Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Jing Shan Hu"'
Autor:
Martin Bechem, Volker Laux, Bo Tang, Chunyan Luo, Qiuyun Chen, Kirsten Leineweber, Elisabeth Pook, Qing Kenneth Wang, Shing Hu Cheung, Weiyi Zhang, Jing Shan Hu, Sisi Li
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1863:2319-2332
Low androgen levels are associated with an increased risk of coronary artery disease (CAD), thrombosis and myocardial infarction (MI), suggesting that androgen has a protective role. However, little is known about the underlying molecular mechanism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595c251fa0f4ed00d0526fe3af531246
https://doi.org/10.1016/j.bbadis.2017.06.015
https://doi.org/10.1016/j.bbadis.2017.06.015
Autor:
Fan Wang, Elisabeth Pook, Shing-Hu Cheung, Xiang Ren, Yinhong Song, Chengqi Xu, Bo Tang, Jing-Shan Hu, Stephen Archacki, Xin Tu, Weiyi Zhang, Qiuyun Chen, Weifeng Huang, Qing Kenneth Wang, Tie Ke, Volker Laux, Martin Bechem, Kirsten Leineweber, Chunyan Luo, Jian Yang
Publikováno v:
Gene. 753:144805
Genomic variants in both ADTRP and TFPI genes are associated with risk of coronary artery disease (CAD). ADTRP regulates TFPI expression and endothelial cell functions involved in the initiation of atherosclerotic CAD. ADTRP also specifies primitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07814fd4da75b6aa9c943632b8d48395
https://doi.org/10.1016/j.gene.2020.144805
https://doi.org/10.1016/j.gene.2020.144805
Autor:
T. Kumar, Jennifer A. Wargo, Sangeetha M. Reddy, Jing Shan Hu, Sapna Pradyuman Patel, Adi Diab, Tiziana Cotechini, Miles C. Andrews, Jacob Austin-Breneman, J. M. Gardner, Lauren E. Haydu, Zachary A. Cooper, V. B. Jensen, P. L. Chen, Carrie R. Daniel, Hussein Abdul-Hassan Tawbi, J. E. Lee, Katayoun Rezvani, Spencer C. Wei, Yu Zhang, James P. Allison, Wei Shen Chen, Amin M. Alousi, Patrick Hwu, Isabella C. Glitza, M. Petaccia de Macedo, Nadim J. Ajami, Jianhua Zhang, R. Szczepaniak Sloane, Luigi Nezi, Jessica Galloway-Peña, Roy F. Chemaly, Scott E. Woodman, Courtney W. Hudgens, Nicolas Pons, Elizabeth M. Burton, E. Sirmans, Diane S. Hutchinson, Alexander J. Lazar, Alexandre Reuben, Rodabe N. Amaria, P.A. Futreal, Alexandria P. Cogdill, Wen-Jen Hwu, Laurence Zitvogel, Vancheswaran Gopalakrishnan, Michael T. Tetzlaff, D. Vicente, Alton G. Swennes, Florencia McAllister, Lisa M. Coussens, Christine N. Spencer, Samuel A. Shelburne, Michael A. Davies, Luis M Vence, Elizabeth J. Shpall, Li Zhao, Pablo C. Okhuysen, Takahiro Tsujikawa, Robert R. Jenq, Pradeep Sharma, T. Manzo, Joseph F. Petrosino, Tatiana Karpinets, Hong Jiang, E. Marcelo Riquelme Sanchez, Jeffrey E. Gershenwald, Peter A. Prieto, K. Hoffman
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2018, 359 (6371), pp.97-103. ⟨10.1126/science.aan4236⟩
Science, American Association for the Advancement of Science, 2018, 359 (6371), pp.97-103. ⟨10.1126/science.aan4236⟩
Good bacteria help fight cancer Resident gut bacteria can affect patient responses to cancer immunotherapy (see the Perspective by Jobin). Routy et al. show that antibiotic consumption is associated with poor response to immunotherapeutic PD-1 blocka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d47c6231d710b1caaeb7f814dc34ed7
https://hal.inrae.fr/hal-02629159
https://hal.inrae.fr/hal-02629159
Autor:
Jing-Shan Hu, Sisi Li, Weiyi Zhang, Kirsten Leineweber, Martin Bechem, Chunyan Luo, Elisabeth Pook, Bo Tang, Qiuyun Chen, Volker Laux, Qing Wang, Shing-Hu Cheung
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 37
Low androgen levels are associated with an increased risk of coronary artery disease (CAD), thrombosis and myocardial infarction (MI), suggesting that androgen has a protective role. However, little is known about the underlying molecular mechanism.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::618bb22f69c56d0bf8597fee345ecaaf
