Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jing-Jun Nie"'
Autor:
Jing-Jun Nie, Bowen Zhang, Peng Luo, Maoguo Luo, Yuwen Luo, Jingjing Cao, Honggang Wang, Jianping Mao, Yonggang Xing, Weifeng Liu, Yuning Cheng, Renxian Wang, Yajun Liu, Xinbao Wu, Xieyuan Jiang, Xiaoguang Cheng, Chi Zhang, Da-Fu Chen
Publikováno v:
Bioactive Materials, Vol 38, Iss , Pp 455-471 (2024)
Osteosarcoma is the most common malignant bone tumor without efficient management for improving 5-year event-free survival. Immunotherapy is also limited due to its highly immunosuppressive tumor microenvironment (TME). Pore-forming gasdermins (GSDMs
Externí odkaz:
https://doaj.org/article/edb31512544f4ad5a181b63aa3200040
Autor:
Pei-Lin Li, Da-Fu Chen, Xiao-Tong Li, Rui-Cong Hao, Zhi-Dong Zhao, Zhi-Ling Li, Bo-Feng Yin, Jie Tang, Yu-Wen Luo, Chu-Tse Wu, Jing-Jun Nie, Heng Zhu
Publikováno v:
Bioactive Materials, Vol 34, Iss , Pp 204-220 (2024)
Skeletal stem cells (SSC) have gained attentions as candidates for the treatment of osteoarthritis due to their osteochondrogenic capacity. However, the immunomodulatory properties of SSC, especially under delivery operations, have been largely ignor
Externí odkaz:
https://doaj.org/article/93e7148b9e5047eca8e330ca5c368181
Autor:
Dafu Chen, Chengyue Lei, Weifeng Liu, Meiyu Shao, Meizhou Sun, Jianxun Guo, Jingjing Cao, Jing-Jun Nie, Peng Luo, Yuwen Luo, Bingran Yu, Renxian Wang, Shun Duan, Fu-Jian Xu
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 376-385 (2023)
miRNAs are important regulators of gene expression and play key roles in the development of cancer, including osteosarcoma. During the development of osteosarcoma, the expression of miR-22 is significantly downregulated, making miR-22 as a promising
Externí odkaz:
https://doaj.org/article/d71c6954a0354392af967a141fd0de0b
Autor:
Guanping He, Jing-Jun Nie, Xiao Liu, Zihao Ding, Peng Luo, Yu Liu, Bo-Wen Zhang, Renxian Wang, Xiaoguang Liu, Yong Hai, Da-Fu Chen
Publikováno v:
Bioactive Materials, Vol 19, Iss , Pp 690-702 (2023)
Osteosarcoma (OS) therapy faces many challenges, especially the poor survival rate once metastasis occurs. Therefore, it is crucial to explore new OS treatment strategies that can efficiently inhibit OS metastasis. Bioactive nanoparticles such as zin
Externí odkaz:
https://doaj.org/article/6ff068c1ddec44bfae84907535621401
Autor:
Yuyang Sun, Ben Wan, Renxian Wang, Bowen Zhang, Peng Luo, Diaodiao Wang, Jing-Jun Nie, Dafu Chen, Xinbao Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Treatment of bone defects remains a challenge in the clinic. Artificial bone grafts are the most promising alternative to autologous bone grafting. However, one of the limiting factors of artificial bone grafts is the limited means of regulating stem
Externí odkaz:
https://doaj.org/article/e007ec8570dc4be5a119f9605c644eed
Autor:
Chen Xu, Yanzhenzi Zhang, Ke Xu, Jing-Jun Nie, Bingran Yu, Sijin Li, Gang Cheng, Yulin Li, Jie Du, Fu-Jian Xu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Thoracic aortic dissection has a high fatality rate and no effective treatment. Here, the authors develop cationic nanoparticles for the delivery of miR-145 and show that they stabilize vascular structures and prevent further deterioration of the aor
Externí odkaz:
https://doaj.org/article/f7cf82f1599a4b6b86b79b2f7774664c
Autor:
Peng-Fei Cai, Jun Li, Xin-Bao Wu, Zhao-Yang Li, Jie Shen, Jing-Jun Nie, Zhen-Duo Cui, Da-Fu Chen, Yan-Qin Liang, Sheng-Li Zhu, Shui-Lin Wu
Publikováno v:
Rare Metals. 41:4138-4148
Autor:
Da-Fu Chen, Bo-Wen Zhang, Jingjing Cao, Honggang Wang, Peng Luo, Weifeng Liu, Xiaohui Niu, Renxian Wang, Jing-Jun Nie
Publikováno v:
Biomaterials science. 10(11)
Osteosarcoma, a malignant bone tumor that usually occurs in children and adolescents, has a high rate of death and disability, bringing great pains to society and families. Improving treatment approaches for osteosarcoma patients remains a constant a
Autor:
Guanping He, Jing-Jun Nie, Xiao Liu, Zihao Ding, Peng Luo, Yu Liu, Bo-Wen Zhang, Renxian Wang, Xiaoguang Liu, Yong Hai, Da-Fu Chen
Publikováno v:
Bioactive materials. 19
Osteosarcoma (OS) therapy faces many challenges, especially the poor survival rate once metastasis occurs. Therefore, it is crucial to explore new OS treatment strategies that can efficiently inhibit OS metastasis. Bioactive nanoparticles such as zin
Autor:
Jing-Jun Nie, Kai Zhang, Bingran Yu, Dan Yu, Siyuan Liu, Wenting Hu, Na Zhang, Zhen-Gang Wang, Fu-Jian Xu
Publikováno v:
ACS Materials Letters. 2:550-556
Development of novel concepts to construct drug vehicles for efficient encapsulation of hydrophobic drugs and targeted therapy is highly desirable to biomedical science. It remains a challenge to c...