Zobrazeno 1 - 2
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pro vyhledávání: '"Jing-Nan Xiang"'
Publikováno v:
Biochemical and Biophysical Research Communications. 426:324-329
Endoplasmic reticulum (ER) stress is considered as a key factor in free fatty acid (FFA)-induced apoptosis. ERp46, a new member of the thioredoxin family, is highly expressed in pancreatic β-cells and plays an important role in glucose toxicity. In
Publikováno v:
Biochemical and biophysical research communications. 421(4)
Chronic exposure to high concentrations of saturated fatty acids, such as palmitic acid (PA), leads to apoptosis of pancreatic β-cells through the activation of the c-Jun N-terminal kinase (JNK) signaling pathway. This study of β-cell lipoapoptosis