Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Jing Jing Xiao"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102072- (2023)
Paired SpCas9 nickases (SpCas9n) are an effective strategy to reduce off-target effect in genome editing. However, this approach is not efficient with 3′-overhanging ends, limiting its applications. In order to expand the utility of paired SpCas9n
Externí odkaz:
https://doaj.org/article/8c880b1b54f84caeabaf083b01abb9ed
Autor:
Si-Cheng Liu, Yi-Li Feng, Xiu-Na Sun, Ruo-Dan Chen, Qian Liu, Jing-Jing Xiao, Jin-Na Zhang, Zhi-Cheng Huang, Ji-Feng Xiang, Guo-Qiao Chen, Yi Yang, Chao Lou, Hao-Dan Li, Zhen Cai, Shi-Ming Xu, Hui Lin, An-Yong Xie
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-32 (2022)
Abstract Background Due to post-cleavage residence of the Cas9-sgRNA complex at its target, Cas9-induced DNA double-strand breaks (DSBs) have to be exposed to engage DSB repair pathways. Target interaction of Cas9-sgRNA determines its target binding
Externí odkaz:
https://doaj.org/article/3baeafdd016e47d9820a0acff3a8a5a0
Autor:
Xiao-Juan Tan, Zhi-Wei Zhang, Jing-Jing Xiao, Wei Wang, Feng He, Xuan Gao, Bin Jiang, Liang Shen, Xu Wang, Yang Sun, Guo-Ping Zhu
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Soft rot caused by Dickeya zeae is an important bacterial disease affecting rice and other plants worldwide. In this study, Nanopore and Illumina sequencing platforms were used to sequence the high-quality complete genome of a novel D. zeae strain WH
Externí odkaz:
https://doaj.org/article/1edb37c640684f2a9929c09c6acfc417
Autor:
Yu-qing, Yang, Lei, Wang, Mei-ling, Huang, Jing-jing, Xiao, Mei-chen, Wei, Jiang, Wu, Jun-sheng, Hao, Rui, Ling, Nan-lin, Li
Publikováno v:
In Experimental and Molecular Pathology June 2019 108:150-155
Publikováno v:
Archives of Gynecology and Obstetrics. 308:281-290
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a6f8244faa5404a4e3289a545948f9b
https://doi.org/10.1007/s00404-023-06926-9
https://doi.org/10.1007/s00404-023-06926-9
Autor:
Yi-Li Feng, Si-Cheng Liu, Ruo-Dan Chen, Xiu-Na Sun, Jing-Jing Xiao, Ji-Feng Xiang, An-Yong Xie
Publikováno v:
Nucleic Acids Research. 51:2740-2758
In CRISPR/Cas9 genome editing, the tight and persistent target binding of Cas9 provides an opportunity for efficient genetic and epigenetic modification on genome. In particular, technologies based on catalytically dead Cas9 (dCas9) have been develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2f9366261dac71b4c6ff7021e9a1d2c
https://doi.org/10.1093/nar/gkad116
https://doi.org/10.1093/nar/gkad116
Autor:
Tao Guo, Yi-Li Feng, Jing-Jing Xiao, Qian Liu, Xiu-Na Sun, Ji-Feng Xiang, Na Kong, Si-Cheng Liu, Guo-Qiao Chen, Yue Wang, Meng-Meng Dong, Zhen Cai, Hui Lin, Xiu-Jun Cai, An-Yong Xie
Publikováno v:
Genome Biology, Vol 19, Iss 1, Pp 1-20 (2018)
Abstract Background Many applications of CRISPR/Cas9-mediated genome editing require Cas9-induced non-homologous end joining (NHEJ), which was thought to be error prone. However, with directly ligatable ends, Cas9-induced DNA double strand breaks may
Externí odkaz:
https://doaj.org/article/484d2ce754364ad4b477514bdff406f4
Publikováno v:
Journal of Central South University. 29:3847-3857
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::948e29dd01eec767051884595c6b06ff
https://doi.org/10.1007/s11771-022-5217-0
https://doi.org/10.1007/s11771-022-5217-0
Autor:
Chao Lv, Nan He, Jie Jie Yang, Jing Jing Xiao, Yan Zhang, Jun Du, Shi Zuo, Hai Yang Li, Huajian Gu
Publikováno v:
The British Journal of Radiology. 96
Objective: We present a new artificial intelligence-powered method to predict 3-year hepatocellular carcinoma (HCC) recurrence by analysing the radiomic profile of contrast-enhanced CT (CECT) images that was validated in patient cohorts. Methods: Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07d2a55cc4229230a4fa41fcd1c291f5
https://doi.org/10.1259/bjr.20220702
https://doi.org/10.1259/bjr.20220702
Publikováno v:
Horticulturae, Vol 7, Iss 5, p 117 (2021)
Pepper is a thermophilic crop, shallow-rooted plant that is often severely affected by abiotic stresses such as heat, salt, and drought. The growth and development of pepper is seriously affected by adverse stresses, resulting in decreases in the yie
Externí odkaz:
https://doaj.org/article/11f2cfe66b5b419fbae1d2f448eff397