Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Jing-Xu Gong"'
Autor:
Hai-Yan Zhang, Wei Xiao, Jing-Xu Gong, Cheng-Shi Jiang, Xue-dong Wang, Wen-quan Ma, Yue-Wei Guo, Wen-wen Mei, Sha-sha Ji
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 148:1807-1815
A series of new benzothiazol-based 1,3,4-oxadiazole derivatives were synthesized and evaluated for their neuroprotective effects against Aβ25–35-induced toxicity in SH-SY5Y cells. The bioassay results indicated that most of the tested compounds ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f293b4ab2b39d8e1b35459ab6456cd9a
https://doi.org/10.1007/s00706-017-1993-x
https://doi.org/10.1007/s00706-017-1993-x
Publikováno v:
Journal of Asian Natural Products Research. 19:1204-1213
The present study was designed to develop a concise synthetic route for macrolide, with the purpose of confirming the absolute configuration of natural dihydroresorcylide (1) and making it more easily accessible for biological evaluation. The absolut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::babe6e3badf260e2c79266713080c7fb
https://doi.org/10.1080/10286020.2017.1317752
https://doi.org/10.1080/10286020.2017.1317752
Autor:
Jing-Xu Gong, Jia Li, Yue-Wei Guo, Cheng-Shi Jiang, Xu-Wen Li, Li-Xin Gao, Zhong-Hua Wang, Jing-Ya Li, Li Zhang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:778-781
A series of phidianidine B derivatives were synthesized by introducing various heterocyclic rings. Their inhibitory effects on PTP1B and other PTPs (TCPTP, SHP1, SHP2 and LAR) were evaluated. A majority of them displayed significant inhibitory potenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e62109f40cba27d53e0dac17785e0c3
https://doi.org/10.1016/j.bmcl.2015.12.097
https://doi.org/10.1016/j.bmcl.2015.12.097
Publikováno v:
Helvetica Chimica Acta. 99:78-82
Methyl xestospongoate (MXS), a brominated polyunsaturalted lipid recently isolated from the Chinese marine sponge Xestospongia testudinaria, showed strong in vitro pancreatic lipase (PL) inhibitory activity. Inspired by its promising activity and pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49f0fea0c4656962b83366ce92bec6f9
https://doi.org/10.1002/hlca.201500229
https://doi.org/10.1002/hlca.201500229
Publikováno v:
Synlett. 27:391-394
The first total synthesis of xestospongenyne, a marine brominated polyunsaturated lipid with remarkable pancreatic lipase inhibitory activity (IC50 = 0.61 μM), was achieved from commercially available hept-6-yn-1-ol with 13% overall yield. This synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e1a2fe54c1657ade8c633f4ab09e093
https://doi.org/10.1055/s-0035-1560807
https://doi.org/10.1055/s-0035-1560807
Autor:
Hai-Yan Zhang, Yan Fu, Li Zhang, Zhenzhong Wang, Wei Xiao, Cheng-Shi Jiang, Jing-Xu Gong, Yue-Wei Guo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:216-220
Phidianidines (1), isolated from the marine opisthobranch mollusk Phidiana militaris, present the first example of natural products possessing an 1,2,4-oxadiazole ring system and show various bioactivities. However, the structure-activity relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::596f3953459119851458d30c648858fb
https://doi.org/10.1016/j.bmcl.2014.11.068
https://doi.org/10.1016/j.bmcl.2014.11.068
Publikováno v:
Organic Letters
Organic Letters, American Chemical Society, 2017, 19 (3), pp.714-717. ⟨10.1021/acs.orglett.6b03892⟩
Organic Letters, American Chemical Society, 2017, 19 (3), pp.714-717. ⟨10.1021/acs.orglett.6b03892⟩
International audience; The first total synthesis of a marine derived polyacetylene, distaminolyne A, and its enantiomer were achieved from the commercially available undec-10-en-1-ol. A key proline-catalyzed asymmetric α-aminooxylation of an aldehy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d7dcf6281c34a3aed0eb5c141253cf5
https://hal-polytechnique.archives-ouvertes.fr/hal-02090748
https://hal-polytechnique.archives-ouvertes.fr/hal-02090748
A series of novel thiazino[3,2-a]benzimidazole derivatives synthesized by cyclization of (R)-2-(chloromethyl)oxirane with benzimidazole-2-thiol followed by reacted with benzyl bromides in high yield under milder conditions. The molecular structures o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3994114969735da825ef6e752552d20
Publikováno v:
Steroids. 75:1153-1163
A series of novel methyl spongoate (1) analogs has been synthesized and evaluated for their in vitro cytotoxic properties. It was found that the nature of the C-20 side chain had significant effects on their bioactivities and some analogs showed high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67180d372b82f5817988c5b8446d674
https://doi.org/10.1016/j.steroids.2010.08.002
https://doi.org/10.1016/j.steroids.2010.08.002
Autor:
Feng Wang, Wei Xiong, Qiao Feng Tao, Yi Hang Wu, Yu Zhao, Jing Xu Gong, Jia Qu, Xiao Kun Li, Leixiang Yang, Ke Xin Huang, Joachim Stöckigt
Publikováno v:
Chinese Chemical Letters. 20:1030-1033
Twelve 23-esterified silybin derivatives with different patterns of substituents such as aromatic and aliphatic groups ( 1 – 12 ) were designed and synthesized. The antioxidative properties of these compounds were evaluated. The modified silybin an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec5fdd6e178337c69a20b18825c71fdd
https://doi.org/10.1016/j.cclet.2009.05.009
https://doi.org/10.1016/j.cclet.2009.05.009