Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jing-Hao Fan"'
Autor:
Jing Hao Fan, Gui Ling Fan, Ping Yuan, Fu An Deng, Ling Shan Liu, Xiang Zhou, Xi Yong Yu, Hong Cheng, Shi Ying Li
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Hypoxia is a common feature for most malignant tumors, which was also closely related to the oxygen-dependent photodynamic therapy. Based on Förster resonance energy transfer (FRET), a smart nanoprobe (designated as H-Probe) was designed in this pap
Externí odkaz:
https://doaj.org/article/5cd709a80501466e8168ee7a46d16229
Autor:
Jing-Hao Fan, Hong Cheng, Lin-Ping Zhao, Shi-Ying Li, Rong-Rong Zheng, Gui-Ling Fan, Xi-Yong Yu, Xiao-Zhong Qiu, Xian-Zheng Zhang
Publikováno v:
Biomaterials. 211:14-24
Targeted delivery of the drug to its therapeutically active site with low immunogenicity and system toxicity is critical for optimal tumor therapy. In this paper, exosomes as naturally-derived nano-sized membrane vesicles are engineered by chimeric p
Autor:
Xiang Zhou, Fu An Deng, Shi-Ying Li, Ping Yuan, Xi Yong Yu, Jing Hao Fan, Ling Shan Liu, Gui Ling Fan, Hong Cheng
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Frontiers in Chemistry
Frontiers in Chemistry
Hypoxia is a common feature for most malignant tumors, which was also closely related to the oxygen-dependent photodynamic therapy. Based on Forster resonance energy transfer (FRET), a smart nanoprobe (designated as H-Probe) was designed in this pape
Autor:
Gui-Ling Fan, Yonghua Liao, Shengjia Zuo, Hong Cheng, Xue-Yan Jiang, Xi-Yong Yu, Jing-Hao Fan, Shi-Ying Li, Lin-Ping Zhao, Rong-Rong Zheng
Publikováno v:
Chemical Communications. 54:7983-7986
An azobenzene-based heteromeric prodrug (hNDP) was prepared for targeted chemotherapy against hypoxic tumor. hNDP could divert the parent drug from nucleus to cytoplasm with lower toxicity, while the azoreduction of hNDP in hypoxia would activate the
Autor:
Gui-Ling Fan, Rong-Rong Zheng, Jing-Hao Fan, Shi-Ying Li, Lin-Ping Zhao, Xi-Yong Yu, Hong Cheng
Publikováno v:
Nanoscale. 11(18)
An abnormal pH microenvironment results from the development of tumors, and also affects the therapeutic efficiency of anti-tumor drugs. In this work, a Forster resonance energy transfer (FRET)-based theranostic fluorescent nanoprobe was constructed
Autor:
Gui-Ling Fan, Xiao-Ya Zhao, Rong-Rong Zheng, Jing-Hao Fan, Shi-Ying Li, Xi-Yong Yu, Hong Cheng, Lin-Ping Zhao, Ping Yuan
Publikováno v:
Macromolecular bioscience. 19(4)
In this paper, a self-delivery chimeric peptide PpIX-PEG8 -KVPRNQDWL is designed for photodynamic therapy (PDT) amplified immunotherapy against malignant melanoma. After self-assembly into nanoparticles (designated as PPMA), this self-delivery system
Autor:
Gui-Ling Fan, Jing-Hao Fan, Hong Cheng, Xi-Yong Yu, Shi-Ying Li, Xiao-Zhong Qiu, Ping Yuan, Fu-An Deng
Publikováno v:
Biomaterials. 224:119497
In recent years, epigenetics has attracted great attentions in the field of biomedicine, which is used to denote the heritable changes in gene expression without any variation in DNA sequence, including DNA methylation, histone modification and so on
Autor:
Gui-Ling Fan, Hong Cheng, Lin-Ping Zhao, Xue-Yan Jiang, Xi-Yong Yu, Rong-Rong Zheng, Jing-Hao Fan, Shi-Ying Li, Xian-Zheng Zhang, Bin Yang
Publikováno v:
Biomaterials. 188
Mitochondria and cell membrane play important roles in maintaining cellular activity and stability. Here, a single-agent self-delivery chimeric peptide based nanoparticle (designated as M-ChiP) was developed for mitochondria and plasma membrane dual-