Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Jing Nan Shen"'
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-12 (2021)
Abstract Background Osteosarcoma is the most common primary bone tumor in children and adolescents. However, some patients with osteosarcoma develop resistance to chemotherapy, leading to a poor clinical prognosis. Hence, effective therapeutic agents
Externí odkaz:
https://doaj.org/article/366651645fe94488811cbdd0a5128f9e
Autor:
Hong-Bo Li, Gang Huang, Jian Tu, Dong-Ming Lv, Qing-Lin Jin, Jun-Kai Chen, Yu-Tong Zou, Dung-Fang Lee, Jing-Nan Shen, Xian-Biao Xie
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104142- (2022)
Summary: Background: Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents. The molecular mechanism behind OS progression and metastasis remains poorly understood, which limits the effectiveness of current therapies. RNA N6
Externí odkaz:
https://doaj.org/article/ac1260129e30429c85108cf29fe8ec08
Publikováno v:
Operative Neurosurgery. 24:232-241
Autor:
Bi-Cheng Yong, Jin-Chang Lu, Xian-Biao Xie, Qiao Su, Ping-Xian Tan, Qing-Lian Tang, Jing Wang, Gang Huang, Ju Han, Hong-Wen Xu, Jing-Nan Shen
Publikováno v:
Tumor Biology, Vol 39 (2017)
Osteosarcomas are common bone malignancies in children and adolescents. LDOC1 (leucine zipper, down-regulated in cancer 1), a tumor suppressor, is down-regulated in many cancers. In this study, we investigated the role of LDOC1 in tumor metastasis an
Externí odkaz:
https://doaj.org/article/eacfd51f74e649899056d121c1a5c056
Autor:
Hong-Bo Li, Gang Huang, Jian Tu, Dong-Ming Lv, Qing-Lin Jin, Jun-Kai Chen, Yu-Tong Zou, Dung-Fang Lee, Jing-Nan Shen, Xian-Biao Xie
Publikováno v:
EBioMedicine. 82
Osteosarcoma (OS) is the most common primary malignant bone tumor in adolescents. The molecular mechanism behind OS progression and metastasis remains poorly understood, which limits the effectiveness of current therapies. RNA NLiquid chromatography-
Autor:
Xian-biao Xie, Jun-qiang Yin, Li-li Wen, Zhen-hua Gao, Chang-ye Zou, Jin Wang, Gang Huang, Qing-lian Tang, Chiara Colombo, Wei-ling He, Qiang Jia, Jing-nan Shen
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47375 (2012)
Bufalin is the primary component of the traditional Chinese herb "Chan Su". Evidence suggests that this compound possesses potent anti-tumor activities, although the exact molecular mechanism(s) is unknown. Our previous study showed that bufalin inhi
Externí odkaz:
https://doaj.org/article/611b7e9d47614074bd90cfffb3581b9b
Autor:
Ju Han, Ping Xian Tan, Xian Biao Xie, Qing Lian Tang, Jing Wang, Bi Cheng Yong, Gang Huang, Qiao Su, Jing Nan Shen, Jin Chang Lu, Hong Wen Xu
Publikováno v:
Tumor Biology, Vol 39 (2017)
Osteosarcomas are common bone malignancies in children and adolescents. LDOC1 (leucine zipper, down-regulated in cancer 1), a tumor suppressor, is down-regulated in many cancers. In this study, we investigated the role of LDOC1 in tumor metastasis an
Autor:
Qi Sheng Feng, Tiebang Kang, Xiao Feng Zhu, An Jia Han, Binhua P. Zhou, Qing Lian Tang, Yi Liang, Chang Ye Zou, Ru Hua Zhang, Jin Wang, Jun Qiang Yin, Yi Xin Zeng, Dawei Liu, Wu Guo Deng, Bi Cheng Yong, Jing Nan Shen, Zhiqiang Zhao, Qiong Chen, Xian Biao Xie
Publikováno v:
JNCI: Journal of the National Cancer Institute. 104:749-763
Background Glycogen synthase kinase-3b (GSK-3b), a serine/threonine protein kinase, may function as a tumor suppressor or an oncogene, depending on the tumor type. We sought to determine the biological function of GSK-3b in osteosarcoma, a rare pedia
Publikováno v:
Medical Oncology. 28:636-643
Osteosarcoma is a life-threatening malignancy that most often occurs in teenagers. Ezrin is a cytoskeleton linker protein that is actively involved in the metastatic capacity of cancer cells. In this study, we investigated the expression change of ez
Autor:
Qian-Chen, Guo, Jing-Nan, Shen, Song, Jin, Jin, Wang, Gang, Huang, Long-Juan, Zhang, Jun-Qiang, Yin, Chang-Ye, Zou, Ming-Tao, Li
Publikováno v:
Acta Pharmacologica Sinica. 28:850-858
Aim: Comparative proteomics provide a powerful approach in screening for alterations in protein levels and post-translational modifications that are associated with tumors. In the present study, we aimed to identify candidate biomarkers to distinguis