Zobrazeno 1 - 6
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pro vyhledávání: '"Jing-Kao Yu"'
Publikováno v:
Neuroscience Research. 61:390-397
Glial cell line-derived neurotrophic factor (GDNF) exerts its biological effects via a multi-component receptor system including the ligand binding receptor – GDNF family receptor-alpha1 (GFRα1) and the signaling receptor – RET tyrosine kinase.
Publikováno v:
The Journal of Comparative Neurology. 509:203-210
Glial cell line-derived neurotrophic factor (GDNF) is a potent neurotrophic factor for the substantia nigra (SN) dopamine (DA) neurons. The transmembrane signaling of GDNF is mediated by a unique receptor system, including the ligand binding receptor
Publikováno v:
Acta Pharmacologica Sinica. 28:166-172
Aim: To explore the intracellular mechanisms underlying the survival/differentiation effect of the glial cell line-derived neurotrophic factor (GDNF) on dopamine (DA) cells. Methods: Midbrain slice culture and primary cell culture were established, a
Autor:
Jing Chen, Meiying Liu, Yu Sun, Ting Wang, Hong-Jun Wang, Xiahong Xu, Honghua Yuan, Zhengquan Yu, Jing-Kao Yu, Hongyan Niu, Dianshuai Gao, Xiangui Huang, Junping Cao
Publikováno v:
Brain research. 1437
Glial cell line-derived neurotrophic factor (GDNF) is a potent protective factor for dopaminergic (DA) neurons, but the signaling mechanisms underlying the effect of GDNF on these neurons remain obscure. Here, both our in vivo and in vitro studies de
Publikováno v:
European journal of pharmacology. 595(1-3)
Calbindin-D28K is a calcium-binding protein in neuronal cytoplasm, which has the capability to protect neurons from degeneration. It was reported that glial cell line-derived neurotrophic factor (GDNF) increased calbindin-D28K expression in dopaminer
Publikováno v:
Brain research bulletin. 76(5)
Glial cell line-derived neurotrophic factor (GDNF) can exert neuroprotective effects on the substantia nigra pars compacta (SNc) dopaminergic (DA) neurons that are undergoing degeneration in Parkinson's disease (PD). In an attempt to investigate the