Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Jing Xian, Teo"'
Autor:
Qiu Xuan Tan, Nicholas B. Shannon, Weng Khong Lim, Jing Xian Teo, Daniel R. Y. Yap, Sze Min Lek, Joey W. S. Tan, Shih Jia J. Tan, Josephine Hendrikson, Ying Liu, Gillian Ng, Clara Y. L. Chong, Wanyu Guo, Kelvin K. N. Koh, Cedric C. Y. Ng, Vikneswari Rajasegaran, Jolene S.M. Wong, Chin Jin Seo, Choon Kiat Ong, Tony K. H. Lim, Bin Tean Teh, Oi Lian Kon, Claramae S. Chia, Khee Chee Soo, N. Gopalakrishna Iyer, Chin-Ann J. Ong
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionField cancerization is suggested to arise from imbalanced differentiation in individual basal progenitor cells leading to clonal expansion of mutant cells that eventually replace the epithelium, although without evidence.MethodsWe perform
Externí odkaz:
https://doaj.org/article/281912497fc44f628bdcedeb2a207a97
Autor:
Qiao Fan, Hengtong Li, Xiaomeng Wang, Yih-Chung Tham, Kelvin Yi Chong Teo, Masayuki Yasuda, Weng Khong Lim, Yuet Ping Kwan, Jing Xian Teo, Ching-Jou Chen, Li Jia Chen, Jeeyun Ahn, Sonia Davila, Masahiro Miyake, Patrick Tan, Kyu Hyung Park, Chi Pui Pang, Chiea Chuan Khor, Tien Yin Wong, Yasuo Yanagi, Chui Ming Gemmy Cheung, Ching-Yu Cheng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Neovascular age-related macular degeneration (nAMD), along with its clinical subtype known as polypoidal choroidal vasculopathy (PCV), are among the leading causes of vision loss in elderly Asians. In a genome-wide association study (GWAS) c
Externí odkaz:
https://doaj.org/article/24537311521441e4bb486f0f1797ecbd
Autor:
Sock Hoai Chan, Yasmin Bylstra, Jing Xian Teo, Jyn Ling Kuan, Nicolas Bertin, Mar Gonzalez-Porta, Maxime Hebrard, Roberto Tirado-Magallanes, Joanna Hui Juan Tan, Justin Jeyakani, Zhihui Li, Jin Fang Chai, Yap Seng Chong, Sonia Davila, Liuh Ling Goh, Eng Sing Lee, Eleanor Wong, Tien Yin Wong, SG10K_Health Consortium, Shyam Prabhakar, Jianjun Liu, Ching-Yu Cheng, Birgit Eisenhaber, Neerja Karnani, Khai Pang Leong, Xueling Sim, Khung Keong Yeo, John C. Chambers, E-Shyong Tai, Patrick Tan, Saumya S. Jamuar, Joanne Ngeow, Weng Khong Lim
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Clinically significant genetic variation in Asian populations is under-characterized. Here, the authors show the diversity in prevalence and spectrum of human disease and pharmacogenetic variants in a multi-ethnic Asian population.
