Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jing‐Wen Bai"'
Notch3 restricts metastasis of breast cancers through regulation of the JAK/STAT5A signaling pathway
Autor:
Min-Na Chen, Ze-Xuan Fang, Zheng Wu, Jing-Wen Bai, Rong-Hui Li, Xiao-Fen Wen, Guo-Jun Zhang, Jing Liu
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-15 (2023)
Abstract Purpose To explore the potential role of signal transducer and activator of transcription 5A (STAT5A) in the metastasis of breast cancer, and its mechanism of regulation underlying. Methods and results TCGA datasets were used to evaluate the
Externí odkaz:
https://doaj.org/article/d7ca1f7782ac41059430844d2afe8dc9
Autor:
Ji‐Wei Li, Qiu‐Min Deng, Jian‐Ling Zhu, Wei Min, Xiao‐Yi Hu, Hong‐ Yu Chen, Zhong Luo, Lin‐Ling Lin, Xiao‐Long Wei, Yong‐Qu Zhang, Kang‐Liang Lou, Yi‐Yang Gao, Guo‐Jun Zhang, Jing‐Wen Bai
Publikováno v:
MedComm, Vol 4, Iss 6, Pp n/a-n/a (2023)
Abstract Estrogen receptor α (ERα) serves as an essential therapeutic predictor for breast cancer (BC) patients and is regulated by epigenetic modification. Abnormal methylation of cytosine phosphoric acid guanine islands in the estrogen receptor 1
Externí odkaz:
https://doaj.org/article/d782978519d347b0ad247158a9f01a0d
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-32 (2023)
Abstract Targeted anticancer drugs block cancer cell growth by interfering with specific signaling pathways vital to carcinogenesis and tumor growth rather than harming all rapidly dividing cells as in cytotoxic chemotherapy. The Response Evaluation
Externí odkaz:
https://doaj.org/article/18034cb271c74c9da07e07b947dac2e1
Autor:
Yong-Qu Zhang, Yuan-Ke Liang, Yang Wu, Min Chen, Wei-Ling Chen, Rong-Hui Li, Yun-Zhu Zeng, Wen-He Huang, Jun-Dong Wu, De Zeng, Wen-Liang Gao, Chun-Fa Chen, Hao-Yu Lin, Rui-Qin Yang, Jiang-Wen Zhu, Wan-Ling Liu, Jing-Wen Bai, Min Wei, Xiao-Long Wei, Guo-Jun Zhang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 6, Pp 1-16 (2021)
Abstract Notch receptors (Notch1–4) play critical roles in tumorigenesis and metastasis of malignant tumors, including breast cancer. Although abnormal Notch activation is related to various tumors, the importance of single receptors and their mech
Externí odkaz:
https://doaj.org/article/16de3419a8a24638b1ca92d9bab9d292
Autor:
Yong-Qu Zhang, Fan Zhang, Yun-Zhu Zeng, Min Chen, Wen-He Huang, Jun-Dong Wu, Wei-Ling Chen, Wen-Liang Gao, Jing-Wen Bai, Rui-Qin Yang, Huan-Cheng Zeng, Xiao-Long Wei, Guo-Jun Zhang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
PurposeThe basic helix-loop-helix transcription factor (bHLH) transcription factor Twist1 plays a key role in embryonic development and tumorigenesis. p53 is a frequently mutated tumor suppressor in cancer. Both proteins play a key and significant ro
Externí odkaz:
https://doaj.org/article/97a73eaef83a410692141dadcc8b5a22
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Accumulating evidence indicates that N6-methyladenosine (m6A), which directly regulates mRNA, is closely related to multiple biological processes and the progression of different malignancies, including breast cancer (BC). Studies of the aberrant exp
Externí odkaz:
https://doaj.org/article/dfe2c7737d6040bebf0e96a752539907
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Nearly 70% of breast cancers express the estrogen receptor (ER) and are hormone-dependent for cell proliferation and survival. Anti-estrogen therapies with aromatase inhibitors (AIs), selective estrogen receptor modulators (SERMs) or selective estrog
Externí odkaz:
https://doaj.org/article/58b9b7aaaf814e899503dce0a1922f88
Autor:
Wen-Qiang Cui, Qian-Wei Qu, Jin-Peng Wang, Jing-Wen Bai, God'spower Bello-Onaghise, Yu-Ang Li, Yong-Hui Zhou, Xing-Ru Chen, Xin Liu, Si-Di Zheng, Xiao-Xu Xing, Nsabimana Eliphaz, Yan-Hua Li
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Glutamine synthetase (GS), which catalyzes the production of glutamine, plays essential roles in most biological growth and biofilm formation, suggesting that GS may be used as a promising target for antibacterial therapy. We asked whether a GS inhib
Externí odkaz:
https://doaj.org/article/1ccfa3c4c3d542c2a33f2fbeef6eb99f
Autor:
Wen-Ya Ding, Si-Di Zheng, Yue Qin, Fei Yu, Jing-Wen Bai, Wen-Qiang Cui, Tao Yu, Xing-Ru Chen, God'spower Bello-Onaghise, Yan-Hua Li
Publikováno v:
Frontiers in Chemistry, Vol 6 (2019)
We synthesized chitosan grafted with β-cyclodextrin (CD-g-CS) from mono-6-deoxy-6-(p-toluenesulfonyl)-β-cyclodextrin and chitosan. Two different amounts of immobilized β-cyclodextrin (β-CD) on CD-g-CS (QCD: 0.643 × 103 and 0.6 × 102 μmol/g) we
Externí odkaz:
https://doaj.org/article/5f7d024be9db4d558e7408887e3452db
Autor:
Yanbei Yang, Jianqing Chen, Yulin Zhao, Jing-Wen Bai, Wen-Ya Ding, Yonghui Zhou, Xue-Ying Chen, Di Liu, YanHua Li
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
S. suis (Streptococcus suis) caused serious disease symptoms in humans and pigs. S. suis is able to form thick biofilms and this increases the difficulty of treatment. After growth with 1/2 MIC of azithromycin, 1/4 MIC of azithromycin, or 1/8 MIC of
Externí odkaz:
https://doaj.org/article/6d647798a11f44d68ebce75c8cd0c609