Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Jinfu Nie"'
CT radiomics-based model for predicting TMB and immunotherapy response in non-small cell lung cancer
Autor:
Jiexiao Wang, Jialiang Wang, Xiang Huang, Yanfei Zhou, Jian Qi, Xiaojun Sun, Jinfu Nie, Zongtao Hu, Shujie Wang, Bo Hong, Hongzhi Wang
Publikováno v:
BMC Medical Imaging, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Tumor mutational burden (TMB) is one of the most significant predictive biomarkers of immunotherapy efficacy in non-small cell lung cancer (NSCLC). Radiomics allows high-throughput extraction and analysis of advanced and quantitat
Externí odkaz:
https://doaj.org/article/cee62da4007a454498d9530134c46c73
Autor:
Qizhi Zhu, Meng Fu, Jian Qi, Ziming Xu, Yongguang Wang, Zhipeng Wang, Dan Wang, Jiajia Liu, Ruiping Du, Xin Wei, Hongzhi Wang, Jinfu Nie, Bo Hong, Weiping Xu
Publikováno v:
iScience, Vol 27, Iss 8, Pp 110413- (2024)
Summary: Platinum-based chemo-resistance is the major issue for the treatment of small cell lung cancer (SCLC). The integrative analysis of multi-omics data is a reliable approach for discovering novel biomarkers associated with chemo-resistance. Her
Externí odkaz:
https://doaj.org/article/10ad811d4e8f4936b675944207aaabfb
Autor:
Yunsheng Cheng, Yanyan Xu, Xiaopeng Zhang, Jian Qi, Jialiang Wang, Yanzhe Liu, Kun Wan, YanWei Liu, Liang Yu, Hongzhi Wang, Jinfu Nie, Bo Hong, Yong Wang
Publikováno v:
Genes and Diseases, Vol 10, Iss 6, Pp 2245-2247 (2023)
Externí odkaz:
https://doaj.org/article/94e37b8c6b954bf78e73abba92fe3818
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Background Small cell lung cancer (SCLC) is a very malignant tumor with rapid growth and early metastasis. Platinum-based chemo-resistance is the major issue for SCLC treatment failure. Identifying a new prognostic model will help to make an
Externí odkaz:
https://doaj.org/article/43548ea10c004809ac57856fdbbb6ac6
Autor:
Min Zhu, Xingjie Li, Xu Cheng, Xingxu Yi, Fang Ye, Xiaolai Li, Zongtao Hu, Liwei Zhang, Jinfu Nie, Xueling Li
Publikováno v:
BMC Medical Genomics, Vol 15, Iss S2, Pp 1-15 (2022)
Abstract Background Tumor microenvironment plays pivotal roles in carcinogenesis, cancer development and metastasis. Composition of cancer immune cell subsets can be inferred by deconvolution of gene expression profile accurately. Compositions of the
Externí odkaz:
https://doaj.org/article/039c74925f334f59923492b1f9fe19f4
Autor:
Rui Tao, Wei Cao, Feng Zhu, Jinfu Nie, Hongzhi Wang, Lixiang Wang, Pengcheng Liu, Hailong Chen, Bo Hong, Dahai Zhao
Publikováno v:
Thoracic Cancer, Vol 12, Iss 11, Pp 1647-1655 (2021)
Abstract Over the past decades, low‐dose computed tomography (LD‐CT) screening has been widely used for the early detection of lung cancer. Increasing numbers of indeterminate pulmonary nodules are now being discovered. However, it remains challe
Externí odkaz:
https://doaj.org/article/c5c96f48da274bb68bf301ff222d18dc
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 306 (2023)
(1) Background: Ovarian cancer (OV) has the high mortality rate among gynecological cancers worldwide. Inefficient early diagnosis and prognostic prediction of OV leads to poor survival in most patients. OV is associated with ferroptosis, an iron-dep
Externí odkaz:
https://doaj.org/article/860b5aa39d694c5789d3dd9816567efe
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Autophagy is a programmed cell degradation mechanism that has been associated with several physiological and pathophysiological processes, including malignancy. Improper induction of autophagy has been proposed to play a pivotal r
Externí odkaz:
https://doaj.org/article/443371a0b61c42f69be408b629e8b436
Autor:
Yongli Shan, Yanqi Zhang, Yuan Zhao, Tianyu Wang, Jingyuan Zhang, Jiao Yao, Ning Ma, Zechuan Liang, Wenhao Huang, Ke Huang, Tian Zhang, Zhenghui Su, Qianyu Chen, Yanling Zhu, Chuman Wu, Tiancheng Zhou, Wei Sun, Yanxing Wei, Cong Zhang, Chenxu Li, Shuquan Su, Baojian Liao, Mei Zhong, Xiaofen Zhong, Jinfu Nie, Duanqing Pei, Guangjin Pan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Neurogenesis is an ordered transition from pluriptotent cells to neural precursor cells (NPCs) to neurons. Here the authors show that loss of the lysine demethylases JMJD3 and UTX leads reduced DNA accessibility at neurogenesis loci in human NPCs, an
Externí odkaz:
https://doaj.org/article/80505987d5cf4b679818c2110e0c8333
AURKA rs2273535 T>A Polymorphism Associated With Cancer Risk: A Systematic Review With Meta-Analysis
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Aurora kinase A (AURKA) is a cell cycle regulatory serine/threonine kinase that promotes cell cycle progression. It plays an important role in regulating the transition from G2 to M phase during mitosis. The association between the AURKA rs2273535 T>
Externí odkaz:
https://doaj.org/article/b0d739c3d049457c9103374799954ae6