Externí odkaz:
https://doaj.org/article/117b09c793b9435cbcba4527a4883feb
Autor:
Hui Min Lau, Sandra, Lim Jiin Ying, Jasmine Goh, Chew Yin, Choo, Jonathan, Chow, Cristelle, Simon Ling, Yong Hong Ng, Tan Yi Hua, Jing Xian Teo, Khi Pin Chua, Minning Chin, Weng Khong Lim, Jamuar, Saumya Shekhar, Hwei Meeng Lai, Angeline, Kuan Goh, Jeannette Lay
Publikováno v:
Clinical Dysmorphology; Oct2024, Vol. 33 Issue 4, p176-182, 7p
Autor:
Weizhuang Zhou, Yu En Chan, Chuan Sheng Foo, Jingxian Zhang, Jing Xian Teo, Sonia Davila, Weiting Huang, Jonathan Yap, Stuart Cook, Patrick Tan, Calvin Woon-Loong Chin, Khung Keong Yeo, Weng Khong Lim, Pavitra Krishnaswamy
Publikováno v:
Journal of Medical Internet Research, Vol 24, Iss 7, p e34669 (2022)
BackgroundConsumer-grade wearable devices enable detailed recordings of heart rate and step counts in free-living conditions. Recent studies have shown that summary statistics from these wearable recordings have potential uses for longitudinal monito
Externí odkaz:
https://doaj.org/article/53779a435fe84936a61d6c49417d853d
Low frequency variants associated with leukocyte telomere length in the Singapore Chinese population
Autor:
Xuling Chang, Resham L. Gurung, Ling Wang, Aizhen Jin, Zheng Li, Renwei Wang, Kenneth B. Beckman, Jennifer Adams-Haduch, Wee Yang Meah, Kar Seng Sim, Weng Khong Lim, Sonia Davila, Patrick Tan, Jing Xian Teo, Khung Keong Yeo, Yiamunaa M., Sylvia Liu, Su Chi Lim, Jianjun Liu, Rob M. van Dam, Yechiel Friedlander, Woon-Puay Koh, Jian-Min Yuan, Chiea Chuen Khor, Chew-Kiat Heng, Rajkumar Dorajoo
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-9 (2021)
Xuling Chang et al. study whether low frequency variants are associated with leukocyte telomere length and whether these variants predispose to incident cancers and mortalities among East Asians. They find that three East Asian specific variants at P
Externí odkaz:
https://doaj.org/article/d9e076b9b5cf4b79a5a972b56a383c9a
Autor:
Yasmin Bylstra, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R. Ryanne Wu, Jing Xian Teo, Sonia Davila, Jyn Ling Kuan, Sock Hoai Chan, Nicolas Bertin, Cheng Xi Yang, Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Saumya Shekhar Jamuar, Geoffrey S. Ginsburg, Lori A. Orlando, Patrick Tan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-11 (2021)
Abstract Background Family history has traditionally been an essential part of clinical care to assess health risks. However, declining sequencing costs have precipitated a shift towards genomics-first approaches in population screening programs rend
Externí odkaz:
https://doaj.org/article/c63732b2d27a4a86a9c0d7a20529368c
Autor:
Ai Huey Tan, Adeline Su Lyn Ng, Norlisah Mohd Ramli, Weng Khong Lim, Peng Loon Cheah, Jing Xian Teo, Jyn Ling Kuan, Yi Jayne Tan, Jia Lun Lim, Elaine Guo Yan Chew, Jia Nee Foo, Khean Jin Goh, Eng-King Tan, Shen-Yang Lim
Publikováno v:
Neurology Asia. 28:185-189
A significant proportion of adult-onset neurological disorders remain diagnostic odysseys despite extensive evaluation. Hypomyelination with Brainstem and Spinal Cord Involvement and Leg Spasticity (HBSL) is an autosomal recessive disorder caused by
Autor:
Yasmin Bylstra, Weng Khong Lim, Sylvia Kam, Koei Wan Tham, R. Ryanne Wu, Jing Xian Teo, Sonia Davila, Jyn Ling Kuan, Sock Hoai Chan, Nicolas Bertin, Cheng Xi Yang, Steve Rozen, Bin Tean Teh, Khung Keong Yeo, Stuart Alexander Cook, Saumya Shekhar Jamuar, Geoffrey S. Ginsburg, Lori A. Orlando, Patrick Tan
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/b547334243994244971a55f64bd83b9f
Autor:
Melissa Song Ting Wong, Terrence Thomas, Jiin Ying Lim, Sylvia Kam, Jing Xian Teo, Jianhong Ching, Chew Yin Jasmine Goh, Saumya Shekhar Jamuar, Weng Khong Lim, Ai Ling Koh
Publikováno v:
Clinical Dysmorphology.