Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jing Chyi Wang"'
Autor:
Weir-Torn Jiaang, Teng-Kuang Yeh, Szu-Yuan Pu, Pei-Shan Wu, Han-Shu Hu, Chung-Pu Wu, Jyh-Haur Chern, Tsu-An Hsu, Jing-Chyi Wang, Andrew Yueh, Yu-Sheng Chao, Hui-Mei Lin, Chi-Cheng Yang
Publikováno v:
Antimicrobial Agents and Chemotherapy. 56:44-53
Hepatitis C virus (HCV) is a global health problem, affecting approximately 3% of the world's population. The standard treatment for HCV infection is often poorly tolerated and ineffective. Therefore, the development of novel or more effective treatm
Autor:
Andrew Yueh, Jing Chyi Wang, Chi Chen Yang, Ming Han Tsai, Yu-Sheng Chao, Ren Huang Wu, Hui Mei Lin, Szu-Yuan Pu, Tzu Ming Jao
Publikováno v:
Journal of Virology
Reverse genetics is a powerful tool to study single-stranded RNA viruses. Despite tremendous efforts having been made to improve the methodology for constructing flavivirus cDNAs, the cause of toxicity of flavivirus cDNAs in bacteria remains unknown.
Autor:
Tsu-An Hsu, Jyh-Haur Chern, Yen-Shian Wu, Andrew Yueh, Li-Wen Wang, Iou-Jiun Kang, Yen-Chun Lee, Jing-Chyi Wang, Sheng-Ju Hsu, Chung-Chi Lee, Yu-Sheng Chao
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6063-6068
A novel class of arylthiourea HCV inhibitors bearing various functionalities, such as cyclic urea, cyclic thiourea, urea, and thiourea, on the alkyl linker were designed and synthesized. Herein we report the synthesis and structure-activity relations
Publikováno v:
Intervirology. 51:253-260
Objective: This study aimed to determine the effects of HBx on the inhibition of tumorigenesis in nude mice injected with CCL13-HBx cells. Therefore, the characteristics of the induced tumors and the phenomenon of apoptosis were assessed. Methods: Th
Publikováno v:
Virus Research. 102:133-139
The hepatitis B virus X gene, which encodes the HBx protein, has multiple functions and is involved in hepatocarcinogenesis. However, the exact role of HBx in hepatocarcinogenesis is still controversial. We have established an inducible (tet-off syst
Publikováno v:
Virus Research. 59:203-210
Plasmids containing PCR-amplified hepatitis B virus e antigen (HBeAg) genes (HBeAg-MV and HBeAg-SV) were constructed and expressed in E. coli strain DH5alpha. The induced intracellular glutathione S-transferase (GST) fusion proteins of HBeAg-MV and H
Autor:
Teng-Kuang Yeh, Weir-Torn Jiaang, Tsu-An Hsu, Pei-Shan Wu, Han-Shu Hu, Jyh-Haur Chern, Andrew Yueh, Jing-Chyi Wang, Chi-Chen Yang, Su-Ying Wu, Wen-Hung Wang, Yu-Sheng Chao, Hui-Mei Lin
Hepatitis C virus (HCV), a member of the Flaviviridae family, affects approximately 3% of the world's population and is becoming the leading cause of liver disease in the world. Therefore, the development of novel or more effective treatment strategi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::950225dda7733ba1f5ed83762af719f7
https://europepmc.org/articles/PMC3553732/
https://europepmc.org/articles/PMC3553732/
Autor:
Jing-Chyi Wang, Yu-Sheng Chao, Teng-Kuang Yeh, Sheng-Ju Hsu, Chung-Chi Lee, Yen-Chun Lee, Jyh-Haur Chern, Yen-Shian Wu, Andrew Yueh, Li-Wen Wang, Iou-Jiun Kang
Publikováno v:
Bioorganicmedicinal chemistry. 18(17)
A series of novel conformationally-restricted thiourea analogs were designed, synthesized, and evaluated for their anti-HCV activity. Herein we report the synthesis, structure–activity relationships (SARs), and pharmacokinetic properties of this ne
Publikováno v:
2007 IEEE International Workshop on Radio-Frequency Integration Technology.
A CMOS down-conversion folded mixer for the radio frequency (RF) applications is presented. The proposed mixer composes of frequency doubling circuits, transconductance stages, and folded switching stages. With input 1.9 GHz RF signals of -40 dBm dri
Publikováno v:
Intervirology. 51(1)
Objective: The known function of hepatitis B virus X protein (HBx) is to determine the fate of cells by modulating various signaling pathways. In our previous study, we demonstrated that HBx inhibits tumor formation in nude mice injected with CCL13-H