Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jing-e Zhou"'
Autor:
Lei Sun, Jinfang Zhang, Jing-e Zhou, Jing Wang, Zhehao Wang, Shenggen Luo, Yeying Wang, Shulei Zhu, Fan Yang, Jie Tang, Wei Lu, Yiting Wang, Lei Yu, Zhiqiang Yan
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 1, Pp 100769- (2023)
The siRNA-loaded lipid nanoparticles have attracted much attention due to its significant gene silencing effect and successful marketization. However, the in vivo distribution and release of siRNA still cannot be effectively monitored. In this study,
Externí odkaz:
https://doaj.org/article/0b23e63d2eda42a7b5f14c0e2d1162f5
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 137, Iss , Pp 111339- (2021)
Chimeric antigen receptor T cells (CAR-T) immunotherapy has shown promising clinical results in the treatment of leukemia and lymphoma, but the effectiveness is limited for solid tumors. The PD-1/PD-L1 pathway is a key immunosuppressive mechanism for
Externí odkaz:
https://doaj.org/article/b46d937edbcc404b88d6f8f49e1b2964
Autor:
Hongjia Zhu, Xiaoyan Fang, Israth Jahan Tuhin, Jingwen Tan, Jing Ye, Yujie Jia, Nan Xu, Liqing Kang, Minghao Li, XiaoYan Lou, Jing-e Zhou, Yiting Wang, Zhiqiang Yan, Lei Yu
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:2261-2274
Purpose: Chimeric antigen receptor (CAR) T cell therapy has demonstrated clinical success in treating haematologic malignancies but has not been effective against solid tumours thus far. Trop2 is a tumour-related antigen broadly overexpressed on a va
Autor:
Jing-E Zhou, Lei Sun, Li Liu, Yujie Jia, Yuqiao Han, Jiaqi Shao, Jing Wang, Yiting Wang, Lei Yu, Zhiqiang Yan
Publikováno v:
Journal of Controlled Release. 343:175-186
HMGB1 is an inflammatory factor produced by macrophages after liver injury, which plays a key role in promoting NASH progression and further developing into liver fibrosis and cirrhosis. In this study, a mannose-modified HMGB1-siRNA loaded stable nuc
Autor:
Lei Sun, Jing‐e Zhou, Tengshuo Luo, Jing Wang, Liqing Kang, Yeying Wang, Shenggen Luo, Zhehao Wang, Ziyu Zhou, Jiaxi Zhu, Jiahui Yu, Lei Yu, Zhiqiang Yan
Publikováno v:
Advanced materials (Deerfield Beach, Fla.). 34(15)
The rapid evolution of cell-based theranostics has attracted extensive attention due to their unique advantages in biomedical applications. However, the inherent functions of cells alone cannot meet the needs of malignant tumor treatment. Thus endowi
Autor:
Shuyan Wen, Liewen Pang, Wenshuo Wang, Yiqing Wang, Jiechun Huang, Xiaotian Sun, Jing-E Zhou, Kai Huang, Fangrui Wang
Publikováno v:
Nanomedicine (London, England). 16(6)
Aim: To construct a long circulatory and sustained releasing H2S system and explore its protective effects on myocardial ischemia and reperfusion (I/R) injury. Materials & methods: Red blood cell (RBC) membrane-coated, diallyl trisulfide (DATS)-carry
Publikováno v:
Current Pharmaceutical Design. 23
Background: In this study, we developed a drug of IFN-α combined with pPB-SSLs, which specifically target at platelet-derived growth factor receptor-β (PDGFR-β). Aim: The aim of this study is to improve the limitations of IFN-α including insuffic