article/abae7bae1b374934aa0fb5095f254228
Autor:
Jinfeng Chen, An Zhang, Anzheng Nie, Xiaoxiao Zuo, Lei Zhang, Yuxue Jiao, Lulu Wang, Yang Yang, Kun Liu, Xinli Xue, Yuanyuan Zhuang, Yansha Meng, Jing-Hua Yang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background:Stephania tetrandra has been used for treating rheumatic diseases for thousands of years in rural areas of China. Several studies have found that tetrandrine and fangchinoline can inactivate the PI3K/Akt signaling pathway by reducing the e
Externí odkaz:
https://doaj.org/article/16a611a7bf8b49a4a5b214d8dd2e9ce3
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundThe gut microbiota significantly influences the onset and progression of juvenile idiopathic arthritis (JIA) and associated uveitis (JIAU); however, the causality remains unclear. This study aims to establish a causal link between gut micro
Externí odkaz:
https://doaj.org/article/8b99fc411ac14758820102ef735710df
Autor:
Qing-Fang Han, Wen-Jia Li, Kai-Shun Hu, Jie Gao, Wen-Long Zhai, Jing-Hua Yang, Shui-Jun Zhang
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-26 (2022)
Abstract Exosomes are well-known key mediators of intercellular communication and contribute to various physiological and pathological processes. Their biogenesis involves four key steps, including cargo sorting, MVB formation and maturation, transpo
Externí odkaz:
https://doaj.org/article/dbcff47cc30746a8837228d894d065e4
Autor:
Nanqiao Liao, Zhongyuan Hu, Jinshan Miao, Xiaodi Hu, Xiaolong Lyu, Haitian Fang, Yi-Mei Zhou, Ahmed Mahmoud, Guancong Deng, Yi-Qing Meng, Kejia Zhang, Yu-Yuan Ma, Yuelin Xia, Meng Zhao, Haiyang Yang, Yong Zhao, Ling Kang, Yiming Wang, Jing-Hua Yang, Yan-Hong Zhou, Ming-Fang Zhang, Jing-Quan Yu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Genome evolution of Allium genus and genomic basis underlying the pungency flavor formation remain poorly understood. Here, the authors assemble the genome of bunching onion and conduct population genetics analyses to reveal Allium genome evolution,
Externí odkaz:
https://doaj.org/article/65e4cff940fe4aa8b05244daf8e55720
Publikováno v:
Energy Reports, Vol 8, Iss , Pp 77-86 (2022)
This paper constructs an economic dispatch model of an integrated energy system including grid, wind power, photovoltaic and energy storage devices based on combined cooling, heating and power system, and optimizes the dispatch model based on improve
Externí odkaz:
https://doaj.org/article/94a1e4988018487d878861d48df72ad9
Publikováno v:
Biomedicines, Vol 12, Iss 1, p 81 (2023)
Clinical and basic research suggests that bladder ischemia may be an independent variable in the development of lower urinary tract symptoms (LUTS). We have reported that ischemic changes in the bladder involve differential expression and post-transl
Externí odkaz:
https://doaj.org/article/10d24a0f21d24dd6a7010d0d3a24c1b9
Autor:
Li-Yuan Fan, Jing Yang, Ming-Li Li, Ruo-Yu Liu, Ying Kong, Su-Ying Duan, Guang-Yu Guo, Jing-Hua Yang, Yu-Ming Xu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Astrocytes play an important role in the pathogenesis of Alzheimer’s disease (AD). It is widely involved in energy metabolism in the brain by providing nutritional and metabolic support to neurons; however, the alteration in the metabolism of astro
Externí odkaz:
https://doaj.org/article/1c91ba64c4d24ab3b8439ab1e9a6e83f
Publikováno v:
Investigative and Clinical Urology, Vol 62, Iss 5, Pp 600-609 (2021)
Purpose: Ischemia disrupts cellular energy homeostasis. Adenosine monophosphate-activated protein kinase alpha-2 (AMPK-α2) is a subunit of AMPK that senses cellular energy deprivation and signals metabolic stress. Our goal was to examine the express
Externí odkaz:
https://doaj.org/article/44583ab80d8c4ae989492bab6e8ac458