https://doi.org/10.1161/atvb.37.suppl_1.409
https://doi.org/10.1161/atvb.37.suppl_1.409
Autor:
Elina Khurgin, Brian B. Hoffman, Mark Durst, Thomas R. Gingeras, Jing-Tyan Ma, David J. Balaban, Jing-Shan Hu, Vivi Truong, Reinhold Kerb
Publikováno v:
Annals of the New York Academy of Sciences. 919:9-15
An important aspect of the drug development process is prediction of efficacious and toxic side effects. Profiling of mRNA expression is a powerful approach to analyze the molecular phenotype of cells under various conditions, for example, in respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7942b679161bf7c19bcd18fa4b560796
https://doi.org/10.1111/j.1749-6632.2000.tb06862.x
https://doi.org/10.1111/j.1749-6632.2000.tb06862.x
Autor:
Hui Wang, Jing-shan Hu, Melissa S. Cline, David Kulp, Manuel Ares, Tyson A. Clark, David Haussler, Gang Lu, Michael A. Siani-Rose, Earl Hubbell, Gangwu Mei
Publikováno v:
ISMB (Supplement of Bioinformatics)
Motivation: Alternative splicing allows a single gene to generate multiple mRNAs, which can be translated into functionally and structurally diverse proteins. One gene can have multiple variants coexisting at different concentrations. Estimating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9630a79344669565033f0816cd34d198
https://doi.org/10.1093/bioinformatics/btg1044
https://doi.org/10.1093/bioinformatics/btg1044
Publikováno v:
Molecular and Cellular Biology. 12:1031-1042
Proteins containing the basic-helix-loop-helix (B-HLH) domain have been shown to be important in regulating cellular differentiation. We have isolated a cDNA for a human B-HLH factor, denoted HEB, that shares nearly complete identity in the B-HLH dom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeaab3c31be19af2f97ac758ec4ab3bd
https://doi.org/10.1128/mcb.12.3.1031
https://doi.org/10.1128/mcb.12.3.1031
Autor:
Gary Peltz, Siyu Fu, Xun Zhang, Jinzhi Chen, Mohammad R. Masjedizadeh, Hong Hsing Liu, Timothy A. Garrow, William Tao, Yanzhou Liu, Kevin D. Welch, Steve A. De Keczer, Kimberly Dolim, Betty Bosano, Jonathan Usuka, Jing Shan Hu, Zhaomei Zhang, Erin Farrell, Janet Cheng, John Allard, Peng Lu, Ayako Kuroda, Paul Weller, Guochun Liao, Joseph Pease, Yingying Guo, Ming Zheng
Publikováno v:
Genome research. 20(1)
Acetaminophen-induced liver toxicity is the most frequent precipitating cause of acute liver failure and liver transplant, but contemporary medical practice has mainly focused on patient management after a liver injury has been induced. An integrativ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541c40fef0c809ebff6bdbde54c6e2b6
https://pubmed.ncbi.nlm.nih.gov/19923254
https://pubmed.ncbi.nlm.nih.gov/19923254
Publikováno v:
Journal of Biological Chemistry. 265:1556-1562
Type beta transforming growth factor (TGF-beta) is a multifunctional regulator of cell growth and differentiation. In the BC3H1 muscle cell line, TGF-beta blocks the onset of differentiation when added to undifferentiated myoblasts and causes dediffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbb5cff18caf57010c5d142e696f112e
https://doi.org/10.1016/s0021-9258(19)40053-7
https://doi.org/10.1016/s0021-9258(19)40053-7
Autor:
John E. Blume, Tyson A. Clark, Simon Cawley, Jing-shan Hu, Gang Lu, Melissa S. Cline, Hui Wang, Alan Williams, Nathan Salomonis
Publikováno v:
ISMB (Supplement of Bioinformatics)
Scopus-Elsevier
Scopus-Elsevier
Motivation: Many or most mammalian genes undergo alternative splicing, generating a variety of transcripts from a single gene. New information on splice variation is becoming available through technology for measuring expression levels of several exo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f16bc6c3c073fd8d4c33adfc7af97618
https://pubmed.ncbi.nlm.nih.gov/15961447
https://pubmed.ncbi.nlm.nih.gov/15961447