Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Jing‐Shan Shi"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundSenescence-accelerated mouse prone 8 (SAMP8) and age-matched SAMR1 mice are used to study the pathogenesis and therapeutics of Alzheimer’s disease (AD); however, the molecular mechanisms are not completely understood.ObjectiveThis study a
Externí odkaz:
https://doaj.org/article/0f28bf38c3e24ef6a9311d06c955bc64
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 8, Iss , Pp 100288- (2023)
Dendrobium nobile is a well-known traditional Chinese herbal medicine, and DNLA (Dendrobium nobile Lindl. alkaloids) is the active ingredient to have anti-brain aging effects in laboratory animals. The aim of the present study is to examine the anti-
Externí odkaz:
https://doaj.org/article/7b4c290cc6d44b549244726babd03d06
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 8, Iss , Pp 100279- (2023)
Introduction: Cinnabar (96% HgS) is included in Chinese medicines, including Hua-Feng-Dan. We have shown the protective effects of Hua-Feng-Dan against LPS plus rotenone-induced neurotoxicity in rats and against LPS plus MPTP-induced neuroinflammatio
Externí odkaz:
https://doaj.org/article/1b0ff71614f3414f874ebe91e86764db
Autor:
Xin-Hao Ji, Ting-Ting Liu, Ai-Hong Wei, Hui-Ping Lei, Yue Chen, Ling-Nan Wu, Ju Liu, Ying Zhang, Fei Yan, Mei-Xiang Chen, Hai Jin, Jing-Shan Shi, Shao-Yu Zhou, Feng Jin
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
ObjectiveTo investigate the mechanism of RNA-binding protein hnRNP A1 in mouse hippocampal neurons (HT22) on glycolysis.MethodsRIP and CLIP-qPCR were performed by HT22 in vitro to observe the mechanism of hnRNP A1 regulating the expression of key pro
Externí odkaz:
https://doaj.org/article/55cdb3bd55b54be9a85888b532a55ada
Publikováno v:
Experimental Gerontology, Vol 177, Iss , Pp 112198- (2023)
Senescence-accelerated mouse prone 8 (SAMP8) mice exhibit cognitive defects and neuron loss with aging, and were used to study anti-aging effects of Dendrobium nobile alkaloids (DNLA). DNLA (20 and 40 mg/kg) were orally administered to SAMP8 mice fro
Externí odkaz:
https://doaj.org/article/74e12fa8301d4a628f7c415e9272709c
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 7, Iss , Pp 100250- (2023)
Introduction: Dendrobium is the famous Chinese medicine. Dendrobium nobile Lindl. alkaloids (DNLA) is the active ingredient and has been shown to have anti-aging, anti-Alzheimer's disease, and neuroprotective properties. This study examined effect of
Externí odkaz:
https://doaj.org/article/8f87629e2d1c4a5184db652828be573f
Autor:
Lin-Zhen Li, Liang Chen, Yang-Li Tu, Xiang-Jie Dai, Sheng-Jia Xiao, Jing-Shan Shi, Yong-Jun Li, Xiao-Sheng Yang
Publikováno v:
Molecules, Vol 28, Iss 17, p 6426 (2023)
Plant-derived phytochemicals have recently drawn interest in the prevention and treatment of diabetes mellitus (DM). The seeds of Moringa oleifera Lam. are widely used in food and herbal medicine for their health-promoting properties against various
Externí odkaz:
https://doaj.org/article/36a2b98c5e9e42a2aad2eca5296c08e6
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 5, Pp 972-977 (2022)
At present, treatments for Alzheimer’s disease can temporarily relieve symptoms but cannot prevent the decline of cognitive ability and other neurodegenerative changes. Dendrobium nobile Lindl alkaloid is the main active component of Dendrobium nob
Externí odkaz:
https://doaj.org/article/1bfde316fce449e096e3d0d291f639c4
Autor:
An-jing Lu, Li-gang Cao, Dao-peng Tan, Lin Qin, Yan-liu Lu, Yong-xia Zhao, Yong Qian, Chao-jun Bai, Ji-yong Yang, Hua Ling, Jing-shan Shi, Zhou Yang, Yu-qi He
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 11, Pp 104208- (2022)
Dendrobium nobile alkaloids (DNLA) and glycosides are the main active components extracted from Dendrobium nobile Lindl. (D. nobile) used for thousands of years in China. The pharmacological effects of the above chemical components are significantly
Externí odkaz:
https://doaj.org/article/d9563febede44e23bc35b143804db106
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Alzheimer’s disease (AD) is a neurodegenerative disorder recognized as a global public health priority. Although available treatments temporarily relieve the symptoms, they could not prevent the progression of cognitive decline. Natural compounds h
Externí odkaz:
https://doaj.org/article/3796ebdbd97941cb82bf6f864d4efe1e