Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Jinfei Mei"'
Publikováno v:
ChemPhysMater, Vol 3, Iss 3, Pp 303-313 (2024)
Gamma secretase (GS) is an intramembranous enzyme that acts on the amyloid precursor protein and Notch inside lipid membranes. The enzyme is responsible for amyloid-β propagation, one of the well-known causes of Alzheimer's disease. However, the eff
Externí odkaz:
https://doaj.org/article/9c05b2fe324843b680203a1073144bcc
Publikováno v:
ChemPhysMater, Vol 1, Iss 4, Pp 310-320 (2022)
Accumulating evidence suggests that toxicity in patients with Alzheimer's disease originates from the deposition of Aβ42 aggregates on the neuronal cell membrane. However, the molecular mechanism underlying Aβ42 aggregation on the surface of differ
Externí odkaz:
https://doaj.org/article/f1bae502364c4d6d8d9df15bba71ca51
Publikováno v:
ChemPhysMater; Jul2024, Vol. 3 Issue 3, p303-313, 11p
Autor:
Jinfei Mei, Huijuan Yang, Sajjad Ahmad, Xiaohong Ma, Wen Xu, Wenqi Gao, Ye Li, Chuanbo Wang, Hongqi Ai
Publikováno v:
ACS Chemical Neuroscience. 13:2048-2059
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2a57b952301e483ddf7fe45b5fc1205
https://doi.org/10.1021/acschemneuro.2c00311
https://doi.org/10.1021/acschemneuro.2c00311
Publikováno v:
Physical Chemistry Chemical Physics. 24:12267-12280
APP9mer prefers to embed in the pocket of SD1 in a parallel orientation and generate the most probable APPmer-SD1 stable complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a456d9fb9921bfe359080d2b788e948a
https://doi.org/10.1039/d2cp00569g
https://doi.org/10.1039/d2cp00569g
Publikováno v:
ChemistrySelect. 7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32efda65de390b293550c15ce7af9086
https://doi.org/10.1002/slct.202202217
https://doi.org/10.1002/slct.202202217
Publikováno v:
ACS Chemical Neuroscience. 12:1197-1209
Heavy evidence has confirmed that Aβ42 oligomers are the most neurotoxic aggregates and play a critical role in the occurrence and development of Alzheimer's disease by causing functional neuron death, cognitive damage, and dementia. Disordered Aβ4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b3af604278ae0bd3af2cb120321ba72
https://doi.org/10.1021/acschemneuro.1c00047
https://doi.org/10.1021/acschemneuro.1c00047
Publikováno v:
Journal of molecular modeling. 28(10)
Leukocyte immunoglobulin-like receptor B2 (LilrB2) is one of discovered cell surface β-amyloid (Aβ) receptors and taken as a promising therapeutic target for the treatment of Alzheimer's disease (AD). Aβ42 oligomer rather than monomer is toxic to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685febb7afe5262ea9ec69c215df372f
https://pubmed.ncbi.nlm.nih.gov/36125588
https://pubmed.ncbi.nlm.nih.gov/36125588
Autor:
Yujie Cao, Tianran Sheng, Jinfei Mei, Peng Qian, Deqian Huang, Liangquan Sheng, Guoping Sheng
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67aa069f0dc9141fde54527777cb0f8a
https://doi.org/10.2139/ssrn.4156082
https://doi.org/10.2139/ssrn.4156082
Autor:
Yujie Cao, Tianran Sheng, Jinfei Mei, Peng Qian, Deqian Huang, Liangquan Sheng, Guoping Sheng
Publikováno v:
Applied Catalysis B: Environmental. 319:121892
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14f9de8cea5b6e75aa7786d62a62f3eb
https://doi.org/10.1016/j.apcatb.2022.121892
https://doi.org/10.1016/j.apcatb.2022.121892