Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Jinfu Peng"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
This study aimed to determine the effect of vitamin D (VD) deficiency on the efficacy and pharmacokinetics of pravastatin and clarify whether the effects are mediated by Organic anion-transporting polypeptides (OATPs). Experiments were conducted in r
Externí odkaz:
https://doaj.org/article/3749415b7fe44fed8cca1f4df7e592e0
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
PM2.5, also known as fine particles, refers to particulate matter with a dynamic diameter of ≦2.5 μm in air pollutants, that carries metals (Zn, Co, Cd) which can pass through the alveolar epithelium and enter the circulatory system and tissues. P
Externí odkaz:
https://doaj.org/article/375bd14dfe6444c0ba04f264d0976ec7
Autor:
Zhijun Huang, Mengyao Wang, Li Liu, Jinfu Peng, Chengxian Guo, Xiaoping Chen, Lu Huang, Jieqiong Tan, Guoping Yang
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
Hepatic cytochrome P450 enzyme activities correlate with non-alcoholic fatty liver disease (NAFLD) and hepatic steatosis. The decreased activity of CYP3A4, an important drug-metabolizing enzyme, is associated with the progression of NAFLD. CYP3A4 is
Externí odkaz:
https://doaj.org/article/8dfeb4ebee6e439a94b81c004deaec29
Publikováno v:
Clinica Chimica Acta. 531:177-182
Double stranded DNA (dsDNA) is known to act as a damage-associated molecular pattern (DAMP) that stimulates the body's innate immune response. In general, cyclicGMP-AMP(cGAMP)synthase(cGAS), a DNA sensor, detects these disease-causing DNA and activat
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 50(5)
Pregnant women are frequently prescribed drugs to treat chronic diseases such as human immunodeficiency virus infection, but little is known about the benefits and risks of these drugs to the fetus that are driven by fetal drug exposure. The latter c
Publikováno v:
Biochemical Pharmacology. 204:115235
Heart failure remains a considerable clinical and public health problem, it is the dominant cause of death from cardiovascular diseases, besides, cardiovascular diseases are one of the leading causes of death worldwide. The survival of patients with
Publikováno v:
Drug Metab Dispos
Pregnancy can significantly change the pharmacokinetics of drugs, including those renally secreted by organic anion transporters (OATs). Quantifying these changes in pregnant women is logistically and ethically challenging. Hence, predicting the in v
Background: PM2.5 , also known as fine particles, refers to particulate matter with a dynamic diameter of ≦ 2.5 µm in air pollutants, carrying toxic substances (e.g. heavy metals or minerals), which can pass through the alveolar epithelium and ent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::593e0e330431bac3e20156831ceb9c4a
https://doi.org/10.21203/rs.3.rs-87265/v1
https://doi.org/10.21203/rs.3.rs-87265/v1
Autor:
Yong Huo, Shanjie Jiang, Honghao Zhou, Gaofeng Zeng, Qiulian Fang, Yuming Zhang, Shan Tu, Jie Huang, Yun Kuang, Hongyi Tan, Yimin Cui, Fanghua Xu, Xiaoliang Chen, Chan Zou, Chee M. Ng, Jingjing Cai, Zhiyuan Yang, Xue Sun, Jianqiang Peng, Jianping Zeng, Wanying Yu, Guozuo Xiong, Weihong Jiang, Jingjing Yu, Haigang Li, Qi Pei, Xiangjiang Shi, Xianming Wu, Zhijun Huang, Guoping Yang, Liying Gong, Zaixin Yu, Yuxia Xiang, Jinfu Peng, Hao Gong, Hong Yuan, Lu Huang, Liu Yang, Xiaoyan Wang, Da Miao, Xiaobin Wang, Chunmei Lv, Xiaoping Chen, Zijing Peng, Qiong Yang, Jie Wu, Xiaomin Wang, Peng Chen, Wenyu Liu, Jingle Li, Xiaohong Tang, Chengxian Guo, Haiying Dai, Zewei Ouyang
Publikováno v:
Circulation: Genomic and Precision Medicine. 13
Background: Warfarin is an effective treatment for thromboembolic disease but has a narrow therapeutic index; optimal anticoagulation dosage can differ tremendously among individuals. We aimed to evaluate whether genotype-guided warfarin dosing is su
Publikováno v:
Nutrition (Burbank, Los Angeles County, Calif.). 74
Vitamin D supplementation and vitamin D deficiency are common in clinical experience and in daily life. Vitamin D not only promotes calcium absorption and immune regulation, but also changes drug effects (pharmacodynamics and adverse reactions) and d