Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jing-Yuan Chooi"'
Autor:
Yunlu Jia, Jianbiao Zhou, Tze King Tan, Tae-Hoon Chung, Regina Wan Ju Wong, Jing-Yuan Chooi, Julia Sze Lynn Lim, Takaomi Sanda, Melissa Ooi, Sanjay De Mel, Cinnie Soekojo, Yongxia Chen, Enfan Zhang, Zhen Cai, Peng Shen, Jian Ruan, Wee-Joo Chng
Publikováno v:
Blood Cancer Journal, Vol 11, Iss 2, Pp 1-13 (2021)
Abstract Multiple myeloma (MM) is an aggressive plasma cell neoplasm characterized by genomic heterogeneity. Superenhancers (SEs) are defined as large clusters of enhancers in close genomic proximity, which regulate genes for maintaining cellular ide
Externí odkaz:
https://doaj.org/article/84a9518ee10c44cc91668e7428907d28
Autor:
Jianbiao Zhou, Sabrina Hui-Min Toh, Zit-Liang Chan, Jessie Yiying Quah, Jing-Yuan Chooi, Tuan Zea Tan, Phyllis S. Y. Chong, Qi Zeng, Wee-Joo Chng
Publikováno v:
Journal of Hematology & Oncology, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background Protein tyrosine phosphatase of regenerating liver 3 (PRL-3) is overexpressed in a subset of AML patients with inferior prognosis, representing an attractive therapeutic target. However, due to relatively shallow pocket of the cat
Externí odkaz:
https://doaj.org/article/57ddfe36df5c4d61aa3ae49750543f97
Autor:
Jianbiao Zhou, Chonglei Bi, Ying Qing Ching, Jing-Yuan Chooi, Xiao Lu, Jessie Yiying Quah, Sabrina Hui-Min Toh, Zit-Liang Chan, Tuan Zea Tan, Phyllis SY Chong, Wee-Joo Chng
Publikováno v:
Journal of Hematology & Oncology, Vol 10, Iss 1, Pp 1-13 (2017)
Abstract Background Current conventional chemotherapy for acute myeloid leukemia (AML) can achieve remission in over 70% of patients, but a majority of them will relapse within 5 years despite continued treatment. The relapse is postulated to be due
Externí odkaz:
https://doaj.org/article/bb8e3cff02414ed78cf8acad3518d8be
Autor:
Jianbiao Zhou, Jessie Yiying Quah, Yvonne Ng, Jing-Yuan Chooi, Sabrina Hui-Min Toh, Baohong Lin, Tuan Zea Tan, Hiroki Hosoi, Motomi Osato, Qihui Seet, A.G. Lisa Ooi, Bertil Lindmark, Mark McHale, Wee-Joo Chng
Publikováno v:
Haematologica, Vol 105, Iss 9 (2019)
Differentiation therapies achieve remarkable success in acute promyelocytic leukemia, a subtype of acute myeloid leukemia. However, excluding acute promyelocytic leukemia, clinical benefits of differentiation therapies are negligible in acute myeloid
Externí odkaz:
https://doaj.org/article/56ad0bec66f3412784863e98d8cdb0c7
Autor:
Wee Joo Chng, Peng Shen, Zhen Cai, Enfan Zhang, Julia S.L. Lim, Regina W.J. Wong, Kalpnaa Balan, Sabrina H.M. Toh, Sinan Xiong, Melissa J. Fullwood, Takaomi Sanda, Jing-Yuan Chooi, Yongxia Chen, Tae-Hoon Chung, Tze King Tan, Jianbiao Zhou, Yunlu Jia
Supplementary Table 5 shows the results of NSD2-MASPEC in KMS11 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e797f1d67ab8cec780c618567024158
https://doi.org/10.1158/0008-5472.22582469.v1
https://doi.org/10.1158/0008-5472.22582469.v1
Autor:
Wee Joo Chng, Peng Shen, Zhen Cai, Enfan Zhang, Julia S.L. Lim, Regina W.J. Wong, Kalpnaa Balan, Sabrina H.M. Toh, Sinan Xiong, Melissa J. Fullwood, Takaomi Sanda, Jing-Yuan Chooi, Yongxia Chen, Tae-Hoon Chung, Tze King Tan, Jianbiao Zhou, Yunlu Jia
Supplementary Table 2 shows 26 SE-associated genes commonly acquired in both t(4:14)-positive HMCLs and patient-derived MM sample.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f0c38237d54f425ea7a835560a97bf
https://doi.org/10.1158/0008-5472.22582478.v1
https://doi.org/10.1158/0008-5472.22582478.v1
Autor:
Wee Joo Chng, Peng Shen, Zhen Cai, Enfan Zhang, Julia S.L. Lim, Regina W.J. Wong, Kalpnaa Balan, Sabrina H.M. Toh, Sinan Xiong, Melissa J. Fullwood, Takaomi Sanda, Jing-Yuan Chooi, Yongxia Chen, Tae-Hoon Chung, Tze King Tan, Jianbiao Zhou, Yunlu Jia
Supplementary Table 1 shows the list of 4C primers applied in the Circular Chromosome Conformation Capture assay.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bffb6fa710850c6e1f2fbb5ea211ebf
https://doi.org/10.1158/0008-5472.22582481.v1
https://doi.org/10.1158/0008-5472.22582481.v1
Autor:
Wee Joo Chng, Peng Shen, Zhen Cai, Enfan Zhang, Julia S.L. Lim, Regina W.J. Wong, Kalpnaa Balan, Sabrina H.M. Toh, Sinan Xiong, Melissa J. Fullwood, Takaomi Sanda, Jing-Yuan Chooi, Yongxia Chen, Tae-Hoon Chung, Tze King Tan, Jianbiao Zhou, Yunlu Jia
Supplementary Materials and Methods shows detailed descriptions of methodology or materials and methods used in this manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac246575a8947fd21dd10152a57f427
https://doi.org/10.1158/0008-5472.22582484.v1
https://doi.org/10.1158/0008-5472.22582484.v1
Autor:
Wee Joo Chng, Peng Shen, Zhen Cai, Enfan Zhang, Julia S.L. Lim, Regina W.J. Wong, Kalpnaa Balan, Sabrina H.M. Toh, Sinan Xiong, Melissa J. Fullwood, Takaomi Sanda, Jing-Yuan Chooi, Yongxia Chen, Tae-Hoon Chung, Tze King Tan, Jianbiao Zhou, Yunlu Jia
Supplementary Figures, including Figures S1-6, and each figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03b832be439b1cf43e7c4fbab4d2cf09
https://doi.org/10.1158/0008-5472.22582487
https://doi.org/10.1158/0008-5472.22582487
Autor:
Wee Joo Chng, Peng Shen, Zhen Cai, Enfan Zhang, Julia S.L. Lim, Regina W.J. Wong, Kalpnaa Balan, Sabrina H.M. Toh, Sinan Xiong, Melissa J. Fullwood, Takaomi Sanda, Jing-Yuan Chooi, Yongxia Chen, Tae-Hoon Chung, Tze King Tan, Jianbiao Zhou, Yunlu Jia
Supplementary Table 4 shows the sequences of SE fragments inserted into pGL3 vector
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133eadc8849970895efdd29d321a18ad
https://doi.org/10.1158/0008-5472.22582472
https://doi.org/10.1158/0008-5472.22582472